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Recent years have brought major shifts in the way endoscopic retrograde cholangiopancreatography is used in everyday practice, including the incorporation of endoscopic ultrasound (EUS) techniques with ERCP. The 4th Edition of this practical reference helps you make the most of today's ERCP in your practice, with authoritative, highly illustrated guidance on every aspect of this complex tool, including coverage of the latest techniques both in print and on video. - Provides detailed, full-color illustrations and in-depth instructions for performing all procedures. - Depicts each procedure in dozens of step-by-step videos that clearly show ERCP techniques and imaging interpretation, including many new or recently improved procedures. - Covers recent advancements in balloon assisted endoscopy, and provides guidance on performing ERCP on patients with surgically altered anatomy. - Includes new chapters on endoscopic disinfection to address antibiotic resistant bacterial infections traced back to duodenoscopes; the environmental implications of ERCP; and magnetic biliary anastomosis. - Contains clear therapeutic guidelines that help you determine when and when not to perform ERCP. - Any additional digital ancillary content may publish up to 6 weeks following the publication date.

Highly practical and user-friendly, ExpertDDx: Abdomen and Pelvis, third edition, helps you reach accurate, clinically useful differential diagnoses in your everyday practice. It presents the most useful differential diagnoses for each region of the abdomen and pelvis, grouped according to anatomic location, generic imaging findings, modality-specific findings, or clinical-based indications. Each differential diagnosis includes several high-quality, succinctly annotated images; a list of diagnostic possibilities sorted as common, less common, and rare but important; and brief, bulleted text offering helpful diagnostic clues. It's an excellent resource for subspecialty abdominal imagers as well as general radiologists and trainees, providing invaluable assistance in reaching logical, on-target differential diagnoses based on key imaging findings and clinical details. Covers 175 of the most common diagnostic challenges in abdominal and pelvic imaging, enhanced by more than 2,100 radiologic images, full-color illustrations, clinical and histologic photographs, and gross pathology images Provides a quick review of the salient features of each entity, differentiating features from other similar-appearing abnormalities Includes new chapters on hematuria, flank pain, acute scrotal pain, and seminal vesicle Adds greater focus to advancing prostate imaging methods with expanded content on lesions in the peripheral zone and lesions in the transition zone, as well as new coverage of transplant imaging Contains updates to numerous classifications, including LI-RADS for liver, O-RADS for ovarian masses, and the Tanaka classification for pancreatic cysts Features new MR examples and MR-specific diagnoses throughout, plus new differentials for contrast-enhanced ultrasound findings related to liver and kidney lesions

A must-have reference for both beginning and experienced endosonographers, Endosonography, 5th Edition, coves the full spectrum of endoscopic ultrasound (EUS) in a single, convenient resource. Concise, easy-to-navigate chapters keep you abreast of changes in this dynamic field, and nearly 150 procedural videos reinforce techniques of common, clinically relevant procedures. Covering both standard and newer techniques, this authoritative reference covers everything you need to know—from basic applications to advanced interventions. - Guides you step by step through both introductory and advanced techniques, covering everything from interpretation and accurate diagnosis to treatment recommendations. - Employs a user-friendly, templated format to cover all topics from basic applications to advanced interventions, with procedures organized by body system. - Includes a new chapter on Endo-Hepatology, and an increased focus on using EUS for interventions. - Features 20 new procedural videos covering topics such as esophageal and gastric cancer; mediastinal lesions and lung cancer; pancreatic tumors; and bile duct, gallbladder, and ampullary lesions. - Covers recent improvements and new applications in guided fine-needle EUS for diagnosis and cancer staging. - Features high-quality images with correlative illustrations, diagnostic algorithms, examination checklists, and key points boxes throughout. - Provides nearly 150 how-to-videos of both diagnostic and therapeutic procedures performed by expert endosonographers that demonstrate effective techniques and the proper use of equipment. - Provides practical information on establishing an endoscopic practice, from what equipment to buy to effective cytopathology services.

Now fully revised to include recent advances in the field, the third edition of Gastrointestinal and Liver Pathology Pathology, a volume in the Foundations in Diagnostic Pathology series, is an essential foundation text for residents and pathologists. The popular template format makes it easy to use, and new information throughout brings you up to date with what's new in the field, including advances in molecular diagnostic testing and new diagnostic biomarkers. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice.Key features of this practical text include: - A consistent, user-friendly format that explores each entity's clinical features, gross and microscopic findings, ancillary studies, differential diagnoses, and prognostic and therapeutic considerations. - A focus on specific features of selected neoplastic and non-neoplastic entities, including broad and in-depth differential diagnoses. - Clinical information on treatment and prognosis, enabling you to better understand the clinical implications of the diagnosis. - Nearly 1,000 full-color, high-quality illustrations with extensive figure legends, as well as abundant boxes and tables throughout. What's NEW in this edition: - Advances in molecular diagnostic testing and its capabilities and limitations, including targeted/personalized medicine. - New diagnostic biomarkers and their utility in differential diagnosis, newly described variants, and new histologic entities. - The latest TNM staging and WHO classification systems. - New co-editors Drs. Amitabh Srivastava and Daniela S. Allende lead a team of expert, internationally recognized pathologists who keep you up to date with the latest information in the field.

