Search

This book constitutes the proceedings of the 7th International Conference on Algorithms for Computational Biology, AlCoB 2020, was planned to be held in Missoula, MT, USA in April 2020. Due to the corona pandemic the conference was postponed to be held together with AlCoB 2021.The 15 full papers included in this volume were carefully reviewed and selected from 24 submissions. They were organized in topical sections on genomics, phylogenetics, and RNA-Seq and other biological processes.

This book constitutes the refereed proceedings of the 17th International Conference on Computational Methods in Systems Biology, CMSB 2019, held in Trieste, Italy, in September 2019.The 14 full papers, 7 tool papers and 11 posters were carefully reviewed and selected from 53 submissions. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology and parallel implementations; model inference from experimental data; model integration from biological databases; multi-scale modeling and analysis methods; computational approaches for synthetic biology; and case studies in systems and synthetic biology.

This two-volume set LNCS 10305 and LNCS 10306 constitutes the refereed proceedings of the 15th International Work-Conference on Artificial Neural Networks, IWANN 2019, held at Gran Canaria, Spain, in June 2019.The 150 revised full papers presented in this two-volume set were carefully reviewed and selected from 210 submissions. The papers are organized in topical sections on machine learning in weather observation and forecasting; computational intelligence methods for time series; human activity recognition; new and future tendencies in brain-computer interface systems; random-weights neural networks; pattern recognition; deep learning and natural language processing; software testing and intelligent systems; data-driven intelligent transportation systems; deep learning models in healthcare and biomedicine; deep learning beyond convolution; artificial neural network for biomedical image processing; machine learning in vision and robotics; system identification, process control,and manufacturing; image and signal processing; soft computing; mathematics for neural networks; internet modeling, communication and networking; expert systems; evolutionary and genetic algorithms; advances in computational intelligence; computational biology and bioinformatics.

This two-volume set LNCS 10305 and LNCS 10306 constitutes the refereed proceedings of the 15th International Work-Conference on Artificial Neural Networks, IWANN 2019, held at Gran Canaria, Spain, in June 2019.The 150 revised full papers presented in this two-volume set were carefully reviewed and selected from 210 submissions. The papers are organized in topical sections on machine learning in weather observation and forecasting; computational intelligence methods for time series; human activity recognition; new and future tendencies in brain-computer interface systems; random-weights neural networks; pattern recognition; deep learning and natural language processing; software testing and intelligent systems; data-driven intelligent transportation systems; deep learning models in healthcare and biomedicine; deep learning beyond convolution; artificial neural network for biomedical image processing; machine learning in vision and robotics; system identification, process control,and manufacturing; image and signal processing; soft computing; mathematics for neural networks; internet modeling, communication and networking; expert systems; evolutionary and genetic algorithms; advances in computational intelligence; computational biology and bioinformatics.

This book constitutes the proceedings of the 6th InternationalConference on Algorithms for Computational Biology, AlCoB 2019, held in Berkeley, CA, USA, in May 2019. The 15 full papers presented together with 1 invited paper were carefully reviewed and selected from 30 submissions. They are organized in the following topical sections: Biological networks and graph algorithms; genome rearrangement, assembly and classification; sequence analysis, phylogenetics and other biological processes.

This book constitutes the thoroughly refereed post-conference proceedings of the 14th International Meeting on Computational. Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2017, held in Cagliari, Italy, in September 2017.The 19 revised full papers presented were carefully reviewed and selected from 44 submissions. The papers deal with the application of computational intelligence to open problems in bioinformatics, biostatistics, systems and synthetic biology, medical informatics, computational approaches to life sciences in general.

This book constitutes the thoroughly refereed post-conference proceedings of the 13th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2016, held in Stirling, UK, in September 2016. The 19 revised full papers and 6 keynotes abstracts presented were carefully reviewed and selected from 61 submissions. The papers deal with the application of computational intelligence to open problems in bioinformatics, biostatistics, systems and synthetic biology, medicalinformatics, computational approaches to life sciences in general

This book explains the state-of-the-art algorithms used to simulate biological dynamics. Each technique is theoretically introduced and applied to a set of modeling cases. Starting from basic simulation algorithms, the book also introduces more advanced techniques that support delays, diffusion in space, or that are based on hybrid simulation strategies.This is a valuable self-contained resource for graduate students and practitioners in computer science, biology and bioinformatics. An appendix covers the mathematical background, and the authors include further reading sections in each chapter.

