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This book constitutes the refereed proceedings of the 11th International Conference on Artificial Immune Systems, ICARIS 2012, held in Taormia, Italy, in August 2012. The 19 revised selected papers presented were carefully reviewed and selected for inclusion in this book. In addition 4 papers of the workshop on bio and immune inspired algorithms and models for multi-level complex systems are included in this volume. Artificial immune systems (AIS) is a diverse and maturing area of research that bridges the disciplines of immunology, biology, medical science, computer science, physics, mathematics and engineering. The scope of AIS ranges from modelling and simulation of the immune system through to immune-inspired algorithms and in silico, in vitro and in vivo solutions.

This two volume set LNBI 10813 and LNBI 10814 constitutes the proceedings of the 6th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2018, held in Granada, Spain, in April 2018.The 88 regular papers presented were carefully reviewed and selected from 273 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases; bioinformatics tools to integrate omics dataset and address biological question; challenges and advances in measurement and self-parametrization of complex biological systems; computational genomics; computational proteomics; computational systems for modelling biological processes; drug delivery system design aided by mathematical modelling and experiments; generation, management and biological insights from big data; high-throughput bioinformatic tools for medical genomics; next generation sequencing and sequence analysis; interpretable models in biomedicine and bioinformatics; little-big data. Reducing the complexity and facing uncertainty of highly underdetermined phenotype prediction problems; biomedical engineering; biomedical image analysis; biomedical signal analysis; challenges in smart and wearable sensor design for mobile health; and healthcare and diseases.

This two-volume set LNBI 10813 and LNBI 10814 constitutes the proceedings of the 6th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2018, held in Granada, Spain, in April 2018.The 88 regular papers presented were carefully reviewed and selected from 273 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases; bioinformatics tools to integrate omics dataset and address biological question; challenges and advances in measurement and self-parametrization of complex biological systems; computational genomics; computational proteomics; computational systems for modelling biological processes; drug delivery system design aided by mathematical modelling and experiments; generation, management and biological insights from big data; high-throughput bioinformatic tools for medical genomics; next generation sequencing and sequence analysis; interpretable models in biomedicine and bioinformatics; little-big data. Reducing the complexity and facing uncertainty of highly underdetermined phenotype prediction problems; biomedical engineering; biomedical image analysis; biomedical signal analysis; challenges in smart and wearable sensor design for mobile health; and healthcare and diseases.

​This book constitutes the refereed proceedings of the 18th Conference of the Spanish Association for Artificial Intelligence, CAEPIA 2018, held in Granada, Spain, in October 2018.The 36 full papers presented were carefully selected from 240 submissions. The Conference of the Spanish Association of Artificial Intelligence (CAEPIA) is a biennial forum open to researchers from all over the world to present and discuss their latest scientific and technological advances in Antificial Intelligence (AI). Authors are kindly requested to submit unpublished original papers describing relevant research on AI issues from all points of view: formal, methodological, technical or applied.

This two volume set LNBI 10208 and LNBI 10209 constitutes the proceedings of the 5th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2017, held in Granada, Spain, in April 2017. The 122 papers presented were carefully reviewed and selected from 309 submissions. The scope of the conference spans the following areas: advances in computational intelligence for critical care; bioinformatics for healthcare and diseases; biomedical engineering; biomedical image analysis; biomedical signal analysis; biomedicine; challenges representing large-scale biological data; computational genomics; computational proteomics; computational systems for modeling biological processes; data driven biology - new tools, techniques and resources; eHealth; high-throughput bioinformatic tools for genomics; oncological big data and new mathematical tools; smart sensor and sensor-network architectures; time lapse experiments and multivariate biostatistics.

This two volume set LNBI 10208 and LNBI 10209 constitutes the proceedings of the 5th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2017, held in Granada, Spain, in April 2017. The 122 papers presented were carefully reviewed and selected from 309 submissions. The scope of the conference spans the following areas: advances in computational intelligence for critical care; bioinformatics for healthcare and diseases; biomedical engineering; biomedical image analysis; biomedical signal analysis; biomedicine; challenges representing large-scale biological data; computational genomics; computational proteomics; computational systems for modeling biological processes; data driven biology - new tools, techniques and resources; eHealth; high-throughput bioinformatic tools for genomics; oncological big data and new mathematical tools; smart sensor and sensor-network architectures; time lapse experiments and multivariate biostatistics.

