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Abstract: The home healthcare of fragile or elderly people may be facilitated by IC technologies in order to monitor continuously the health level and to assist professionals, physicians and social workers. The assessment of the level of autonomy is one of the main indicators for adapting the level of care. The standardized tools (AGGIR or ADL) evaluate the capacities to perform autonomously the daily activities. These are user dependant. This paper presents scientific works on acquisition and interpretation of the signals derived from accelerometers in a Micro system, called “actimometer”. It can be embedded in the underwear to monitor continuously the level of activity, the capacities to displacements and transfers. The interpretation is so accurate to classify between different kinds of transfers in an ecological scenario. Results show that accelerometers data reproducibility depend on the two criteria: velocity and subject. In addition, a new method is able to differentiate BtS (Back-to-Sit) and StS (Sit-to-Stand) at the three velocities with a overall sensitivity and specificity equal to 95.32 and 96.10% respectively. Finally, the transition duration is determined for all trials. [Copyright &y& Elsevier]