This book develops a new approach called parameter advising for finding a parameter setting for a sequence aligner that yields a quality alignment of a given set of input sequences. In this framework, a parameter advisor is a procedure that automatically chooses a parameter setting for the input, and has two main ingredients: (a) the set of parameter choices considered by the advisor, and (b) an estimator of alignment accuracy used to rank alignments produced by the aligner. On coupling a parameter advisor with an aligner, once the advisor is trained in a learning phase, the user simply inputs sequences to align, and receives an output alignment from the aligner, where the advisor has automatically selected the parameter setting. The chapters first lay out the foundations of parameter advising, and then cover applications and extensions of advising. The content • examines formulations of parameter advising and their computational complexity, • develops methods for learning good accuracy estimators, • presents approximation algorithms for finding good sets of parameter choices, and • assesses software implementations of advising that perform well on real biological data. Also explored are applications of parameter advising to • adaptive local realignment, where advising is performed on local regions of the sequences to automatically adapt to varying mutation rates, and • ensemble alignment, where advising is applied to an ensemble of aligners to effectively yield a new aligner of higher quality than the individual aligners in the ensemble. The book concludes by offering future directions in advising research.

This book constitutes the refereed proceedings of the 23th International Conference on DNA Computing and Molecular Programming, DNA 23, held Austin, TX, USA, in September 2017. The 16 full papers presented were carefully selected from 23 submissions. Research in DNA computing aims to draw together mathematics, computerscience, physics, chemistry, biology, and nanotechnology to address the analysis, design, and synthesis of information-based molecular systems. The papers address all areas related to biomolecular computing such as: algorithms and models for computation with biomolecular systems; computational processes in vitro and in vivo; molecular motors and molecular robotics; studies of fault-tolerance and error correction; software tools for analysis, simulation, and design; synthetic biology and in vitro evolution; applications in engineering, physics, chemistry, biology, and medicine.

This book constitutes the proceedings of the 4th InternationalConference on Algorithms for Computational Biology, AlCoB 2017, held in Aveiro, Portugal, in June 2017. The 10 full papers presented together with 2 invited papers were carefully reviewed and selected from 24 submissions. They are organized in the following topical sections: Graph Algorithms for Computational Biology; Phylogenetics; and Sequence Analysis and Other Biological Processes.

This book constitutes the refereed proceedings of the 14th International Conference on Parallel Problem Solving from Nature, PPSN 2016, held in Edinburgh, UK, in September 2016. The total of 93 revised full papers were carefully reviewed and selected from 224 submissions. The meeting began with four workshops which offered an ideal opportunity to explore specific topics in intelligent transportation Workshop, landscape-aware heuristic search, natural computing in scheduling and timetabling, and advances in multi-modal optimization. PPSN XIV also included sixteen free tutorials to give us all the opportunity to learn about new aspects: gray box optimization in theory; theory of evolutionary computation; graph-based and cartesian genetic programming; theory of parallel evolutionary algorithms; promoting diversity in evolutionary optimization: why and how; evolutionary multi-objective optimization; intelligent systems for smart cities; advances on multi-modal optimization; evolutionary computation in cryptography; evolutionary robotics - a practical guide to experiment with real hardware; evolutionary algorithms and hyper-heuristics; a bridge between optimization over manifolds and evolutionary computation; implementing evolutionary algorithms in the cloud; the attainment function approach to performance evaluation in EMO; runtime analysis of evolutionary algorithms: basic introduction; meta-model assisted (evolutionary) optimization. The papers are organized in topical sections on adaption, self-adaption and parameter tuning; differential evolution and swarm intelligence; dynamic, uncertain and constrained environments; genetic programming; multi-objective, many-objective and multi-level optimization; parallel algorithms and hardware issues; real-word applications and modeling; theory; diversity and landscape analysis.

This book constitutes the thoroughly refereed post-conference proceedings of the 12th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2015, held in Naples, Italy, in September, 2015. The 21 revised full papers presented were carefully reviewed and selected from 24 submissions. They present problems concerning computational techniques in bioinformatics, systems biology and medical informatics discussing cutting edge methodologies and accelerate life science discoveries, as well as novel challenges with an high impact on molecular biology and translational medicine.

