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This 2nd edition has been extensively updated and provides comprehensive and current insight into congenital heart diseases, from embryonic development through to clinical features, including human genetics and our current knowledge of the underlying molecular pathways.The book is divided into three parts: an introduction to the development of the heart and its vessels, an overview of the molecular pathways affecting the development of various cardiovascular structures, and a main section focusing on the different types of structural and nonstructural congenital heart diseases, including their clinical features, underlying genetic alterations and insights from animal models and pathways. All chapters have been updated and new chapters added on state-of-the-art approaches including stem cells and organoids, cardiac metabolism, single cell transcriptomics and 3D reconstruction of human heart development. The clinical chapters have been extended and include new sections on diagnostic imaging techniques. Taken together, the book, written by and for clinicians and researchers, provides an integrated and up-to-date resource for all those who want to learn more about both the clinical aspects and the genetic and molecular basis of congenital heart disease.

The second edition of this well-received book will offer both new insights into the intimate mechanisms of transition from hypertension to heart failure and clinical practice advice on the prevention and treatment of heart failure in hypertensive population. Heart failure is the result of the hypertension's effects on the heart and it is a growing public health problem, as it affects 20-50% of the adult population in developed countries. In this context the international scientific community is continuously struggling to develop better strategies in screening, diagnosing and treating hypertension and its deleterious effects. Thus, this field is continuously changing, with new important information being added constantly. A part of the book dedicated to diagnostics, comprising a chapter on new perspectives on multimodality imaging and a special chapter on diastolic dysfunction. The arrhythmic complications of hypertensive heart disease are discussed in two chapters on atrial fibrillation and ventricular arrhythmias respectively. Readers will also find new chapters regarding hypertension and heart failure in special populations such as cancer patients, young patients, pregnancy and patients with a history of SARS-CoV2 infection. This book is a useful tool for clinicians but also to the research community interested in heart failure and consequences of hypertension on heart who want to be up-to-date with the new developments in the field.

The book provides a comprehensive overview of the medical implications, pathophysiology, and treatment of Obstructive Sleep Apnea (OSA), a disease that creates increased health risks, most notably those related to the cardiovascular and cerebrovascular systems.The opening chapters are dedicated to the definition of OSA, its diagnosis, and the treatment options. The following chapters address primary forms of disease presentation in each medical field, with the latest evidence.Given its characteristics, the book will enable the reader to adopt a broad strategy for evaluating and managing OSA patients. In addition, it will be a valuable resource for all the clinicians who treat sleep-disordered breathing, including otolaryngologists, pulmonologists, cardiologists, neurologists, etc.

Hypertension: New Frontiers-A Textbook of Cardiology, is the first publication of its kind in the form of a Textbook of Cardiology from India to the world. Various sections of the book including Clinical, Diagnostic Methodology, Echocardiography, Hypertension to Heart Failure, Hypertension to Stroke, Hypertension and Aorta, Hypertension and Renovascular Diseases, Hypertension and Intervention, Hypertension and Carotid Artery Disease, Hypertension and Peripheral Vascular Disease, Clinical Management Strategies, Pediatric Cardiology, Metabolic Syndrome and Hypertension, Nutrition and Hypertension, Cardio-oncology and Hypertension, Systematic Inflammatory Release Syndrome with Resistant Hypertension, ECMO and Hypertension, Rehabilitation, and Future Directions.

This ambitious and comprehensive handbook represents an essential contribution to our current understanding of interactions between heart and brain, a research topic generating growing interest. Despite the increasing awareness that neural mechanisms are the primary cause of cardiac disease and its progression, therapy continues to focus on end-organ protection and does not approach the neural core of the problem. Growing public health problems such as heart failure are still treated with autonomic drugs that are 30-40 years old and simply act on cardiac receptors. However, it has now been shown that the progression of ischemic heart disease to heart failure is mainly due to abnormal central responses to incipient cardiac disease, with neural activation the primary cause rather than the consequence of cardiac remodeling. Written by leading international experts in their respective research areas, the book presents a variety of perspectives on the coretopic: from social and philosophical to gender-related aspects.It is designed for a broad readership and includes dedicated sections for cardiologists, psychiatrists, neurologists and psychotherapists looking for a more insightful and targeted approach to neuro-cardiovascular disease.