For nearly 50 years, Sleisenger & Fordtran's Gastrointestinal and Liver Disease has been the go-to reference for gastroenterology and hepatology residents, fellows, physicians, and the entire GI caregiving team. Now in a fully revised 11th Edition, this two-volume masterwork brings together the knowledge and expertise of hundreds of global experts who keep you up to date with the newest techniques, technologies, and treatments for every clinical challenge you face in gastroenterology and hepatology. A logical organization, more than 1,100 full-color illustrations, and easy-to-use algorithms ensure that you'll quickly and easily find the information you need. - Features new and expanded discussions of chronic hepatitis B and C, Helicobacter pylori infection, colorectal cancer prevention through screening and surveillance, biologic agents and novel small molecules to treat and prevent recurrences of inflammatory bowel disease (IBD), gastrointestinal immune and autoimmune diseases, and more. - Offers reliable coverage of key topics such as Barrett's esophagus, gut microbiome, enteric microbiota and probiotics, fecal microbiota transplantation, and hepatic, pancreatic, and small bowel transplantation. - Provides more quick-reference algorithms that summarize clinical decision making and practical approaches to patient management. - Employs a consistent, templated, format throughout for quick retrieval of information. - Includes monthly updates online, as well as more than 20 procedural videos. - Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Covering the full spectrum of endoscopic ultrasound, Endosonography, 4th Edition, by Drs. Robert Hawes, Paul Fockens, and Shyam Varadarajulu, is a comprehensive, one-stop resource for mastering both diagnostic and therapeutic EUS procedures. Leading global authorities guide you step by step through both introductory and advanced techniques, covering everything from interpretation and accurate diagnosis to treatment recommendations. High-quality images and an easy-to-navigate format make this updated reference a must-have for both beginning and experienced endosonographers. Provides practical information on establishing an endoscopic practice, from what equipment to buy to providing effective cytopathology services. Employs a user-friendly templated format to cover all topics from basic applications to advanced interventions, with procedures organized by body system. Features completed updated content throughout, including new sections on high-intensity focused ultrasound, through-the-needle biopsy, benign pancreatic masses, and gastro-jejunostomy. Includes perspectives from new contributors who provide global experience and knowledge. Contains new and enhanced illustrations that correlate with high-quality endoscopic images. Teaches clinically relevant techniques through dozens of new how-to videos. Covers cutting-edge techniques for performing therapeutic interventions, such as drainage of pancreatic pseudocysts and EUS-guided anti-tumor therapy, as well as fine needle aspiration (FNA) procedures. Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Now thoroughly up-to-date, Clinical Gastrointestinal Endoscopy, 3rd Edition, by Drs. Vinay Chandrasekhara, Mouen Khashab, B. Joseph Elmunzer, and V. Raman Muthusamy, ensures that you stay current with the latest technology and techniques in GI endoscopy. An all-new editorial team, newly updated images, and a reorganized format make this reference an easy-to-use source of reliable information on a full range of topics, including anatomy, pathophysiology, and therapeutic management options, in addition to the latest GI procedures and technologies. - Offers state-of-the-art coverage of bariatric surgery, therapeutic EUS, device-assisted enteroscopy, image-guided therapy, intramural endotherapy, and much more. - Features 100 updated videos with author voiceovers, as well as 1,000 revised photographs, endoscopic images, and anatomical drawings. - Provides a fresh perspective and expert guidance from an entirely new editorial team. - Includes many more references per chapter, as well as further references online. - Presents material in a newly restructured, organ-based format for quick reference. - Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Over the past 40 years, ERCP has become an effective therapeutic modality with diagnostic purposes that are continually improved.. The 3rd Edition of this practical reference helps you make the most of today's endoscopic retrograde cholangiopancreatography in your practice. You'll find authoritative, highly illustrated guidance on every aspect of ERCP, including coverage of the latest techniques. - Clearly depicts each step of ERCP procedures in dozens of step-by-step videos, including Needle Knife Sphincterotomy, Biliary Sphincterotomy, Cannulation, and Fistulotomy. - Provides clear guidelines on when and when not to perform ERCP. - Features superb, full-color images, and a wealth of illustrative diagrams. - Includes new chapters that cover duodenoscope reprocessing; endomicrocopy; EUS-guided endotherapy related to pancreatobiliary disorders; and CT and MRCP related to pancreatobiliary disorders. - Contains updated information on radiofrequency ablation for cancer, percutaneous vs. endoscopic drainage, scope cleaning practices, and pancreatic necrosis. - Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Many bacteria, viruses, protozoa, and fungi play key roles in the development of gastrointestinal diseases, and this practical reference brings you up to speed with this increasingly important area. Covering a broad range of GI diseases and cancers, this resource provides an expert overview of the field, ideal for all gastroenterologists and infectious disease physicians. - Covers infections associated with gastroesophageal reflux disease and Barrett's esophagus, gallbladder disease, acute pancreatitis, small intestinal bacterial overgrowth, irritable bowel syndrome, inflammatory bowel disease, appendicitis, Whipple Disease, Crohn's Disease, and more. - Discusses esophageal cancer, gastric cancer, cholangiocarcinoma, hepatocellular carcinoma, and colorectal cancer. - Includes chapters on gut microbiome, fecal transplants, and the molecular pathgenesis of gastrointestinal infections. - Consolidates today's available information on this timely topic into a single convenient resource.