This book constitutes the refereed proceedings of the 22nd International Conference on DNA Computing and Molecular Programming, DNA 22, held Munich, Germany, in September 16The 11 full papers presented together with 10 invited and tutorial talks were carefully selected from 55 submissionsResearch in DNA computing and molecular programming draws together mathematics, computer science, physics, chemistry, biology, and nanotechnology to address the analysis, design, and synthesis of information-based molecular systems

This book constitutes the proceedings of the Third InternationalConference on Algorithms for Computational Biology, AlCoB 2016, held inTrujillo, Spain, in June 2016.The 13 full papers presented in this volume were carefully reviewed andselected from 23 submissions. They are organized in the following topical sections: biological networks and modelling; biological structure processing; phylogenetics; and sequence analysis and rearrangement. In addition one invited talk is included.

This book constitutes the proceedings of the 20th Annual Conference on Research in Computational Molecular Biology, RECOMB 2016, held in Santa Monica, CA, USA, in April 2016. The 15 regular papers presented in this volume were carefully reviewed and selected from 172 submissions. 20 short abstracts are included in the back matter of the volume. They report on original research in all areas of computational molecular biology and bioinformatics.

This book constitutes the refereed proceedings of the 12th Conference on Computability in Europe, CiE 2016, held in Paris, France, in June/July 2016. The 18 revised full papers and 19 invited papers and invited extended abstracts were carefully reviewed and selected from 40 submissions. The conference CiE 2016 has six special sessions – two sessions, cryptography and information theory and symbolic dynamics, are organized for the first time in the conference series. In addition to this new developments in areas frequently covered in the CiE conference series were addressed in the following sessions: computable and constructive analysis; computation in biological systems; history and philosophy of computing; weak arithmetic.

This book constitutes the refereed proceedings of the 16th International Workshop on Algorithms in Bioinformatics, WABI 2016, held in Aarhus, Denmark. The 25 full papers together with 2 invited talks presented were carefully reviewed and selected from 54 submissions.The selected papers cover a wide range of topics from networks, tophylogenetic studies, sequence and genome analysis, comparative genomics, and mass spectrometry data analysis.

This book constitutes the thoroughly refereed post-conference proceedings of the 7th International Conference on Trusted Systems, INTRUST 2015, held in Beijing, China, in December 2015. The revised 12 full papers presented have been carefully reviewed and selected from 29 submissions. They are devoted to all aspects of trusted computing systems, including trusted modules, platforms; networks, services and applications. The papers are organized in the following sections: encryptions and signatures; security model; trusted technologies; software and system security.

This volume contains the post-conference proceedings of the 10th Doctoral Workshop on Mathematical and Engineering Methods in Computer Science, MEMICS 2015, held in Telč, Czech Republic, in October 2015.The 10 thoroughly revised full papers were carefully selected out of 25 submissions and are presented together with 3 invited papers. The topics covered include: security and safety, bioinformatics, recommender systems, high-performance and cloud computing, and non-traditional computational models (quantum computing, etc.).

This book constitutes the thoroughly refereed post-workshop proceedings for the 26 International Workshop on combinatorial Algorithms, IWOCA 2015, held in Verona, Italy, in October 2015.The 29 revised full papers presented were carefully reviewed and selected from a total of 90 submissions. The topics of the papers include algorithms and data structures (including sequential, parallel, distributed, approximation, probabilistic, randomised, and on-line algorithms), algorithms on strings and graphs; applications (bioinformatics, music analysis, networking, and others); combinatorics on words; combinatorial enumeration; combinatorial optimization; complexity theory; computational biology; compression and information retrieval; cryptography and information security; decompositions and combinatorial designs; discrete and computational geometry; graph drawing and labeling; graph theory.

This book constitutes the refereed proceedings of the 19th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2015, held in Warsaw, Poland, in April 2015. The 36 extended abstracts were carefully reviewed and selected from 170 submissions. They report on original research in all areas of computational molecular biology and bioinformatics.

