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Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. With an estimated 80% of people with diabetes living in disadvantaged regions, and the key roles of lipoproteins in the pathogenesis of the chronic complications of diabetes, this volume will be relevant to many readers globally. It is our intention that the contents will advance knowledge of the readers who will use it to contribute to the reduction of the burden associated with altered lipoproteins in people with diabetes. The second edition of this book provides an updated and comprehensive review of the field. The book, which includes many tables and figures, is presented in three main sections: (i) Lipoprotein metabolism, qualitative changes and measurements; (ii) Lipoproteins and the complications of diabetes; and (iii) the treatment of lipoproteins in diabetes. Each chapter from the first edition has been updated, and new topics added. New topicsinclude the links between glycemia and lipoproteins, the role of lipoproteins in ischemic stroke, the diagnosis and management of statin intolerance (which is thought to be more common in people with diabetes) and the use of PCSK9 inhibitors and fish oils in the management of lipoproteins in people with diabetes. This book is written by an international group of experts in the clinical, laboratory and research aspects of lipoproteins in diabetes. Lipoproteins in Diabetes Mellitus, 2nd Edition is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It is a must-have resource for primary care and specialist clinicians, clinical and basic science researchers and to trainees and students.

This book is the first comprehensive approach on COVID-19 cardiac complications, both during the acute phase as well as in the long-COVID period. It provides an up-to-date and highly illustrated summary of the biology of SARS-CoV-2, the course of COVID-19, risk factors that worsen the disease in COVID-19 patients, clinical features of COVID-19 patients, COVID-19 cardiological complications, treatment, and prevention methods, and long-term cardiological aspects of COVID-19.Chapters provide the reader with a contemporary perspective on the emerging links between COVID-19 and cardiovascular disease. In addition, this volume discusses the clinical implications and therapeutic goals in patients with COVID-19 and cardiac complications, as well as possible therapeutic options. It also offers clear recommendations on how to manage (both non- and pharmacologically) to avoid the increased number of COVID-19 related deaths due to CVD and its risk factors.Cardiovascular Complications of COVID-19 will be the primary resource for physicians, residents, fellows, and nursed and medical students in the fields of cardiology and COVID-19/infectious diseases as well as healthcare providers that initiate preventive activities and dedicated programs.

Despite decades of aggressive pharmaceutical and surgical interventions, coronary artery disease (CAD) remains the number one killer of both men and women in the Western world. The most important aspect in the treatment of CAD is to focus on prevention. Indeed, prevention is easier than cure and when CAD does present itself, a combination of conventional and alternative methodologies can truly make a difference in people's lives. Building upon its predecessor, Nutritional and Integrative Strategies in Cardiovascular Medicine, Second Edition, provides scientific and clinical insight from leaders in the field of cardiovascular medicine who explore an integrative approach to treating and curing cardiovascular diseases through conventional and non-allopathic methodologies. Nutritional interventions with both appropriate non-inflammatory diets and targeted nutraceutical supports are simple and basic strategies to prevent as well as help manage CAD and congestive heart failure (CHF). In fact, nutritional strategies in the treatment of CHF have not only afforded patients a better quality of life but increased survival as well. This evidence-based book describes how to integrate nutrition, supplements, lifestyle changes, and medications for improved outcomes in hypertension, dyslipidemia, diabetes, coronary heart disease, congestive heart failure, infectious myocarditis and much more. Topics include: Covid-19: An evidence-based integrative approach to supporting the myocardium Metabolic cardiology: An exciting new way to manage heart failure Contains information on hypertension and dyslipidemia Naturopathic approaches Mediterranean diet as the longevity diet of the world Value of omega-3s and other fats Role of botanicals in the treatment of cardiovascular disease Integrative care of the patient in extending quality of life Gender-specific medicine – Perhaps a new evolving cardiovascular sub-specialty Role of dental disease inflammation and cardiovascular disease Environmental toxins and the heart Earthing and grounding as an energetic nutrition in healing the heart Autophagy and mTOR – the'new medicine'of the future Nutritional medicine is vitally important in the integrative care of the patient. This book will assist established health professionals as well as students preparing for advanced degrees in healthcare and offer cutting-edge and new information in cardiovascular medicine. It offers simple nutritional supports that can make the difference between not only easing human suffering, but also life and death.

