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•Written by practicing key opinion leaders in neurology. •Covers basic aspects of Parkinsonism with description of various symptoms, pathophysiology, and management approach. •Describes in detail the role of amantadine in the management of parkinsonism highlighting its clinical and safety parameters. •Illustrated and summarized with tables and figures to enhance reading experience. •One-stop information for practising neurologists and clinical practitioners on parkinsonism and role of amantadine.