This book constitutes the refereed proceedings of the 4th International Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2016, held in Granada, Spain, in April 2016. The 69 papers presented were carefully reviewed and selected from 286 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases; biomedical image analysis; biomedical signal analysis; computational systems for modeling biological processes; eHealth; tools for next generation sequencing data analysis; assistive technology for people with neuromotor disorders; fundamentals of biological dynamics and maximization of the information extraction from the experiments in the biological systems; high performance computing in bioinformatics, computational biology and computational chemistry; human behavior monitoring, analysis and understanding; pattern recognition and machine learning in the -omics sciences; and resources for bioinformatics.

The two volume set LNCS 9043 and 9044 constitutes the refereed proceedings of the Third International Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2015, held in Granada, Spain in April 2015. The 134 papers presented were carefully reviewed and selected from 268 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases, biomedical engineering, biomedical image analysis, biomedical signal analysis, computational genomics, computational proteomics, computational systems for modelling biological processes, eHealth, next generation sequencing and sequence analysis, quantitative and systems pharmacology, Hidden Markov Model (HMM) for biological sequence modeling, advances in computational intelligence for bioinformatics and biomedicine, tools for next generation sequencing data analysis, dynamics networks in system medicine, interdisciplinary puzzles of measurements in biological systems, biological networks, high performance computing in bioinformatics, computational biology and computational chemistry, advances in drug discovery and ambient intelligence for bio emotional computing.

The two volume set LNCS 9043 and 9044 constitutes the refereed proceedings of the Third International Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2015, held in Granada, Spain, in April 2015.The 135 papers presented were carefully reviewed and selected from 268 submissions. The scope of the conference spans the following areas: bioinformatics for healthcare and diseases, biomedical engineering, biomedical image analysis, biomedical signal analysis, computational genomics, computational proteomics, computational systems for modelling biological processes, e Health, next generation sequencing and sequence analysis, quantitative and systems pharmacology, Hidden Markov Model (HMM) for biological sequence modeling, advances in computational intelligence for bioinformatics and biomedicine, tools for next generation sequencing data analysis, dynamics networks in system medicine, interdisciplinary puzzles of measurements in biological systems, biological networks, high performance computing in bioinformatics, computational biology and computational chemistry, advances in drug discovery and ambient intelligence for bio emotional computing.

The two volume set LNCS 7491 and 7492 constitutes the refereed proceedings of the 12th International Conference on Parallel Problem Solving from Nature, PPSN 2012, held in Taormina, Sicily, Italy, in September 2012. The total of 105 revised full papers were carefully reviewed and selected from 226 submissions. The meeting began with 5 workshops which offered an ideal opportunity to explore specific topics in evolutionary computation, bio-inspired computing and metaheuristics. PPSN 2012 also included 8 tutorials. The papers are organized in topical sections on evolutionary computation; machine learning, classifier systems, image processing; experimental analysis, encoding, EDA, GP; multiobjective optimization; swarm intelligence, collective behavior, coevolution and robotics; memetic algorithms, hybridized techniques, meta and hyperheuristics; and applications.

The two volume set LNCS 7491 and 7492 constitutes the refereed proceedings of the 12th International Conference on Parallel Problem Solving from Nature, PPSN 2012, held in Taormina, Sicily, Italy, in September 2012. The total of 105 revised full papers were carefully reviewed and selected from 226 submissions. The meeting began with 6 workshops which offered an ideal opportunity to explore specific topics in evolutionary computation, bio-inspired computing and metaheuristics. PPSN 2012 also included 8 tutorials. The papers are organized in topical sections on evolutionary computation; machine learning, classifier systems, image processing; experimental analysis, encoding, EDA, GP; multiobjective optimization; swarm intelligence, collective behavior, coevolution and robotics; memetic algorithms, hybridized techniques, meta and hyperheuristics; and applications.

This book constitutes selected best papers from the 10th International Conference on Artificial Evolution, EA 2011, held in Angers, France, in October 2011. Initially, 33 full papers and 10 post papers were carefully reviewed and selected from 64 submissions. This book presents the 19 best papers selected from these contributions. The papers are organized in topical sections on ant colony optimization; multi-objective optimization; analysis; implementation and robotics; combinatorial optimization; learning and parameter tuning; new nature inspired models; probabilistic algorithms; theory and evolutionary search; and applications.