This book is a comprehensive review of pulmonary embolism (PE) which, with deep vein thrombosis, is assigned to the term venous thromboembolism (VTE) and currently the third most frequent acute cardiovascular syndrome globally. In the past decade we have seen a remarkable improvement in new diagnostic tools as well as novel therapeutic options to manage patients with VTE and this book provides a thorough clinical discussion of the diagnosis and management of these patients.Pulmonary Embolism presents a comprehensive review of all aspects of the epidemiology, pathophysiology, diagnosis, risk assessment and therapeutic options to manage the patient with PE. To aid healthcare providers caring for patients with acute PE, it encapsulates a novel, comprehensive, yet simple, pathway for the management of patients with PE, which can be used in many health care systems around the globe. This pathway is at the core of the book and all chapters are related to this unique algorithm.

This book provides an evidence-based approach for the clinical use of nutraceuticals in the prevention and management of cardiovascular disease. It examines cardiovascular disease epidemiology, risk factors, and the role of dietary patterns. Clinical chapters discuss the use of nutraceuticals in the management of medical conditions such as dyslipidemia, hypertension, insulin resistance, and heart failure. Each chapter contains a short epidemiological background; a list of relevant active compounds and their efficacy, tolerability, and safety; and suggestions for prescribers. This book is a practical guide with the best clinical evidence supporting the use of nutraceuticals in cardiology. Nutraceuticals and Cardiovascular Disease: An Evidence-based Approach for Clinical Practice is an essential resource for physicians, residents, fellows, and medical students in cardiology, clinical nutrition, dietetics, and internal medicine.

This second edition provides an updated review on the current guidelines and practice standards for the clinical management of cardiovascular risk factors and prevention of cardiovascular diseases. Endorsed by the American Society for Preventive Cardiology, this practical textbook includes concise descriptions of major and newer risk factors, biomarkers, and best practices in the management and prevention of cardiovascular disease. The manual contains chapters on the epidemiology and risk factors for a variety of cardiovascular diseases including dyslipidemia, hypertension, diabetes, inflammation, and ischemic stroke. It examines behavioral factors, psychosocial stress, family history, nutrition, physical activity, smoking, alcohol use, and other sociocultural factors. In addition, the book discusses new imaging strategies in detection of cardiovascular disease, prevention of heart failure, atrial fibrillation, and peripheral arterial disease, and prevention for special populations. Throughout the manual, recommendations are based on guidelines endorsed by the American College of Cardiology, American Heart Association, and other major societies. The second edition of the ASPC Manual of Preventive Cardiology is an essential resource for physicians, medical students, residents, fellows, nurses, and other healthcare professionals and researchers in cardiology, primary care, health promotion and disease prevention, exercise physiology, and pharmacotherapy.

This thoroughly revised third edition provides a comprehensive grounding on hereditary heart diseases with special emphasis on the genetic aspects of these conditions. It continues to provide the expertise that all cardiologists, clinical and molecular geneticists, and related medical professionals require to provide optimal care for patients with cardiac disease of genetic origin and for their relatives. Topics covered include the different cardiomyopathies, the primary arrhythmia syndromes and the hereditary thoracic aortic disorders. In addition other topics such as cardiac involvement in hereditary neuromuscular diseases, the clinical policy for sudden cardiac death and the possibilities of pre-implantation genetic diagnosis are included to extend the discussion. Clinical Cardiogenetics compiles current knowledge on the topic in an easy to understand reference. It provides a practical clinical primer for cardiologists, clinical geneticists, trainees and other physicians involved in the management of these patients.

This book provides an overview of statin-associated muscle symptoms (SAMS) from clinical presentation to treatment and possible metabolic causes. It examines the risk factors, presentations, diagnosis and differential diagnosis, clinical management, and financial costs of SAMS. The book also highlights patients'perspectives on SAMS such as the psychosocial, emotional, and societal factors influencing their perceptions and experiences. Finally, the book presents the results of observational and clinical trials on the prevalence of SAMS, clinical trials for treatments, and potential future research approaches for improving the understanding and treatment of SAMS. A key addition to the Contemporary Cardiology series, Statin-Associated Muscle Symptoms is an essential resource for physicians, medical students, residents, fellows, and allied health professionals in cardiology, endocrinology, pharmacotherapy, primary care, and health promotion and disease prevention.