The two volumes LNCS 9107 and 9108 constitute the proceedings of the International Work-Conference on the Interplay Between Natural and Artificial Computation, IWINAC 2015, held in Elche, Spain, in June 2015.The total of 103 contributions was carefully reviewed and selected from 190 submissions during two rounds of reviewing and improvement. The papers are organized in two volumes, one on artificial computation and biology and medicine, addressing topics such as computational neuroscience, neural coding and neuro-informatics, as well as computational foundations and approaches to the study of cognition. The second volume deals with bioinspired computation in artificial systems; topics alluded are bio-inspired circuits and mechanisms, bioinspired programming strategies, and bioinspired engineering AI&KE.

The two volumes LNCS 9107 and 9108 constitute the proceedings of the International Work-Conference on the Interplay Between Natural and Artificial Computation, IWINAC 2015, held in Elche, Spain, in June 2015.The total of 103 contributions was carefully reviewed and selected from 190 submissions during two rounds of reviewing and improvement. The papers are organized in two volumes, one on artificial computation and biology and medicine, addressing topics such as computational neuroscience, neural coding and neuro-informatics, as well as computational foundations and approaches to the study of cognition. The second volume deals with bioinspired computation in artificial systems; topics alluded are bio-inspired circuits and mechanisms, bioinspired programming strategies and bioinspired engineering AI&KE.

This book constitutes the refereed proceedings of the 26th Annual Symposium on Combinatorial Pattern Matching, CPM 2015, held on Ischia Island, Italy, in June/July 2015.The 34 revised full papers presented together with 3 invited talks were carefully reviewed and selected from 83 submissions. The papers address issues of searching and matching strings and more complicated patterns such as trees; regular expressions; graphs; point sets; and arrays. The goal is to derive combinatorial properties of such structures and to exploit these properties in order to achieve superior performance for the corresponding computational problems. The meeting also deals with problems in computational biology; data compression and data mining; coding; information retrieval; natural language processing; and pattern recognition.

This book constitutes the refereed proceedings of the 11th Conference on Computability in Europe, CiE 2015, held in Bucharest, Romania, in June/July 2015.The 26 revised papers presented were carefully reviewed and selected from 64 submissions and included together with 10 invited papers in this proceedings. The conference CiE 2015 has six special sessions: two sessions, Representing Streams and Reverse Mathematics, were introduced for the first time in the conference series. In addition to this, new developments in areas frequently covered in the CiE conference series were addressed in the further special sessions on Automata, Logic and Infinite Games; Bio-inspired Computation; Classical Computability Theory; as well as History and Philosophy of Computing.

This book constitutes the refereed proceedings of the 15th International Workshop on Algorithms in Bioinformatics, WABI 2015, held in Atlanta, GA, USA, in September 2015. The 23 full papers presented were carefully reviewed and selected from 56 submissions. The selected papers cover a wide range of topics from networks to phylogenetic studies, sequence and genome analysis, comparative genomics, and RNA structure.

Normal 0 false false false EN-US X-NONE X-NONE /• Style Definitions •/ table.MsoNormalTable {mso-style-name:'Table Normal'; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:''; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:'Calibri','sans-serif'; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:'Times New Roman'; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:'Times New Roman'; mso-bidi-theme-font:minor-bidi;} This book constitutes the revised selected papers of the First International Workshop on Machine Learning in Medical Imaging, MLMMI 2015, held in July 2015 in Lille, France, in conjunction with the 32nd International Conference on Machine Learning, ICML 2015. The 10 papers presented in this volume were carefully reviewed and selected for inclusion in the book. The papers communicate the specific needs and nuances of medical imaging to the machine learning community while exposing the medical imaging community to current trends in machine learning.

This book constitutes the refereed proceedings of the 21st International Conference on DNA Computing and Molecular Programming, DNA 21, held in Boston and Cambridge, MA, USA, in August 2015.The 13 full papers presented were carefully selected from 63 submissions. The papers address all current issues related to biomolecular computing, such as: algorithms and models for computation on biomolecular systems; computational processes in vitro and in vivo; molecular switches, gates, devices, and circuits; molecular folding and self-assembly of nanostructures; analysis and theoretical models of laboratory techniques; molecular motors and molecular robotics; studies of fault-tolerance and error correction; software tools for analysis, simulation, and design; synthetic biology and in vitro evolution; applications in engineering, physics, chemistry, biology, and medicine.