A highly clinical focus and clear, vibrant illustrations make Textbook of Clinical Hemodynamics, 2nd Edition, by Dr. Michael Ragosta, the resource of choice for accurately analyzing hemodynamic waveforms generated in cardiac catheterization labs. This easy-to-use, disease-oriented reference—ideal for physicians, nurses, and technicians—offers the unparalleled detail and visual support you need for interpreting the findings you encounter in practice. New coverage throughout keeps everyone on the cardiac team up to date with the latest concepts and skills, ensuring more effective monitoring and treatment of patients with cardiac disease. - Provides a disease-oriented assessment of waveform data that demonstrates how both qualitative and quantitative interpretation can affect clinical decision making. - Features extensive updates throughout, with expanded coverage of aortic valve and mitral valve disorders, including new percutaneous valve treatments (TAVR, mitral clip); comparison of hemodynamic support devices; a new chapter on pulmonary hypertension; and expanded coverage of coronary hemodynamics. - More than 100 brand-new, full-color images provide clear visuals for a more complete understanding of complex concepts. - Includes a new Easy Reference Appendix with clinically useful formulas and data.

Dr. Pyrsopoulos has assembled the top authors in the field to provide current reviews on acute liver failure, to be the first time this topic is addressed in one volume. Topics are devoted to Classification and Epidemiologic Aspects of Acute Liver Failure; Acute Liver Failure: Mechanisms of disease and multi-systemic involvement; The Pathology of Acute Liver Failure; Liver Regeneration in the Acute Liver Failure Patient; Viral Hepatitis and Acute Liver Failure: Still a Problem; Drug- induced Liver Injury and Acute Liver Failure; Acetaminophen and Acute Liver Failure; Non-Viral Or Drug-Induced Etiologies of Acute Liver Failure; The Clinical Spectrum and Manifestations of Acute Liver Failure; Non ICU Management of Acute Liver Failure; Management of Acute Liver Failure in the ICU Setting; Prognostic Models of Acute Liver Failure; The Role of Liver Transplantation in Acute Liver Failure; and Future Approaches and Therapeutic Modalities for Acute Liver Failure. Readers will come away with a current point of view about how to approach and manage the patient with acute liver failure.

Well-organized and vibrantly illustrated throughout, Handbook of Liver Disease is a comprehensive yet concise handbook providing authoritative guidance on key clinical issues in liver disease. The quick-reference outline format ensures that you'll find answers when you need them, and cover-to-cover updates keep you abreast of the recent rapid changes in the field. Written by leading international experts in hepatology, this reference is ideal for hepatologists, gastroenterologists, internists, family practitioners, trainees, and others who diagnose and manage patients with liver disorders. - Uses a highly templated outline format, key points in each chapter, alert symbols, and highlighted review points to provide a'just the facts'approach to daily clinical questions on liver disease. - Features expanded hepatitis chapters, including completely updated coverage of new, safe, and effective oral regimens for the treatment of hepatitis C. - Provides completely updated coverage of: alcoholic liver disease • autoimmune hepatitis • portal hypertension • primary biliary cholangitis • hepatic tumors • cirrhosis • nonalcoholic liver disease • liver transplantation • and more. - Includes the latest information on adolescents with liver disease moving into adult care. - Covers the revised criteria for prioritizing liver transplantation using the MELDNa score, new options for the treatment of hepatocellular carcinoma, and improved management of hepatorenal syndrome.

Get the authoritative, up-to-date information you need on liver disease from the 7th Edition of the most trusted reference worldwide. Covering both basic science and recent clinical developments, this revised edition by Drs. Arun J. Sanyal, Thomas D. Boyer, Norah A. Terrault, and Keith D. Lindor, provides an in-depth, comprehensive look at the pathophysiology, diagnostic, and treatment information related to the liver. More than 1,100 figures and tables, many new and in full color, highlight completely updated content throughout. - Expert, international authorship and comprehensive, easy-to-access information makes this edition the gold standard in the field of hepatology. - Includes new information on the rapid changes in treatment paradigms for acute liver failure, the latest treatments for primary biliary cholangitis, full coverage of the gut microbiome and its role in liver disease, the newest developments in drug-induced liver injury, and changes in hepatitis C virus treatment and hot-button concerns about access to care. - New summary boxes at the end of each chapter and a newly streamlined table of contents make it easier to find and understand the information you're looking for. - Hundreds of brand-new illustrations clearly present key aspects of liver disease.

Dr. Quigley has created a must-have reference on the gut microbiome for the practicing gastroenterologist. A leader in the field of human physiology and digestive disorders, he has laid out the basics on this increasingly important topic, devoting articles to the organization and biology of the human gut microbiome as well as its diagnostic potential. Top international authors have presented articles that discuss the intersection of the gut microbiome and diet and the gut-brain axis. Clinical implications of the gut microbiome are discussed with disease states like IBD, GI cancer, and liver diseases. Finally, the issue ends with the cutting-edge clinical innovation of fecal microbial transplantation. This issue bridges the gap between science and clinical practice and should be an important reference to practicing gastroenterologists.