Advances and innovations in heart failure is the first publication in the form of a Textbook of Cardiology. Over 250 contributors from India and abroad have contributed chapters in this book. Focuses on every aspect of cardiovascular imaging and intervention, thereby enhancing knowledge and has tremendous innovative and research potential of understanding advances and innovations in heart failure for the undergraduates, postgraduates, practicing cardiologists, endocrinologists, nephrologists, neurologists, critical care, pulmonologists, pediatricians, pediatric surgeons, physicians, cardiovascular surgeons, imaging experts and nutritionists, etc. Various sections of this book include Chapter on Clinical, Echo, Imaging, Coronary artery disease, Stroke, Arrhythmia, Hypertension, Valvular, Congenital heart disease, Metabolic, Nutritional, Cardio-oncology, Inflammatory disorders and heart failure including Rehabilitation, Legal and ethical issues and Future directions, etc.

This book focuses on Cardiodiabetes Update: A Textbook of Cardiology. In the world, the scenario of prevalence of cardiometabolic syndrome varies from 60–90%. The prevalence of cardiometabolic syndrome in India varies from 40–65% and is prevalent, to a large extent, in Punjab and Kerala, in India. The prevalence rate of central obesity in the cardiometabolic syndrome varies from 80–90%; and, hypertension 70–80%. The rising menace of this hidden medical terrorist has reached pandemic proportions worldwide. It is a predictor of premature abnormal ‘cardiovascular thrombo-inflammatory chain'. It comprises nine sections, including clinical spectrum, diagnosis, management strategies, nutraceutical and obesity care, arrhythmia management, intervention, cardiac surgery, rehabilitation, and future directions, including a total of 132 chapters. Each chapter addresses a separate and distinct issue of clinical relevance. The chapters are well-outlined, organized, well-written and referenced. The writing style of every chapter is vivid, concise and practical. There are excellent graphics, tables and figures and flow charts that present the relevant information. The printing and binding is of excellent quality. This book serves as an important reference guide for the postgraduate students, fellows, internists, cardiologists, endocrinologists, nephrologists, neurologists, critical care physicians, pulmonologists, pediatricians, pediatric surgeons, cardiovascular surgeons, dermatologists, gynecologists, imaging experts and nutritionists, etc.

GAIN A GREATER UNDERSTANDING OF CARDIOVASCULAR MEDICINE – AND SHARPEN YOUR BOARD PREPARATION SKILLS -- WITH THE ONLY REVIEW BASED ON THE CONTENT OF HURST'S THE HEART Cardiology Board Review and Self-Assessment is an all-inclusive study guide and learning tool written to complement the Fourteenth Edition of Hurst's the Heart – the field's cornerstone text, and the resource considered by many to be the pinnacle of cardiovascular knowledge. Cardiology Board Review and Self-Assessment contains more than 1,100 carefully selected questions and answers presented in multiple-choice format. Each of the 112 chapters of Hurst's the Heart is represented in this unique review, with ten multiple-choice questions. Detailed answers are provided for each question, including not only an explanation of why the correct answer is correct, but also why the incorrect answers are incorrect. HERE'S WHY THIS IS THE ULTIMATE BOARD REVIEW AND CARDIOLOGY LEARNING TOOL: •Questions and answers correspond to appropriate sections of Hurst's the Heart, and include valuable tables, figures, images, and references•The more than 1,100 Q&A span the depth and breadth of the entire field of cardiovascular medicine•High-yield material is specifically selected for Board relevance •Includes content based on ACC, AHA, and ESC guidelines Cardiology Board Review and Self-Assessment: A Companion Guide to Hurst's the Heart is essential reading for anyone preparing to take the Subspecialty Examination in Cardiovascular Disease given by the Board of Internal Medicine, as well as practicing cardiologists preparing for recertification. It is also of value to medical students, residents, fellows, practicing physicians, and other healthcare professionals who wish to expand their knowledge of cardiovascular medicine.

Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. - Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information - Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress - Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes

This highly illustrated textbook has been prepared by the Working Group on Development, Anatomy and Pathology of the European Society of Cardiology (ESC). The ESC Textbook of Cardiovascular Development is the authority on cardiovascular development from a perspective of both basic scientists and clinicians. The embryonic origin of congenital heart diseases and their pathology has been analysed in depth. Modern concepts pivotal to the understanding of cardiovascular morphogenesis, including those still subject to controversy, have been highlighted and the content covers the ESC Core Curriculum. The textbook will appeal to researchers and clinicians from a wide spectrum of disciplines including molecular and developmental biologists working on mechanisms of heart development in a range of model organisms as well as pathologists, morphologists, geneticists, and cardiologists.

This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair.Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged.The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

This book provides comprehensive analysis into individualized patient care, and applying evidence‐based medicine while integrating basic medical knowledge with applied medicine. The Editor and the contributors not only discuss important issues on hypertension management and its deleterious consequences if it is not well‐controlled, but also highlight the important signaling pathways involved in the pathogenesis of hypertensive heart disease and cardiac hypertrophy.

The 9th edition of the gold standard in pediatric cardiology offers up-to-date, comprehensive coverage of this challenging and rapidly changing field. New chapters based on reader requests, two new associate editors, new contributing authors, and an enhanced digital version of the text make Moss and Adams'Heart Disease in Infants, Children, and Adolescents the reference you'll turn to when caring for patients. From cover to cover, this award-winning two-volume resource provides the authoritative, state-of-the-art information you need when caring for young patients with heart disease. New, reader-requested chapters cover Development of Myocardial Structure and Function, Global Challenge of Heart Disease, Impact of Congenital Heart Disease on Other Organ Systems, Non-Compaction Cardiomyopathy, Beyond the Cardiac Device, and Transition to Adult Care. All chapters have been updated and revised, including vital new information on genetics and embryo development. Two new associate editors, Drs. Daniel J. Penny and Frank Cetta, offer fresh perspectives in their areas of expertise. Enhanced digital access includes the full text; bonus question and answer sections similar to those on the pediatric cardiology board examination; videos of echoes, angiograms, aortic arch anomalies, open-heart operations, and more; and phonocardiograms with accompanying audio of various heart sounds and murmurs.

This book provides comprehensive insights into congenital heart disease from embryonic development through to clinical features, including human genetics and our current knowledge of the underlying molecular pathways. It is divided into three parts: an introduction to the development of the heart and its vessels, an overview of the molecular pathways affecting the development of various cardiovascular structures, and a main section focusing on the different types of structural and nonstructural congenital heart diseases, including their clinical features, underlying genetic alterations and related animal models and pathways. Taken together these chapters, which were written by and for clinicians and researchers, provide an integrated and cutting-edge resource for all those who want to learn more about both the clinical aspects and the genetic and molecular basis of congenital heart disease.

Lead editor of Braunwald's Heart Disease, Dr. Douglas L. Mann, and nationally and internationally recognized heart failure expert Dr. G. Michael Felker, bring you the latest, definitive state-of-the art information on heart failure in this outstanding Braunwald's companion volume. Heart Failure, 3rd Edition keeps you current with recent developments in the field, improved patient management strategies, and new drug therapies and implantable devices that will make a difference in your patients'lives and your practice.

Ischemic heart disease is the leading cause of morbidity and mortality in the developed world. The high metabolism and oxygen demand of the cardiac myocardium depends on both a high blood flow and a rich capillary density. For this reason, the growth of the coronary vasculature is vital, not only in early development, but also in the adult faced with various stresses. Novel technologies have enabled the discovery of the molecular mechanisms underlying the growth and assembly coronary vessels, and this volume covers the hierarchy of the coronary vasculature from its embryonic origins through its postnatal growth, adulthood, and senescence. Chapters address normal coronary development, coronary anomalies and their possible underlying developmental errors, coronary vessel adaptations to exercise training, aging, hypoxia, myocardial ischemia, and cardiac hypertrophy.This comprehensive overview of current research in coronary vessels and myocardial perfusion was written by Dr. Robert J. Tomanek, Emeritus Professor of Anatomy and Cell Biology at the University of Iowa. The book reviews, discusses, and integrates findings from various areas of coronary vasculature research, and as a result, will be a valuable reference source for cardiovascular scientists and physicians for many years to come.