This Special Edited Volume is a unique approach towards Computational solution for the upcoming field of study called Vision Science. From a scientific firmament Optics, Ophthalmology, and Optical Science has surpassed an Odyssey of optimizing configurations of Optical systems, Surveillance Cameras and other Nano optical devices with the metaphor of Nano Science and Technology. Still these systems are falling short of its computational aspect to achieve the pinnacle of human vision system. In this edited volume much attention has been given to address the coupling issues Computational Science and Vision Studies. It is a comprehensive collection of research works addressing various related areas of Vision Science like Visual Perception and Visual system, Cognitive Psychology, Neuroscience, Psychophysics and Ophthalmology, linguistic relativity, color vision etc. This issue carries some latest developments in the form of research articles and presentations. The volume is rich of contents with technical tools for convenient experimentation in Vision Science. There are 18 research papers having significance in an array of application areas. The volume claims to be an effective compendium of computing developments like Frequent Pattern Mining, Genetic Algorithm, Gabor Filter, Support Vector Machine, Region Based Mask Filter, 4D stereo camera systems, Principal Component Analysis etc. The detailed analysis of the papers can immensely benefit to the researchers of this domain. It can be an Endeavour in the pursuit of adding value in the existing stock of knowledge in Vision Science.

This book describes hybrid intelligent systems using type-2 fuzzy logic and modular neural networks for pattern recognition applications. Hybrid intelligent systems combine several intelligent computing paradigms, including fuzzy logic, neural networks, and bio-inspired optimization algorithms, which can be used to produce powerful pattern recognition systems. Type-2 fuzzy logic is an extension of traditional type-1 fuzzy logic that enables managing higher levels of uncertainty in complex real world problems, which are of particular importance in the area of pattern recognition. The book is organized in three main parts, each containing a group of chapters built around a similar subject. The first part consists of chapters with the main theme of theory and design algorithms, which are basically chapters that propose new models and concepts, which are the basis for achieving intelligent pattern recognition. The second part contains chapters with the main theme of using type-2 fuzzy models and modular neural networks with the aim of designing intelligent systems for complex pattern recognition problems, including iris, ear, face and voice recognition. The third part contains chapters with the theme of evolutionary optimization of type-2 fuzzy systems and modular neural networks in the area of intelligent pattern recognition, which includes the application of genetic algorithms for obtaining optimal type-2 fuzzy integration systems and ideal neural network architectures for solving problems in this area.

This book constitutes the refereed proceedings of the 10th International Conference on Artificial Immune Systems, ICARIS 2011, held in Cambridge, UK, in July 2011. The 37 revised full papers were carefully reviewed and selected from numerous submissions. The papers are organized in topical sections on immunoinformatics and computational immunology; theory of immunological computation; and applied immunological computation.

Computer vision is the science and technology of making machines that see. It is concerned with the theory, design and implementation of algorithms that can automatically process visual data to recognize objects, track and recover their shape and spatial layout. The International Computer Vision Summer School - ICVSS was established in 2007 to provide both an objective and clear overview and an in-depth analysis of the state-of-the-art research in Computer Vision. The courses are delivered by world renowned experts in the field, from both academia and industry, and cover both theoretical and practical aspects of real Computer Vision problems. The school is organized every year by University of Cambridge (Computer Vision and Robotics Group) and University of Catania (Image Processing Lab). Different topics are covered each year. A summary of the past Computer Vision Summer Schools can be found at: http://www.dmi.unict.it/icvss This edited volume contains a selection of articles covering some of the talks and tutorials held during the first two editions of the school on topics such as Recognition, Registration and Reconstruction. The chapters provide an in-depth overview of these challenging areas with key references to the existing literature.

As cameras become more pervasive in our daily life, vast amounts of video data are generated. The popularity of YouTube and similar websites such as Tudou and Youku provides strong evidence for the increasing role of video in society. One of the main challenges confronting us in the era of information technology is to - fectively rely on the huge and rapidly growing video data accumulating in large multimedia archives. Innovative video processing and analysis techniques will play an increasingly important role in resolving the difficult task of video search and retrieval. A wide range of video-based applications have benefited from - vances in video search and mining including multimedia information mana- ment, human-computer interaction, security and surveillance, copyright prot- tion, and personal entertainment, to name a few. This book provides an overview of emerging new approaches to video search and mining based on promising methods being developed in the computer vision and image analysis community. Video search and mining is a rapidly evolving discipline whose aim is to capture interesting patterns in video data. It has become one of the core areas in the data mining research community. In comparison to other types of data mining (e. g. text), video mining is still in its infancy. Many challenging research problems are facing video mining researchers.

Bio-Inspired Hybrid Intelligent Systems for Image Analysis and Pattern Recognition comprises papers on diverse aspects of bio-inspired models, soft computing and hybrid intelligent systems. The articles are divided into four main parts. The first one consists of papers that propose new fuzzy and bio-inspired models to solve general problems. The second part deals with the main theme of modular neural networks in pattern recognition, which are basically papers using bio-inspired techniques. The third part contains papers that apply hybrid intelligent systems to the problem of time series analysis and prediction, while the fourth one shows papers dealing with bio-inspired models in optimization and robotics applications. An edited book in which both theoretical and application aspects are covered.