Dr. Rustgi has assembled the leading experts in the management of Heptatitis B to present the current treatment and clinical course for diagnosis and management of the disease. Articles are devoted to: Drug metabolism in the liver; Mechanism of Liver Damage including the RUCAM scale; Drug-induced acute liver failure; Epidemiology and genetic risk factors; Adverse drug reactions: type A (intrinsic or pharmacological) or type B (idiosyncratic); Pathology of injury including phenotypes; The clinical course of drug-induced liver disease; Environmental factors of drug hepatotoxicity; Newer agents in drug hepatotoxicity; Drug hepatotoxicity: herbal products; Drug hepatotoxicity: models including “human on a chip” and zebrafish; Acute and chronic liver failure from drugs: impact on the kidney; and Management of acute hepatotoxicity including medical agents and liver support systems. Readers will come away with the cutting edge science behind the latest innovations in the treatment of Hepatitis B.

For more than 25 years, Current Therapy in Colon and Rectal Surgery has been the go-to resource for preparing for the American Board of Surgery certification exam. Following in this tradition, the 3rd Edition offers a comprehensive, contemporary summary of treatment options for colorectal diseases, with a focus on practical clinical science and applications. In a single, portable volume, you'll find complete coverage of new diagnostic modalities, medical therapeutics, and surgical treatment options, including minimally invasive surgery. Easy to read and digest, it provides a quick consultation with experts on the essentials of colon and rectal surgery. - Consult this title for a quick overview before you enter the OR, and use it as a review tool for board certification and recertification. - Nearly 100 succinct chapters, just 3 or 4 pages each, written by leading experts in colorectal surgery. - Five chapters devoted exclusively to different aspects of rectal cancer. - Other key topics include minimally invasive surgery, reparative surgery, maturing outcomes, and managing surgical risk. - New chapters focus on hot topics such as intestinal transplants, enhanced recovery programs, and the management of peristomal hernias. - Updated information on the molecular biology of colorectal cancer and its implications for therapy.

Endoscopic access to the small bowel has advanced significantly since the introduction of video capsule endoscopy and deep enteroscopy in early 2000. Other major advances have occurred in imaging modalities involving computed tomography and magnetic resonance studies. Due to these advances, the recent 2015 ACG guideline changed the terminology from “obscure” to “small bowel” bleeding because the majority of cases now can be found to have a small bowel source. The improvements in technology have advanced our ability to visualized vascular findings, inflammatory lesions, and small bowel neoplasms. Articles in this issue are devoted to these improvements in technology.

Due to the current obesity epidemic, non-alcoholic fatty liver disease (NAFLD) is prevalent in a significant portion of the United States patient population. It is being increasingly recognized that NAFLD affects both adults and children and can progress to end stage liver disease with resultant cirrhosis, portal hypertension, and hepatocellular carcinoma. In addition, several extrahepatic conditions may be linked to NAFLD including cardiovascular disease, insulin requiring and type 2 diabetes mellitus, obstructive sleep apnea, colonic adenomas, hyperuricemia, vitamin D deficiency, hyperferritinemia, pancreatic steatosis, hypothyroidism, and polycystic ovarian syndrome. Therapies for NAFLD are evolving rapidly. This issue will analyze patient demographics, risk factors, pathophysiology, patient presentation, and treatments for NAFLD.

The field of inflammatory bowel disease has evolved in many ways. The first has been the revolution in medical therapy for the disease. With the advent of biologic therapy, the aspirational goal of therapy has become mucosal healing. These medications have also made it possible to avoid or delay surgery for ulcerative colitis and Crohn's disease. Although non-invasive strategies such as MR or CT enterography or stool-based assays are helpful, they have not been able to replace the prognostic information provided by endoscopy. Simultaneously, the quality and spectrum of tools available to perform endoscopy has widened. High resolution endoscopes are now the norm and are nearly as good as chromoendoscopy for identifying dysplasia in ulcerative colitis patients. Most gastroenterologists also perform dilations but do not generally do this for patients with IBD. Finally, newer devices such as enteroscopes, endoscopic ultrasound, and endomicroscopes are being incorporated into the algorithms to diagnose and treat complications of IBD. This issue highlights all of these advances by the experts in their fields.

This issue of Surgical Clinics of North America, guest edited by Dr. Adrian Dan, is devoted to Metabolic and Bariatric Surgery. He has assembled expert authors to review the following topics: A Historical Perspective of Metabolic and Bariatric Surgery; The Socio-economic Impact of Morbid Obesity and Factors Affecting Access to Obesity Surgery; Laparoscopic Roux-en-Y Gastric Bypass–Surgical Technique and Peri-operative Care; Revisional Metabolic and Bariatric Surgery; Novel Endoscopic and Surgical Techniques for treatment of Morbid Obesity –A Glimpse into the Future; Management and Prevention of Surgical and Nutritional Complications After Bariatric Surgery; Resolution of Comorbitidies and Impact on Longevity Following Bariatric and Metabolic Surgery; The Effects of Metabolic Surgery upon Fatty Liver Disease and Non-Alcoholic Steatohepatitis; Patient Selection and Surgical Management of High Risk Patients with Morbid Obesity; Laparoscopic Sleeve Gastrectomy–Surgical Technique and Peri-operative Care; Rise and Fall of the LAGB as a Bariatric Procedure; Plastic Surgery and Body Contouring Following Weight Loss Surgery; Biliopancreatic Diversion with Duodenal Switch–Surgical Technique and Periopertive Care; Morbid Obesity, Type 2 Diabetes and the Metabolic Syndrome–Pathophysiologic Relationships and Guidelines for Surgical Intervention; Patient Safety and Quality Improvement Initiatives in Contemporary Metabolic and Bariatric Surgical Practice; Type II Diabetes Mellitus – A Surgical Disease, and more!