This unique textbook/reference presents unified coverage of bioinformatics topics relating to both biological sequences and biological networks, providing an in-depth analysis of cutting-edge distributed algorithms, as well as of relevant sequential algorithms. In addition to introducing the latest algorithms in this area, more than fifteen new distributed algorithms are also proposed. Topics and features: reviews a range of open challenges in biological sequences and networks; describes in detail both sequential and parallel/distributed algorithms for each problem; suggests approaches for distributed algorithms as possible extensions to sequential algorithms, when the distributed algorithms for the topic are scarce; proposes a number of new distributed algorithms in each chapter, to serve as potential starting points for further research; concludes each chapter with self-test exercises, a summary of the key points, a comparison of the algorithms described, and a literature review.

This book constitutes the thoroughly refereed post-conference proceedings of the 11th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2014, held in Cambridge, UK, in June 2014.The 25 revised full papers presented were carefully reviewed and selected from 44 submissions. The papers focus problems concerning computational techniques in bioinformatics, systems biology, medical informatics and biostatistics.

This book constitutes the refereed proceedings of the 20th International Conference on Implementation and Application of Automata, CIAA 2015, held in held in Umeå, Sweden, in August 2015. The 22 revised full papers presented together with 4 invited papers and 2 toool demonstration papers were carefully reviewed and selected from 49 submissions. The papers cover all aspects of cover automata, counter automata, decision algorithms on automata, descriptional complexity, expressive power of automata, homing sequences, jumping finite automata, multi-dimensional languages, parsing and pattern matching, quantum automata, realtime pushdown automata, random generation of automata, regular expressions, security issues, sensors in automata, transducers, transformation of automata, and weighted automata.

This book constitutes the thoroughly refereed post-workshop proceedings of the 25th International Workshop on Combinatorial Algorithms, IWOCA 2014, held in Duluth, MN, USA, in October 2014. The 32 revised full papers presented were carefully reviewed and selected from a total of 69 submissions. The papers focus on topics such as Algorithms and Data Structures, Combinatorial Enumeration, Combinatorial Optimization, Complexity Theory (Structural and Computational), Computational Biology, Databases (Security, Compression and Information Retrieval), Decompositions and Combinatorial Designs, Discrete and Computational Geometry, as well as Graph Drawing and Graph Theory. IWOCA is a yearly forum for researchers in designing algorithms field to advance creativeness of intersection between mathematics and computer science. This is the first time this conference is being held in U.S.

This book constitutes the refereed proceedings of the 20th International Conference on DNA Computing and Molecular Programming, DNA 20, held in Kyoto, Japan, in September 2014. The 10 full papers presented were carefully selected from 55 submissions. The papers are organized in many disciplines (including mathematics, computer science, physics, chemistry, material science and biology) to address the analysis, design, and synthesis of information-based molecular systems.

This book constitutes the refereed proceedings of the 8th IAPR International Conference on Pattern Recognition in Bioinformatics, PRIB 2014, held in Stockholm, Sweden in August 2014. The 9 revised full papers and 9 revised short papers presented were carefully reviewed and selected from 29 submissions. The focus of the conference was on the latest Research in Pattern Recognition and Computational Intelligence-Based Techniques Applied to Problems in Bioinformatics and Computational Biology.

This book constitutes the refereed proceedings of the 14th International Workshop on Algorithms in Bioinformatics, WABI 2014, held in Wroclaw, Poland, in September 2014. WABI 2014 was one of seven conferences that were organized as part of ALGO 2014. WABI is an annual conference series on all aspects of algorithms and data structure in molecular biology, genomics and phylogeny data analysis. The 26 full papers presented together with a short abstract were carefully reviewed and selected from 61 submissions. The selected papers cover a wide range of topics from sequence and genome analysis through phylogeny reconstruction and networks to mass spectrometry data analysis.

This book constitutes the refereed proceedings of the 25th Annual Symposium on Combinatorial Pattern Matching, CPM 2014, held in Moscow, Russia, in June 2014. The 28 revised full papers presented together with 5 invited talks were carefully reviewed and selected from 54 submissions. The papers address issues of searching and matching strings and more complicated patterns such as trees; regular expressions; graphs; point sets; and arrays. The goal is to derive combinatorial properties of such structures and to exploit these properties in order to achieve superior performance for the corresponding computational problems. The meeting also deals with problems in computational biology; data compression and data mining; coding; information retrieval; natural language processing; and pattern recognition.