This book focuses on CSI cardiology update 2018. Cardiology is a medical specialty and a branch of internal medicine concerned with diseases of the heart. It deals with the diagnosis and treatment of such conditions as congenital heart defects, coronary artery disease, heart failure, and valvular heart disease. This book consists of 24 sections that include coronary artery disease risk factors, lipids and diet, diabetes and heart, hypertension, chronic coronary artery disease, acute coronary syndromes, ST-segment elevation myocardial infarction, dual antiplatelet therapy, coronary intervention, intervention in structural heart disease, cardiac imaging, cardiovascular pharmacology, heart failure, syncope, atrial fibrillation, ventricular arrhythmias, cardiac implantable electronic devices, cardiac surgery, stroke, peripheral vascular disease, women and heart disease, systemic diseases and heart, emerging issues in cardiology, and miscellaneous, which are further divided into 154 chapters. This edition of Cardiology Update – 2018 attempts to bring into sharp focus these very controversial yet relevant topics, with views from Indian experts that define approaches and color practices in our sphere of life. This book is useful not only for residents in training, but also for general physicians and general cardiologists as well as for interventional cardiologists and electrophysiologists.

Arterial stiffness is an emerging risk factor with important implications for cardiovascular disease risk. Herein, we concisely summarize the physiological and pathophysiological aspects of arterial stiffening, and highlight the importance of increased arterial stiffness for future cardiovascular events. Factors contributing to increased arterial stiffness such as advancing age, obesity, race, sex differences and cardiorespiratory fitness are examined while elucidating the potential underlying mechanisms for each scenario. To conclude, we discuss novel interventions to prevent and/or reverse the arterial stiffening process in order to reduce cardiovascular risk.This book also:Overviews the cellular and molecular mechanisms of arterial stiffnessDiscusses the implications of arterial stiffness in target organ damage

“Frontiers in Cardiovascular Drug Discovery” is an Ebook series devoted to publishing the latest and the most important advances in Cardiovascular drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The Ebook series should prove to be of interest to all pharmaceutical scientists involved in research in cardiovascular drug design and discovery. Each volume is devoted to the major advances in cardiovascular drug design and discovery. The Ebook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

Cardiovascular mortality in women is more frequent than breast cancer mortality, a fact which is often overlooked. Women's Heart and Estrogens explores this important women's health issue with respect to estrogen levels (before and after menopause) as the hormone has been known to mediate cardiovascular effects in women. The handbook includes a description of the structure and biological activity of estrogen and follows up with a detailed reference on the genetics behind estrogen and its effect on the cardiovascular system. Subsequent chapters cover the effects of estrogens on the stages of atherogenesis, actions of estrogens on the vascular wall and on cardiovascular metabolic pathways, causes leading to the development of early onset of coronary heart disease in young women (such as vasculitis and autoimmune diseases)[Obaid ur Rahman1], hypercoagulable states, myocardial infarction in hallucinogenic drug abusers, non-atherosclerotic and atherosclerotic coronary heart disease, hormone replacement therapy and postmenopausal risk factors. Medical professionals will also find handy guidelines for cardiovascular disease prevention in women. Women's Heart and Estrogens offers knowledge to readers in a clear and simple manner with detailed images and summaries in each chapter. Guidelines are also presented in a chronological context which demonstrates the development of cardiovascular disease prevention and risk management strategies for women over the years.

Rapid advances in molecular medicine have led to pronounced new developments in experimental and clinical cardiology. In the embrace of modern molecular biology and bridging the gap between the clinical and the genomic, cardiovascular medicine has seen major strides in the understanding of the molecular mechanisms that drive disease progression. The ability to rapidly identify candidate human genes for cardiovascular diseases lends itself to the development of diverse strategies for disease treatment and management. The wide variety of gene expressions proffers excellent targets for novel therapeutics. Gene therapy is steadily increasing in viability and represents a fascinating arena of research and clinical focus. This book is based on two international Mendel symposia on “Genes and the Heart,” joint meetings of the Japanese and European sections of the International Academy of Cardiovascular Sciences. Highlighting selected symposia contributions, this book explores the role of molecular biology and genetics in the basic knowledge, genesis, and clinical interventions of cardiovascular diseases.

This innovative book focuses on HDL and its relationships to triglyceride-rich particles. As new therapies for HDL raising become available, a comprehensive understanding the role of HDL in Coronary Heart Disease is of great importance. This book is an excellent resource for educating physicians and scientists about dyslipidemia and HDL metabolism, including many exogenous substances which interact with and influence HDL. Readers will benefit from the unique visual exposition and the insights of international experts.