This issue details the latest knowledge of early diagnosis, risk factors, limited surgical treatments, and novel therapies for pancreatic diseases. Clinicians will learn the most prognostic scoring systems for acute pancreatitis, review the basics for early management of the disease, and see how current practice guidelines have evolved. Advances in radiological imaging when applied to the pancreas have resulted in enhanced staging and improved selection for surgical intervention. Endoscopy of the pancreas via both ERCP and endoscopic ultrasound has led to unprecedented access and potential for non-operative intervention. Pancreatic surgery now takes advantage of both minimally invasive approaches and techniques learned from organ transplantation. These latest advances are addressed in this issue by key opinion leaders.

Consult the leading text in the field that delivers the information you need to diagnose and treat pediatric gastrointestinal and liver diseases effectively. In one convenient and comprehensive volume, Drs. Robert Wyllie, Jeffrey S. Hyams, and Marsha Kay provide all the latest details on the most effective new therapies, new drugs, and new techniques in the specialty. In addition, the new two-color design throughout helps you find what you need quickly and easily. Full-color endoscopy images to help improve your visual recognition Definitive guidance from renowned international contributors who share their knowledge and expertise in this complex field Detailed diagrams that accurately illustrate complex concepts and provide at-a-glance recognition of disease processes More than 400 board review-style questions, answers, and rationales New therapies for hepatitis B and C, new drugs for the treatment of inflammatory bowel disease, and an expanded discussion of the newest endoscopic and motility techniques available for pediatric patients The most current information on diagnosing and treating abnormalities of protein, fat, and carbohydrate metabolism New chapters on pancreatic transplantation and liver pathology The latest surgical techniques for children with gastrointestinal conditions

HBV is most prevalent viral infection worldwide. Recent advances in HBV virology epidemiology and management are of utmost importance particularly during this time when HCV is taking the front row in discussion and research. However, there's an increased interest in management of HBV in special populations, which is covered in this issue. The authors also explore drugs in the pipeline as well as new approaches for achieving long-term viral suppression and possibly cure.

The topics covered in this issue, an update from what was first published in the Gastrointestinal Endoscopy Clinics in 2008, reflect the fact that NOTES is seeing a resurgence in popularity. Now, eight years later, there is more data to confirm safety, to look at the best options for using natural orifices, and to talk about optimal training scenarios. The Guest Editor has enlisted some of the top experts on NOTES to contribute articles devoted to Seminal Developments: SM Tunnel Technique; Peroral Endoscopic Myotomoy (POEM); Submucosal Tumor Endoscopic Resection; Endoscopic Full Thickness Resection; Submucosal Tunneling for NOTES Procedures Beyond Resection; Pyloromyotomy; New NOTES: Western Perspective; and Why Did the Old NOTES Fail: Lessons Learned that can Guide New NOTES Development.

Dr. Levy has secured the field's top experts to offer the latest clinical reviews on cholestatic liver disease. The issue will include articles devoted to The Gut-Liver Axis; Update on Genetics in Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis; New thoughts on IgG4 Associated Cholangitis; Cancer Risk and Surveillance in PSC; Novel Therapies for PBC; and Liver transplantation for Cholestatic Liver Diseases, to name a few. Dr. Levy's issue will be the most current authority on cholestatic liver disease.

Over a short few decades, the field of pediatric endoscopy has matured from the exploratory to the routine. Performance of endoscopic procedures in children is now a fundamental aspect of the practice of more than 2000 pediatric gastroenterologists in North America, and endoscopic instruments are increasingly being developed with an eye to their pediatric applications. Ensuring safe and effective endoscopy in children requires specific medical knowledge and technical competency, in addition to appropriately designed equipment and settings. Obtaining consent from parents, as well as assent from patients, for the purposes of performing diagnostic and therapeutic gastrointestinal procedures begins with a deep understanding of risks and benefits that endoscopy affords and is typically gained through formal training in the field. Diagnostic endoscopy may help to confirm common pediatric conditions including eosinophilic esophagitis and inflammatory bowel disease, while therapeutic procedures to treat strictures in the GI tract may help children avoid more invasive surgeries. Using endoscopy in children to achieve hemostasis or to remove commonly swallowed foreign bodies, such as lithium batteries or high-powered magnets, can be lifesaving, and the insertion of feeding tubes can help medically complex patients to thrive. In short, pediatric endoscopy is an integral component of healthcare for children, and gaining and understanding of its best practices may help all clinicians to better recognize its role in pediatric disease outcomes.

