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This issue gives the general radiologist a solid overview of lung cancer imaging techniques. CT screening for lung cancer is discussed, and the evaluation and management of indeterminate pulmonary nodules is reviewed. Revised TNM lung cancer staging, as well as the optimal imaging protocols for lung cancer staging (CT, MR and PET) are thoroughly examined. A multidisciplinary approach to tissue sampling and updated histopathologic classification of lung cancer are discussed. Image-guided ablative therapies for lung cancer are reviewed. Finally, future trends in lung cancer diagnosis and staging and genetics are reviewed, as well as novel biomarkers for lung cancer detection.