To achieve cardiac regeneration using pluripotent stem (iPS) cells, researchers must understand iPS cell generation methods, cardiomyocyte differentiation protocols, cardiomyocyte characterization methods, and tissue engineering. This book presents the current status and future possibilities in cardiac regeneration using iPS cells. Written by top r

With advances and breakthroughs in modern medicine that are allowing people to live longer, the number of older adults will continue to grow exponentially over the next several decades. Cardiologists, geriatricians, and other clinicians caring for the elderly will require—at the very least—a basic understanding of cardiovascular disorders that commonly affect the older patient. In the fifth edition of Tresch and Aronow's Cardiovascular Disease in the Elderly, each chapter has been thoroughly updated to provide a comprehensive, yet accessible overview of the epidemiology, pathophysiology, evaluation, and treatment of cardiovascular disorders in older adults. The book spans topics such as aging changes in the cardiovascular system, risk factors and epidemiology for coronary artery disease, valvular heart disease, cardiomyopathies and heart failure, arrhythmias, cerebrovascular disease, and other miscellaneous subjects. The contributors supply evidence-based recommendations with strong emphasis on new research findings. New to the Fifth Edition: Numerous chapters comprehensively revised with new authors and/or co-authors Summaries at the beginning of each chapter to facilitate easy reading Discussion of the use of new antithrombotic agents in older adults Important references in the bibliography highlighted for simplified access With contributions from recognized experts in the field, this classic work continues to serve as the premier source on the evaluation and management of cardiovascular disorders in older adults.

The heart is invested with a complex, intertwining network of blood and lymphatic vessels which, respectively, provide the cardiac tissue with oxygen and nutrients and eliminate excess fluid from the interstitium. The coronary blood vessels have been the focus of much investigation in the past few decades. On the other hand, the literature regarding the cardiac lymphatic vessels remains sparse, despite their important role in maintaining normal heart function. With this in mind, a better understanding of the cardiac lymphatic network and its ability to regulate fluid homeostasis within the heart could give us insight into developing therapies for the alleviation of several cardiac pathological conditions.

This book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation. Particular attention is paid to the still underestimated adaptive cardiac responses during development, to adaptation to the frequently occurring pressure and volume overload as well as to cardiac changes, induced by enduring exercise and chronic hypoxia. Cardiac Adaptations will be of great value to cardiovascular investigators, who will find this book highly useful in their cardiovascular studies for finding solutions in diverse pathological conditions; it will also appeal to students, fellows, scientists, and clinicians interested in cardiovascular abnormalities.

Injured mammalian hearts do not regenerate but scar. This is a major medical problem, as ischemic heart disease is among the leading causes of morbidity and mortality worldwide. Essential clues for human heart repair are uncovered when zebrafish and newt are found to regenerate cardiac muscle after injury.This book presents the major advances of the last decade in the field of cardiac regeneration. These recent advances include: demonstration that zebrafish, a genetically tractable system, can regenerate heart; the identification of several new stem cell populations in the heart; demonstration that stem cells can be used to improve heart function; and demonstration that induction of cardiomyocyte proliferation is a realistic future option to repair injured hearts. This book also provides detailed reviews of the research on model organisms capable of heart regeneration as well as innovative translational research to achieve regeneration in mammals, that comprises work on blood born stem cells, endogenous cardiac stem cells, paracrine factors, reawakening of cardiomyocyte proliferation, and bioengineering. More importantly, the book, in the concluding chapter, dovetails the studies with a comprehensive overview of clinical trials.