This issue of Emergency Medicine Clinics, edited by Drs. Joseph Martinez and Autumn Graham, focuses on Abdominal and Gastrointestinal Emergencies. Articles include: Gastrointestinal Bleed ; Abdominal pain in the Immuncompromised Patient Lower Abdominal Pain: Diverticulitis, Colitis, Inflammatory Bowel Disease and Appendicitis;Acute Abdominal Pain in the Bariatric Surgery Patient;The Vomiting Patient: Bowel Obstruction, Cyclic Vomiting and Gastroparesis; Diarrhea; Non-abdominal Abdominal Pain; Evidence Based Approach to Abdominal Pain;Abdominal Pain in the Geriatric Patient; Abdominal Pain in Children; Evaluating the patient with Right upper quadrant abdominal pain, and more!

The goal of this issue of Gastroenterology Clinics is to present GI diseases which affect women uniquely, such as pelvic floor problems and pregnancy related disorders, or which require a more considered approach such as functional bowel disease or autoimmune processes. It will also address the position of women and female gastroenterologists in the health system as a whole. This issue is published at an exciting, transitional time in the future of gastroenterology, as we adjust approaches for the assessment of disease in a large portion of our patient population, and as we address the challenges in practicing medicine based on the uniqueness of specific populations.

In this issue an impressive group of contributors at the forefront of sedation research has been assembled to provide endoscopists and dedicated nursing personnel alike a comprehensive review of important topics in the field sedation and analgesia. A discussion on the pharmacology and agents used to provide moderate and deep sedation provides the basic framework that is a crucial element in determining the driving force behind the developments in sedation and analgesia. An evidence-based approach on the use of unsedated endoscopy is also provided. Other topics included the use of propofol, patient-controlled sedation and analgesia, extended physiologic monitoring, risk management, and quality assurance as they apply to the spectrum of sedation in the endoscopy suite. Sedation and analgesia in the pediatric patient is also addressed.

Richly illustrated and comprehensive in scope, Abdominal Imaging, 2nd Edition, by Drs. Dushyant V. Sahani and Anthony E. Samir, is your up-to-date, one-volume source for evaluating the full range of diagnostic, therapeutic, and interventional challenges in this fast-changing field. Part of the Expert Radiology series, this highly regarded reference covers all modalities and organ systems in a concise, newly streamlined format for quicker access to common and uncommon findings. Detailed, expert guidance, accompanied by thousands of high-quality digital images, helps you make the most of new technologies and advances in abdominal imaging. - Offers thorough coverage of all diagnostic modalities for abdominal imaging: radiographs, fluoroscopy, ultrasound, CT, MRI, PET and PET/CT. - Helps you select the best imaging approaches and effectively interpret your findings with a highly templated, well-organized, at-a-glance organization. - Covers multi-modality imaging of the esophagus, stomach, small bowel, colon, liver, pancreas, gall bladder, bile ducts, spleen, pelvic lymph nodes, kidneys, urinary tract, prostate, and peritoneum. - Includes new chapters on esophageal imaging; 5RECIST, WHO, and other response criteria; and a new section on oncologic imaging. - Keeps you up to date with the latest developments in image-guided therapies, dual-energy CT, elastography, and much more. - Features more than 2,400 high-quality images, including 240 images new to this edition.

In the last three decades, the prevalence of obesity has doubled with over 600 million obese adults worldwide. The gastrointestinal complications of obesity are well publicized; however, the role of the gastrointestinal tract in the development and treatment of obesity is often understated. From the pathophysiologic role of gut hormones and the microbiota, to the purposeful, anatomic derangement of the gastrointestinal tract that is utilized as a treatment for obesity, it is imperative that gastroenterologists understand the full scope of obesity in relation to the gastrointestinal system. Studies suggest that in the U.S. obesity is underrecognized and undertreated by health care providers. Given its complex sociology, pathophysiology, and treatment, obesity, like many other diseases, requires a multidisciplinary approach. Therefore, gastroenterologists must be equipped with the relevant knowledge of obesity that will empower them to properly manage their patients.

This issue of Critical Care Clinics focuses on Gastrointestinal Critical Care. Articles include: Non variceal Upper Gastrointestinal bleeds; Lower Gastrointestinal bleeds; Mesenteric Ischemia; Peritonitis; The open abdomen and intra abdominal infections; Gut motility issues in critical illness; Gut as the motor of multiple organ dysfunction; Intra abdominal hypertension and abdominal compartment syndrome; Abdominal circulatory interactions in critical illness; Severe acute pancreatitis and necrotizing pancreatitis; and Nutrition in the critically ill.