This book constitutes the thoroughly refereed post-conference proceedings of the 7th International Conference on Bio-Inspired Models of Network, Information and Computing Systems (Bionetics 2012), held in Lugano, Switzerland, in December 2012. The 23 revised full papers presented were carefully reviewed and selected from 40 submissions. They cover topics such as networking, robotics and neural networks, molecular scale and bioinformatics, optimization and bio-inspired modeling in various fields.

This book constitutes the refereed proceedings of the 13th International Conference on Parallel Problem Solving from Nature, PPSN 2013, held in Ljubljana, Slovenia, in September 2014. The total of 90 revised full papers were carefully reviewed and selected from 217 submissions. The meeting began with 7 workshops which offered an ideal opportunity to explore specific topics in evolutionary computation, bio-inspired computing and metaheuristics. PPSN XIII also included 9 tutorials. The papers are organized in topical sections on adaption, self-adaption and parameter tuning; classifier system, differential evolution and swarm intelligence; coevolution and artificial immune systems; constraint handling; dynamic and uncertain environments; estimation of distribution algorithms and metamodelling; genetic programming; multi-objective optimisation; parallel algorithms and hardware implementations; real world applications; and theory.

This book constitutes the thoroughly refereed post-conferenceproceedings of the 10th International Meeting on ComputationalIntelligence Methods for Bioinformatics and Biostatistics, CIBB 2013, held in Nice, France in June 2013.The 19 revised full papers presented were carefully reviewed andselected from 35 submissions. The papers are organized in topicalsections on bioinformatics, biostatistics, knowledge based medicine, and data integration and analysis in omic-science.

This book constitutes the refereed proceedings of the 19thInternational Conference on Implementation and Application of Automata, CIAA 2014, held in Giessen, Germany, in July/August 2014. The 21 revised full papers presented together with 4 invited papers were carefully selected from 36 submissions. The papers cover all aspects of implementation, application, and theory of automata and related structures such as algorithms on automata, automata and logic, bioinformatics, complexity of automata operations, compilers,computer-aided verification, concurrency, data structure design forautomata, data and image compression, design and architecture ofautomata software, digital libraries, DNA/molecular/membrane computing, document engineering, editors, environments, experimental studies and practical experience, implementation of verification methods and model checking, industrial applications, natural language and speech processing, networking, new algorithms for manipulating automata, object-oriented modeling, pattern-matching, pushdown automata and context-free grammars, quantum computing, structured and semi-structured documents, symbolic manipulation environments for automata, transducers and multi-tape automata, techniques for graphical display of automata, VLSI, viruses and related phenomena, and world-wide Web.

This book constitutes the refereed proceedings of the 9th Brazilian Symposium on Bioinformatics, BSB 2014, held in Belo Horizonte, Brazil, in October 2014. The 18 revised full papers presented were carefully reviewed and selected from 32 submissions. The papers cover all aspects of bioinformatics and computational biology.

This book constitutes the refereed proceedings of the First International Conference, AlCoB 2014, held in July 2014 in Tarragona, Spain.The 20 revised full papers were carefully reviewed and selected from 39 submissions. The scope of AlCoB includes topics of either theoretical or applied interest, namely: exact sequence analysis, approximate sequence analysis, pairwise sequence alignment, multiple sequence alignment, sequence assembly, genome rearrangement, regulatory motif finding, phylogeny reconstruction, phylogeny comparison, structure prediction, proteomics: molecular pathways, interaction networks, transcriptomics: splicing variants, isoform inference and quantification, differential analysis, next-generation sequencing: population genomics, metagenomics, metatranscriptomics, microbiome analysis, systems biology.

This book constitutes the thoroughly refereed post-conference proceedings of the 4th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2011, held in Rome, Italy, in January 2011. The 27 revised full papers presented together with one invited lecture were carefully reviewed and selected from a total of 538 submissions. The papers cover a wide range of topics and are organized in four general topical sections on biomedical electronics and devices; bioinformatics models, methods and algorithms; bio-inspired systems and signal processing; health informatics.