The College of Computing and Informatics (CCI) at UNC-Charlotte has three departments: Computer Science, Software and Information Systems, and Bioinformatics and Genomics. The Department of Computer Science offers study in a variety of specialized computing areas such as database design, knowledge systems, computer graphics, artificial intelligence, computer networks, game design, visualization, computer vision, and virtual reality. The Department of Software and Information Systems is primarily focused on the study of technologies and methodologies for information system architecture, design, implementation, integration, and management with particular emphasis on system security. The Department of Bioinformatics and Genomics focuses on the discovery, development and application of novel computational technologies to help solve important biological problems. This volume gives an overview of research done by CCI faculty in the area of Information & Intelligent Systems. Presented papers focus on recent advances in four major directions: Complex Systems, Knowledge Management, Knowledge Discovery, and Visualization. A major reason for producing this book was to demonstrate a new, important thrust in academic research where college-wide interdisciplinary efforts are brought to bear on large, general, and important problems. As shown in the research described here, these efforts need not be formally organized joint undertakings (through parts could be) but are rather a convergence of interests around grand themes.

This book constitutes the refereed proceedings of the 7th European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics, EvoBIO 2009, held in Tübingen, Germany, in April 2009 colocated with the Evo• 2009 events. The 17 revised full papers were carefully reviewed and selected from 44 submissions. EvoBio is the premiere European event for experts in computer science meeting with experts in bioinformatics and the biological sciences, all interested in the interface between evolutionary computation, machine learning, data mining, bioinformatics, and computational biology. Topics addressed by the papers include biomarker discovery, cell simulation and modeling, ecological modeling, uxomics, gene networks, biotechnology, metabolomics, microarray analysis, phylogenetics, protein interactions, proteomics, sequence analysis and alignment, as well as systems biology.

This book constitutes the thoroughly refereed post-conference proceedings of the 8th International Conference on Artificial Evolution, EA 2007, held in Tours, France in October 2007. The 27 revised full papers presented were carefully reviewed and selected from 62 submissions during two rounds of reviewing and improvement. The papers cover all aspects of artificial evolution: genetic programming, swarm intelligence, combinatorial and multi-objective optimization, theory in genetic algorithms and evolutionary systems, as well as applications of evolutionary algorithms.

This book constitutes the refereed proceedings of the 5th European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics, EvoBIO 2007, held in Valencia, Spain, April 2007. Coverage brings together experts in computer science with experts in bioinformatics and the biological sciences. It presents contributions on fundamental and theoretical issues along with papers dealing with different applications areas.

This two volume set constitutes the refereed proceedings of the 8th International Conference on Adaptive and Natural Computing Algorithms, ICANNGA 2007, held in Warsaw, Poland, in April 2007. Coverage in the first volume includes evolutionary computation, genetic algorithms, and particle swarm optimization. The second volume covers neural networks, support vector machines, biomedical signal and image processing, biometrics, computer vision.

This is volume I of the proceedings of the Second International Conference on Natural Computation, ICNC 2006. After a demanding review process 168 carefully revised full papers and 86 revised short papers were selected from 1915 submissions for presentation in two volumes. This first volume includes 130 papers related to artificial neural networks, natural neural systems and cognitive science, neural network applications, as well as evolutionary computation: theory and algorithms.

This book constitutes the thoroughly refereed post-proceedings of the 7th International Conference on Artificial Evolution, EA 2005, held in Lille, France, in October 2005. The 26 revised full papers presented were carefully reviewed and selected from 78 submissions. The papers cover all aspects of artificial evolution: genetic programming, machine learning, combinatorial optimization, co-evolution, self-assembling, artificial life and bioinformatics.

The field of bioinformatics has two main objectives: the creation and maintenance of biological databases, and the discovery of knowledge from life sciences data in order to unravel the mysteries of biological function, leading to new drugs and therapies for human disease. Life sciences data come in the form of biological sequences, structures, pathways, or literature. One major aspect of discovering biological knowledge is to search, predict, or model specific patterns of a given dataset, which have some relevance to an important biological phenomenon or another dataset. To date, many pattern recognition algorithms have been applied or catered to address a wide range of bioinformatics problems. The 2006 Workshop of Bioinformatics in Pattern Recognition (PRIB 2006) marks the beginning of a series of workshops that is aimed at gathering researchers applying pattern recognition algorithms in an attempt to resolve problems in computational biology and bioinformatics. This volume presentsthe proceedings of Workshop PRIB 2006 held in Hong Kong, China, on August 20, 2006. It includes 19 technical contributions that were selected by the Program Committee from 43 submissions. We give a brief introduction to pattern recognition in bioinformatics in the first paper. The rest of the volume consists of three parts. Part 1: signal and motif detection, and gene selection. Part 2: models of DNA, RNA, and protein structures. Part 3: biological databases and imaging.