The first edition of this text, edited by two of the world's most respected pediatric cardiologists, set the standard for a single-volume, clinically focused textbook on this subject. This new edition, revised and updated by contributors representing today's global thought leaders, offers increased coverage of the most important current topics, such as pediatric electrophysiology, congenital heart disease, cardiovascular genetics/genomics, and the identification and management of risk factors in children, while maintaining the clinical focus. Published with a companion website that features additional images for download, self-assessment questions designed to aid readers who are preparing for examinations, and other features, Pediatric Cardiovascular Medicine, Second Edition, is the perfect reference for residents, fellows, pediatricians, as well as specialists in pediatric cardiology.

Therapy in cardiology has advanced enormously in recent years. This has resulted in the organization of many meetings and the publication of numerous books dedicated to examining the latest aspects of, for instance, pharmacolog­ ic, electrical and surgical treatment. However, only a few of these meetings and publications have attempted to present an overall review of all advances that have taken place in the field of therapy. In the last years the Spanish Society of Cardiology has shown a great interest in the continuous medical education in cardiology. The Society has organized various meetings and has published several books on the above-mentioned topics. Consequently, the Society has decided to publish this book, an update of the therapeutics in cardiology, of which a Spanish version is also available. World renowned experts and outstanding Spanish cardiologists were invited to review all aspects of therapy in cardiology. We would like to thank the Spanish Society of Cardiology and the Catalan Cardiac Society for the generous assistance they have given us during all stages of book preparation. We also would like to express our appreciation to all the authors for their valuable contributions. Their combined efforts enable us to put this volume in the hands of the reader.

The most salient feature of the infor­ last four chapters of the book evaluate the mation provided by nuclear medicine is its information from an analytical and pathophysiological and functional charac­ statistical point of view. This approach is ter. For adequate experimental or clinical required for correct decision-making. interpretation, such information should This book is therefore the result of necessarily be interpreted alongside the accumulated experience in nuclear cardiology views of the clinical cardiologist, who is with the invaluable cooperation of medical able to apply it to the individual patient. statisticians. It is directed to physicians This approach, which is routine in every­ with an interest in nuclear cardiology, to day clinical practice, reaches its plenitude nuclear medicine specialists wishing to when the whole process is completed and learn the uses and limitations of these an intimate cooperation is established procedures in everyday clinical cardiology, between the nuclear medicine specialist and to cardiologists who feel the need to and the clinical cardiologist. In such understand the rationale and methodology instances, each one of these professionals of the studies which benefit their patients. understands the needs, limits and possi­ We understand that the ultimate reason bilities of the other. for any scientific book is the transmission The present book is the fruit of such of knowledge, and we are fully conscious cooperation. In our hospital, an efficient of the enthusiasm of the authors of the nuclear cardiology team has been made up present text to achieve that aim.

The clinical use of nuclear cardiology for the assessment of myocardial ischemia continues to grow at an unprecedented rate. Part of the reason for this growth is the technical advances in single photon emission computerized tomography (SPECT). SPECT has been shown to provide high contrast images superior to planar imaging techniques. An important and recent technical advancement in SPECT has been ECG-gated myocardial perfusion SPECT to generate simultaneous myocardial perfusion and function information from a single study. Automated, quantitative techniques have facilitated the widespread application of this breakthrough. Another recent advancement has been the use of attenuation correction techniques to help remove the effects of the physical phenomena that degrades the visual and quantitative accuracy of SPECT images. Another reason for the growth of the clinical use of nuclear cardiology is the large body of published evidence documenting the effectiveness of SPECT techniques for assessing myocardial ischemia, myocardium at risk, viable myocardium and stunned or hibernating myocardium. These assessments have been shown to be important not only in diagnosis but also in prognosis. This book is divided into three major sections, each addressing the important topics of nuclear cardiology. The first section is a that have led to the clinical success description of the technical aspects of state-of-the-art myocardial perfusion SPECT imaging. This section deals with the radionuclides, instrumentation, image acquisition and analysis, interpretation and quantification techniques used in the most progressive nuclear cardiology clinics.