The Guest Editors have assembled key opinion leaders to provide state of the art articles on this important update on ERCP. A chapter on cannulation techniques and sphincterotomy will highlight recent literature on wire-guided cannulation, use of papillotomes, when and if to precut for entry and the use of smart circuitry for papillotomy. A chapter on surgically altered anatomy will highlight the increasing occurrence of biliary tract disease in patient's s/p gastric bypass for obesity along with other surgery and the use of balloon enteroscopes, overtubes and intraoperative procedures A chapter on EUS assisted biliary and pancreatic access will highlight the growing experience with these combine techniques. There is growing literature on preventing post-ercp pancreatitis which is changing the standard of care and Joe Elmunzer is the best person to highlight this. Stu Sherman will review advances in the management of bile duct stones and when to intervene in gallstone pancreatitis. Peter Cotton just published a landmark study on SOD that will change the standard of care and will review the state of the science on this disease as it relates to both biliary tract and pancreatic disease. The management of benign biliary strictures and leaks is evolving with the introduction of covered metal stents and Jacques Deviere is at the forefront. Amrita Sethi will discuss diagnosis of biliary malignancy highlighting the use of FISH, molecular markers and enhanced imaging such as pCLE. Michele Kahaleh will review recent experience with biliary tumor ablation using RFA probes and PDT. Alan Barkun helps endoscopists determine when to use plastic stents, metal stents, and covered stents and when to drain one, two or three segments of liver in patients with malignant biliary obstruction. George Papachristo and Dhiraj Yadav will review most recent data on endoscopic therapy for acute recurrent and smoldering acute pancreatitis. Nagy Reddy will provide on update on endotherapy for painful chronic pancreatitis. Finally, Raj Shah will update on advances in pancreatoscopy and cholangioscopy including the use of ultra slim per-oral scopes and new digital mother/baby scopes.

Helicobacter pylori (H. pylori) infection is a worldwide disease with a significant morbidity and mortality; it is the leading cause of non-ulcer dyspepsia, peptic ulcers and gastric tumors, including low-grade mucosa-associated lymphoid tissue-lymphoma and adenocarcinoma. In addition, it has also been recognized that the interaction between H. pylori and non-steroidal, anti-inflammatory drugs is damaging to the gastroduodenal mucosa. H. pylori treatment still remains a challenge for physicians, since no current first-line therapy is able to cure the infection in all treated patients. This issue will serve to update gastroenterologists on current therapies, evaluation and management of disease progression, and the future of management of H. pylori infection.

This issue of Cardiology Clinics devoted to syncope, a disorder that is associated with increased mortality. Internationally recognized experts discuss the many causes of syncope, helping the clinician to distinguish life-threatening etiologies from benign ones.

Dr. Brown provides a timely upate on the clinical diagnosis and management of Hepatic Encephalopathy. His issue addresses current hot topics including Role of NH4 in Pathogenesis of Hepatic Encephalopathy; How to diagnose and manage HE in fulminant hepatic failure; New methods of Brain Imaging and testing (eg PET) and Hepatic Encephalopathy; Management New agents for HE (focus on NH4 lowering drugs used in UCD); Legal responsibility of MD when he diagnoses HE; Diets in Encephalopathy; and Neurological manifestations of HE.

This issue will be an informative treatise on gastroparesis, a symptomatic chronic disorder of the stomach characterized by delayed gastric emptying in the absence of mechanical obstruction. Gastroparesis is an increasingly recognized and diagnosed disorder. Treatment can be challenging due to several mechanisms which play a role in causing the symptoms. Symptoms of gastroparesis are variable and include early satiety, nausea, vomiting, bloating, and upper abdominal discomfort. These symptoms can range from mild to severe leading to such complications as malnutrition, functional disability, and multiple hospitalizations. The three most common etiologies are diabetes, post-surgical, and idiopathic (unknown). Treatment consists of dietary manipulation, medical, and surgical therapy. The articles will provide a comprehensive review and in-depth information on gastroparesis. Each chapter will be written by an expert in the area. This issue will give the reader a better appreciation for the breadth of gastroparesis.

A thorough update is presented by the Guest Editors on the diagnosis, treatment, and management of Barrett's Esophagus. Not only do they address the most pertinent clinical issues like screening, biomarkers, surveillance, therapeutics, and predictors of disease progression but they present state of the art material on therapeutic/treatment modalities like EMR, ESD, and ablative therapy. Further, articles are presented on epidemiology, molecular pathogensis, and cost-analysis studies so that the reader will come away with a comprehensive update on Barrett's Esophagus.

Clinics Collections: Gastrointestinal Diseases draws from Elsevier's robust Clinics Review Articles database to provide multidisciplinary teams, including general practitioners, gastroenterologists, otolaryngologists, oncologists, pathologists, and surgeons, with practical clinical advice and insights on this highly prevalent condition and its comorbidities. Clinics Collections: Gastrointestinal Diseases guides readers on how to apply current primary research findings on gastrointestinal diseases to everyday practice to help overcome challenges and complications, keep up with new and improved treatment methods, and improve patient outcomes. • Areas of focus include gastroesophageal reflux disease, Barrett's esophagus, upper gastrointestinal bleeding, dyspepsia, eosinophilic esophagitis, gastroparesis, dysphagia, esophageal tumor, colon polyps/cancer, constipation, inflammatory bowel disease, gastroenteritis, lower gastrointestinal bleeding, and hemorrhoids. • Each article begins with keywords and key points for immediate access to the most critical information. • Articles are presented in an easy-to-digest and concisely worded format. Elsevier's Clinics Collections provide concise reviews of today's most prevalent conditions and significant medical developments. Other Clinics Collections titles available include Type II Diabetes Mellitus, Asthma, Obesity, Pain Management, Lipid Disorders, and Chronic Obstructive Pulmonary Disease.