This book presents the refereed joint proceedings of seven workshops on evolutionary computing, EvoWorkshops 2006, held in Budapest in April 2006. 65 revised full papers and 13 revised short papers presented were carefully reviewed and selected from a total of 149 submissions. The book is organized in topical sections including evolutionary bioinformatics, evolutionary computation in communications, networks, and connected systems, and more.

This is volume II of the proceedings of the Second International Conference on Natural Computation, ICNC 2006. After a demanding review process 168 carefully revised full papers and 86 revised short papers were selected from 1915 submissions for presentation in two volumes. The 124 papers in the second volume are organized in topical sections on additional topics in natural computation, natural computation techniques applications, hardware, and cross-disciplinary topics.

The International Workshop on Hybrid Metaheuristics reached its third edition with HM 2006. The active and successful participation in the past editions was a clear indication that the research community on metaheuristics and related areas felt the need for a forum to discuss speci?c aspects of hybridization of metaheuristics. The selection of papers for HM 2006 consolidated some of the mainstream issues that have emerged from the past editions. Firstly, there are prominent examples of e?ective hybrid techniques whose design and implementation were motivated by challenging real-world applications. We believe this is particularly important for two reasons: on the one hand, researchers are conscious that the primary goal of developing algorithms is to solve relevant real-life problems; on the other hand, the path towarde?cient solving methods for practical problems is a source of new outstanding ideas and theories. A second important issue is that the research community on metaheur- tics has become increasingly interested in and open to techniques and methods known from arti?cial intelligence (AI) and operations research (OR). So far, the most representative examples of such integration have been the use of AI/OR techniques as subordinates of metaheuristic methods. As a historical and - ymological note, this is in perfect accordance with the original meaning of a metaheuristic as a “general strategy controlling a subordinate heuristic. ” The awareness of the need for a sound experimental methodology is a third keypoint.

The three volume set LNCS 3610, LNCS 3611, and LNCS 3612 constitutes the refereed proceedings of the First International Conference on Natural Computation, ICNC 2005, held in Changsha, China, in August 2005 as a joint event with the Second International Conference on Fuzzy Systems and Knowledge Discovery FSKD 2005 (LNAI volumes 3613 and 3614). The program committee selected 313 carefully revised full papers and 189 short papers for presentation in three volumes from 1887 submissions. The first volume includes all the contributions related to learning algorithms and architectures in neural networks, neurodynamics, statistical neural network models and support vector machines, and other topics in neural network models; cognitive science, neuroscience informatics, bioinformatics, and bio-medical engineering, and neural network applications such as communications and computer networks, expert system and informatics, and financial engineering. The second volume concentrates on neural network applications as pattern recognition and diagnostics, robotics and intelligent control, signal processing and multi-media, and other neural network applications; evolutionary learning, artificial immune systems, evolutionary theory, membrane, molecular, DNA computing, and ant colony systems. The third volume deals with evolutionary methodology, quantum computing, swarm intelligence and intelligent agents; natural computation applications as bioinformatics and bio-medical engineering, robotics and intelligent control, and other applications of natural computation; hardware implementations of natural computation, and fuzzy neural systems as well as soft computing.

In this volume we present the contributions for the 18th European Conference on Genetic Programming (EuroGP 2005). The conference took place from 30 March to 1 April in Lausanne, Switzerland. EuroGP is a well-established conf- ence and the only one exclusively devoted to genetic programming. All previous proceedings were published by Springer in the LNCS series. From the outset, EuroGP has been co-located with the EvoWorkshops focusing on applications of evolutionary computation. Since 2004, EvoCOP, the conference on evolutionary combinatorial optimization, has also been co-located with EuroGP, making this year's combined events one of the largest dedicated to evolutionary computation in Europe. Genetic programming (GP) is evolutionary computation that solves complex problems or tasks by evolving and adapting a population of computer programs, using Darwinian evolution and Mendelian genetics as its sources of inspiration. Some of the 34 papers included in these proceedings address foundational and theoretical issues and there is also a wide variety of papers dealing with di?erent application areas, such as computer science, engineering, language processing, biology and computational design, demonstrating that GP is a powerful and practical problem-solving paradigm.