The 30 coherently written chapters by leading researchers presented in this anthology are devoted to basic results achieved in computational intelligence since 1997. The book provides complete coverage of the core issues in the field, especially in fuzzy logic and control as well as for evolutionary optimization algorithms including genetic programming, in a comprehensive and systematic way. Theoretical and methodological investigations are complemented by prototypic applications for design and management tasks in electrical engineering, mechanical engineering, and chemical engineering.This book will become a valuable source of reference for researchers active in computational intelligence. Advanced students and professionals interested in learning about and applying advanced techniques of computational intelligence will appreciate the book as a useful guide enhanced by numerous examples and applications in a variety of fields.

Evolutionary Algorithms, in particular Evolution Strategies, Genetic Algorithms, or Evolutionary Programming, have found wide acceptance as robust optimization algorithms in the last ten years. Compared with the broad propagation and the resulting practical prosperity in different scientific fields, the theory has not progressed as much.This monograph provides the framework and the first steps toward the theoretical analysis of Evolution Strategies (ES). The main emphasis is on understanding the functioning of these probabilistic optimization algorithms in real-valued search spaces by investigating the dynamical properties of some well-established ES algorithms. The book introduces the basic concepts of this analysis, such as progress rate, quality gain, and self-adaptation response, and describes how to calculate these quantities. Based on the analysis, functioning principles are derived, aiming at a qualitative understanding of why and how ES algorithms work.

The two volume-set, LNCS 7930 and LNCS 7931, constitutes the refereed proceedings of the 5th International Work-Conference on the Interplay between Natural and Artificial Computation, IWINAC 2013, held in Mallorca, Spain, in June 2013. The 92 revised full papers presented in LNCS 7930 and LNCS 7931 were carefully reviewed and selected from numerous submissions. The first part, LNCS 7930, entitled'Natural and Artificial Models in Computation and Biology”, includes all the contributions mainly related to the methodological, conceptual, formal, and experimental developments in the fields of neurophysiology and cognitive science. The second part, LNCS 7931, entitled “Natural and Artificial Computation in Engineering and Medical Applications”, contains the papers related to bioinspired programming strategies and all the contributions related to the computational solutions to engineering problems in different application domains, specially Health applications, including the CYTED “Artificial and Natural Computation for Health” (CANS) research network papers. In addition, this two volume-set reflects six interesting areas: cognitive robotics; natural computing; wetware computation; quality of life technologies; biomedical and industrial perception applications; and Web intelligence and neuroscience.

The two volume-set, LNCS 7930 and LNCS 7931, constitutes the refereed proceedings of the 5th International Work-Conference on the Interplay between Natural and Artificial Computation, IWINAC 2013, held in Mallorca, Spain, in June 2013. The 92 revised full papers presented in LNCS 7930 and LNCS 7931 were carefully reviewed and selected from numerous submissions. The first part, LNCS 7930, entitled'Natural and Artificial Models in Computation and Biology”, includes all the contributions mainly related to the methodological, conceptual, formal, and experimental developments in the fields of neurophysiology and cognitive science. The second part, LNCS 7931, entitled “Natural and Artificial Computation in Engineering and Medical Applications”, contains the papers related to bioinspired programming strategies and all the contributions related to the computational solutions to engineering problems in different application domains, specially Health applications, including the CYTED “Artificial and Natural Computation for Health” (CANS) research network papers. In addition, this two volume-set reflects six interesting areas: cognitive robotics; natural computing; wetware computation; quality of life technologies; biomedical and industrial perception applications; and Web intelligence and neuroscience.

This book constitutes the refereed proceedings of the 17th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2013, held in Beijing, China, in April 2013. The 32 revised full papers were carefully reviewed and selected from 167 submissions. The papers cover a wide range of topics including molecular sequence analysis; genes and regulatory elements; molecular evolution; gene expression; biological networks; sequencing and genotyping technologies; genomics; epigenomics; metagenomics; population, statistical genetics; systems biology; computational proteomics; computational structural biology; imaging; large-scale data management.

This book constitutes the refereed proceedings of the 11th European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics, EvoBIO 2013, held in Vienna, Austria, in April 2013, colocated with the Evo• 2013 events EuroGP, EvoCOP, EvoMUSART and EvoApplications. The 10 revised full papers presented together with 9 poster papers were carefully reviewed and selected from numerous submissions. The papers cover a wide range of topics in the field of biological data analysis and computational biology. They address important problems in biology, from the molecular and genomic dimension to the individual and population level, often drawing inspiration from biological systems in oder to produce solutions to biological problems.