Dr. Flamm has invited a group of distinguished hepatologists to provide insight into the assessment of a variety of scenarios where clinical judgment based on experience and published literature is an invaluable addition to the care of individual patients. Articles included in the issue address the following topics: Evaluation and Management of Portal Vein Thrombosis, Liver Disease in the HIV patient, Hepatocellular Carcinoma, Evaluation of Renal Insufficiency in the Cirrhotic Patient, Contemporary Management of Autoimmune Hepatitis, Diagnosis and Treatment of Overlap Syndromes, Ins and Outs of Liver Imaging for the Gastroenterologist, Contemporary Assessment of Hepatic Fibrosis, A Primer on Liver Transplantation Immunosuppressive Agents for the Gastroenterologist, Evaluation of Jaundice in the Hospitalized Patient, Liver Disease in the Adolescent, Evaluation and Management of Hemochromatosis and How and When to Administer Hepatitis A and B Virus Vaccinations. These are all common contemporary reasons for consultations for Gastroenterologists and Hepatologists and this issue will address the issues in a pragmatic way.

- La AEG (Asociación Española de Gastroenterología), a través de su departamento de docencia, coordina una serie de monografías que recogen la información clínica más novedososa que se está generando en esta especialidad. - El proyecto comienza con una serie de monografías de un elevado nivel ciéntífico y en las que participarán expertos nacionales e internacionales con una acreditada trayectoria tanto clínica como investigadora. - Clínicas Iberoamericanas de Gastroenterología y Hepatología nace con el objetivo de convertirse en un proyecto a largo plazo que recoja publicaciones periódicas que permitan mantener al día al lector en aquellos temas más complejos y a la vez actuales de la especialidad. - Cada una de las monografías estaría integrada por un total de 10 manuscritos orientados para que el lector pueda disfrutar de una visión global de la condición tratada. - En este título se hace una revisión epidemiológica de la enfermedad inflamatoria intestinal, así como una sencilla explicación de los avances genéticos que se han producido y su relación con la clínica. Esta monografía dedica también un capítulo a las técnicas de imagen empleadas en el diagnótico de esta patología, sin olvidar el abordaje de temas tales como la relación de la enfermedad inflamatoria intestinal y el embarazo o la importancia de la participación del paciente en el control de la enfermedad. - El proyecto global de AEG Clinics contará además con dos Directores de renombre que serán los doctores Antoni Castells, del, Servicio de Gastroenterología del Hospital Clinico de Barcelon y Henry Cohen, Ex-Presidente de la World Gastroenterology Organization. Clínicas Iberoamericanas de Gastroenterología y Hepatología nace con el objetivo de recoger la información clínica más novedosa y transmitir el estado actual del conocimiento en las diferentes disciplinas que componen la especialidad. El proyecto global de AEG Clinics contará además con dos Directores de renombre que serán los doctores Antoni Castells, del Servicio de Gastroenterología del Hospital Clínic de Barcelona y Henry Cohen, Ex-Presidnete de la World Gastroenterology Organization. Cada una de las monografías estaría integrada por un total de 10 manuscritos orientados para que el lector pueda disfrutar de una visión global de la condición tratada y que le permitan mantenerse al día en aquellos temas más complejos y a la vez actuales de la especialidad. En este título se hace una revisión epidemiológica de la enfermedad inflamatoria, así como una sencilla explicación de los avances genéticos que se ha producido y su relación con la clínica.

This issue would review a broad range of endoscopic complications throughout the entire GI tract and include complications related to almost all types of endoscopic procedures. Typically, articles and endoscopy courses only briefly mention specific types of complications related to one or two endoscopic procedures. To date, this would be the only issue whose sole focus is on endoscopic complications and their management and will prove a useful resource for the gastroenterologist. The authors will be expert endoscopists from around the country whose knowledge of this topic should be far ranging and include use of new devices.

Colonoscopy is the bread and butter for endoscopists and advances in the procedure to reduce time, improve efficiency, and prevent errors are very important for this group. The newest advances look at colonoscopy efficiency and a better way to target tissue sampling, which avoids random biopsies and instead looks at ways to predict areas for sampling. The Guest Editors have selected top experts to provide these important updates and they also address current thinking that questions the continued value of colonoscopies as predictors of colon cancer. The issue will be a very popular one, and it needs to be heavily promoted.

Dr. Robert Gore (co-editor of Textbook of Gastrointestinal Radiology) has assembled an expert panel of authors on the topic of The Acute Abdomen. Articles will include: Evaluating the patient with right upper quadrant pain; Evaluating the patient with left upper quadrant pain; Evaluating the patient with right lower quadrant pain; Evaluating the patient with left lower quadrant pain; Acute pancreatitis; Acute disorders of the abdominal aorta; Bowel obstruction; Bowel ischemia; Acute infectious and inflammatory enterocolitides; Acute urinary tract disorders; Acute gynecologic disorders; Evaluating the acute abdomen in the pregnant patient; MR evaluation of the acute, non-traumatic abdomen in adolescents and adults; and more!