Coronary Heart Disease: Clinical, Pathological, Imaging, and Molecular Profiles presents a comprehensive picture of ischemic heart disease for practitioners, students, and investigators dealing with the varied facets of this complex subject. Individual chapters introduce the anatomy of the coronary blood vessels and cardiac development, while others consider current imaging modalities utilized for ischemic heart disease, including stress echo, nuclear diagnostic tests, non-invasive coronary artery imaging, and coronary angiography. Imaging chapters provide key clinical information on techniques and indications, and include examples of both normal and abnormal patterns. The principle thrust of the book concerns coronary atherosclerosis, the pathology of which is presented in conjunction with the results of anatomic, non-invasive imaging and angiographic studies. Related chapters cover atherogenesis, presenting new insights into the pathophysiology of the vulnerable plaque, the role of progenitor cells in vascular injury, inflammation and atherogenesis, and the genomics of vascular remodeling. Additional topics covered include angina pectoris, acute coronary syndromes, healed myocardial infarction and congestive heart failure, catheter-based and surgical revascularization, and surgical treatment of myocardial infarction and its sequelae. With contributions from a diverse group of internationally-known physicians with broad experience in the diagnosis and treatment of coronary heart disease, this book will be a valuable resource for practitioners in clinical cardiology, thoracic surgery, pathology, and cardiovascular molecular research, as well as for students in training.

Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact. This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.

Congenital Heart Defects, or CHDs, are the most frequently occurring birth defect. In the US alone, over 25,000 babies are born each year with some form of CHD. In the last 20 years, medical advances and new surgical procedures have dramatically decreased the mortality rate of these abnormalities and led to a better understanding and treatment of CHDs in adults. This definitive work on the subject covers all aspects of CHD, under the editorship of a leading geneticist, cardiologist, and public health physician, and features contributions from 60 major authorities in the field. Coverage includes a broad range of topics on the development, epidemiology, genetics, diagnosis, management, prevention, and public health issues of CHDs. This book will be of interest to geneticists, epidemiologists, cardiologists, pediatricians, graduate students, researchers, and others interested in the treatment of individuals with CHDs.

Accounting for the huge strides in technological development over the past few years, as well as of recent research and advances, this text updates cutting-edge information on topics such as: embryologycardiovascular developmentplacental implantation and developmentintracardiac shunt malformationsfetal cardiac tumorsNEW TO THE SECOND EDITION:downloadable resources with over 50 video clips, including 4D ultrasoundhigh quality illustrations in colour throughoutnew information on the cardiac impact of twin-twin transfusion syndrome, cerebral outcomes in CHD, and congestive heart failure

Acute heart failure is a potentially life threatening situation where correct, rapid therapy can have a life saving impact. In this rapidly changing area of medicine this text aims to bring the latest understanding of the pathophysiology together with a practical guide to diagnosis and management using a thoroughly evidence based approach. This will appeal to a wide audience of health care professionals who will treat patients with acute heart failure, including doctors, medical students, nurses, and other professionals in the Emergency Department, General Internal Medicine, Anaesthetics, Cardiology (Medicine and Surgery) and Critical Care settings. It may be used as an evidence based guide for the junior practitioner or as an aide-memoire for the more senior. Always keeping the underlying pathophysiology at the forefront of the discussion, the reader is encouraged to understand the aetiology of the acute situation and how to direct management in order to correct the abnormal physiology. Each chapter is heavily referenced allowing the reader to easily refer to the original experimental studies and pursue topics in more detail if required. This text is a valuable addition to any practitioner who treats patients with acute heart failure and wants a deeper understanding of the condition.

Individuals 65 years of age or older currently account for over eighty percent of all cardiovascular disease-related deaths. With advances and breakthroughs in modern medicine that are allowing people to live longer, the number of older adults in this country will continue to grow exponentially over the next several decades. Cardiologists, geriatri

This reference thoroughly equips you to successfully diagnose and manage even the most complex incidences of diastolic heart failure and their comorbidities. It examines the basic mechanisms of this condition through discussions of both cellular and anatomic causes; guides you through non-invasive techniques for diagnosis, including echocardiography, cardiac CT, and MRI; and provides expert advice on pharmacologic management.Covers the basic mechanisms of diastolic heart problems from both cellular and anatomic perspectives. Chapters covering modalities helpful in assessment of diastolic function such as: echocardiography, cardiac MRI, radionuclide ventriculography, and invasive hemodynamic measurements. Features in-depth assessments of all diagnostic methods for diastolic heart failure, including rationales for their use. Examines contributing conditions that play a role in diastolic heart failure and offers guidance on their management. Offers pharmacologic strategies for multiple problem management.

Revascularization of the heart is the prime objective following a myocardial infarction as the morbidity inflicted severely impacts the patient's lifestyle and working capabilities. The use of stem cell transplantation is one route that is receiving considerable funding from government and private sources. This book examines the various methods ava

Despite being one of the world's biggest killers of women, heart disease is under-diagnosed, under-treated, and under-managed. Why? What is going wrong?Important and ground-breaking, Women and Heart Disease brings our attention to the inadequacies in both the diagnosis and treatment of heart disease in women.Key features:• written by Nanette Wenger and Peter Collins, two of the worlds leading cardiologists• contributions from leaders in women‘s cardiac health• covers all aspects of cardiovascular disease, not just coronary artery disease• fully updated.Building on the success of the best-selling first edition, this is essential reading for all physicians with a particular interest in women and heart disease.

Questa settima edizione delle Malattie del cuore di Braunwald, punto di riferimento della moderna cardiologia, si presenta in unaveste contenutistica e grafica completamente rinnovata e ampliata.Ai 51 capitoli già esistenti, che sono stati radicalmente rivisti e aggiornati, ne sono stati aggiunti 35, scritti da 57 nuovi autori, conargomenti che spaziano dal processo decisionale in cardiologia alle manifestazioni vascolari dei disturbi autonomici,

Heart failure causes approximately 300,000 deaths each year in the United States alone. But heart failure does not always lead to death. Managing the condition is complex, and requires the clinician to be knowledgeable about the most current treatment options. This handbook examines the intricacies of managing patients with heart failure, including pharmacologic and non-pharmacologic treatment options. Special attention is given to the treatment of concurrent, perhaps precipitous, conditions such as hypertension.

Rev. ed. of: Women and heart disease. 1997.

Emphasizes the research activities of Germany's Nauheim Institute of the Max Planck Society and its group of investigators both past and present, in the field of collateral artery growth. Incorporates a multidisciplinary in vivo approach to the study of arteriogenesis that includes molecular approaches with classical physiology and immunohistochemistry. Full color throughout and well illustrated.

Certain to become the most trusted source in geriatric cardiology, this Third Edition compiles the latest studies and expertise on the epidemiology, pathophysiology, and management of cardiovascular disease in the elderly patient, tracking the rapid pace of innovation in the field with in-depth explorations of the most recent clinical trials and advances in vascular biology, cardiology, and cardiovascular surgery for influential developments in disease prevention and management.

Diabetes mellitus, particularly non-insulin-dependent diabetes Type 2, is a common disease and, even though insulin has been around for seventy years, this endocrine disorder still reduces the life expectancy of diabetic patients because of the development of long-term complications, including hypertension. Hypertension occurs twice as often in dia

Reviews the best therapies and surgical techniques available to provide quality care for the elderly cardiac patient and of those areas that require further research. The authors detail preventive therapies and the cardiovascular syndromes that disproportionately afflict the older individual, including arrhythmias (particularly atrial fibrillation), syncope, heart failure (particularly diastolic heart failure), and ischemic heart disease. They also delineate the surgical management of the heart patient with discussions of postoperative management and its complications and of specific surgical procedures such as coronary artery bypass grafting, valve surgery, pacemaker and defibibrillators, and surgical management of heart failure.

At nearly every cardiology conference, whether in Europe or in the U.S., new clinical trial data is published. At times, so much information is published that the busy clinical cardiologist does not have time to keep abreast of the latest and preferred therapies. This successive volume examines advances that have taken place since the previous vers