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Following the fast spread of Covid-19 across Europe and North America in March 2020, many people started stockpiling commodities like toilet paper. Despite the high relevance for public authorities to adequately address stockpiling behavior, empirical studies on the psychological underpinnings of toilet paper stockpiling are still scarce. In this study, we investigated the relation between personality traits, perceived threat of Covid-19, and stockpiling of toilet paper in an online survey (N = 996) across 22 countries. Results suggest that people who felt more threatened by Covid-19 stockpiled more toilet paper. Further, a predisposition towards Emotionality predicted the perceived threat of Covid-19 and affected stockpiling behavior indirectly. Finally, Conscientiousness was related to toilet paper stockpiling, such that individuals higher in Conscientiousness tended to stockpile more toilet paper. These results emphasize the importance of clear communication by public authorities acknowledging anxiety and, at the same time, transmitting a sense of control. [ABSTRACT FROM AUTHOR]

Biliary atresia, a fibro-obliterative disease of the newborn, is usually initially treated by Kasai portoenterostomy, although there are many variations in technique and different options for post-operative adjuvant medical therapy. A questionnaire on such topics (e.g., open vs. laparoscopic; the need for liver mobilisation; use of post-operative steroids; use of post-operative anti-viral therapy, etc.) was circulated to delegates (n = 43) of an international webinar (Biliary Atresia and Related Diseases—BARD) held in June 2021. Respondents were mostly European, but included some from North America, and represented 18 different countries overall. The results of this survey are presented here, together with a commentary and review from an expert panel convened for the meeting on current trends in practice. [ABSTRACT FROM AUTHOR]

In this work, we developed a systematic map to identify and catalogue the literature pertaining to disease modelling for agricultural crops worldwide. Searches were performed in 2021 in the Web of Science and Scopus for papers reporting any type of disease model for 103 crops. In total, 768 papers were retrieved, and their descriptive metadata were extracted. The number of papers found increased from the mid-1900s to 2020, and most of the studies were from North America and Europe. More disease models were retrieved for wheat, potatoes, grapes, and apples than for other crops; the number of papers was more affected by the crop's economic value than by its cultivated area. The systematic map revealed an underrepresentation of disease models for maize and rice, which is not justified by either the crop economic value or by disease impact. Most of the models were developed to understand the pathosystem, and fewer were developed for tactical disease management, strategic planning, or scenario analysis. The systematic map highlights a variety of knowledge gaps and suggests questions that warrant further research. [ABSTRACT FROM AUTHOR]

"Go to temples of science and ideas of Europe. Imitate the Tugendbund, 'the Union of Virtue', of which thousands of German youth are the members. Always keep the rule of 'Fit soul is in fit body' in mind" (Petrov, 2013, p. 72). This study aimed to show the similarities, in terms of expression, emphasis, and implication, in the about/mission/vision/goals/objectives of various science centers from around the world and in the basic themes derived from Snellman's statement above, namely, Science for all, Science Centers for all, and Human welfare that he made as a challenge to not only his people but to everyone. Document and content analyses were applied in the study. Within the scope of these analyses, this study investigated the about/mission/vision/goals/objectives sections of websites of science centers from around the world (Asia, Europe, Global, Latin America/The Caribbean, North America, Africa). From this investigation, similar basic themes, derived from Snellman's statement challenging his people/everyone to adopt this devotion to science, were found in the areas of i) expression in ASTC, CIMUSET/CSTM, CASC and SAASTEC; ii) emphasis in ECSITE, ASDC, ASCN and NSCF; and iii) implication in ASPAC, ASTEN, NCSM, ABCMC and Red-POP. These basic themes, as found in the about/mission/vision/goals/objectives of science centers, can, in effect, be narrowed down to the one theme of "cultural institutions will be a big part of human life" (Madsen 2017, p. 68) science centers in the global village (Touraine, 2016, p. 121) of the future.

University scientific research ability is an important indicator to express the strength of universities. In this paper, the evaluation of university scientific research ability is investigated based on the output of sci-tech papers. Four university alliances from North America, UK, Australia, and China, are selected as the case study of the university scientific research evaluation. Data coming from Thomson Reuters InCites are collected to support the evaluation. The work has contributed new framework to the issue of university scientific research ability evaluation. At first, we have established a hierarchical structure to show the factors that impact the evaluation of university scientific research ability. Then, a new MCDM method called D-AHP model is used to implement the evaluation and ranking of different university alliances, in which a data-driven approach is proposed to automatically generate the D numbers preference relations. Next, a sensitivity analysis has been given to show the impact of weights of factors and sub-factors on the evaluation result. At last, the results obtained by using different methods are compared and discussed to verify the effectiveness and reasonability of this study, and some suggestions are given to promote China’s scientific research ability. [ABSTRACT FROM AUTHOR]

The global biodiversity crisis and constantly growing human impact on the natural environment call for more evidence where conservation actions are the most urgent. As the agricultural lands are under increased pressure of growing human food needs here the literature survey on farmland bird conservation (FBC) was conducted to reveal geographical distribution in research intensity, the topics addressed and to identify potential drivers for the worldwide scientific effort. The Scopus database search has revealed 2290 papers dedicated to FBC from the period 1990-2020. The distribution was spatially uneven with most papers published in Western Europe and North America. Scientific collaboration was also spatially biased in favor of countries located close to each other and having high scientific capacity. The analysis also revealed 139 terms representing main topics raised in FBC research. The number of FBC papers per country was positively correlated with Gross Domestic Production (GDP), the total number of scientific papers, and number of threatened species, and negatively with the GDP from agricultural production, whereas it was not related to area of agricultural lands or bird species richness. Spatial and thematic biases in studies of farmland birds may have important consequences since uneven scientific evidence constrains development of proper conservation solutions and limits their implementation. We conclude that research on FBC should be globally coordinated and flexible enough to undertake burning conservation problems adjusted to regional differences in agriculture, socio-economy, and bird diversity. [ABSTRACT FROM AUTHOR]

Background: The objective of this systematic review is to determine the extent and quality of evidence for use of different types of locking fluids to prevent central venous access device complications in adult critical care patients. Specifically, rates of catheter-related bloodstream infection, colonization, and occlusion were considered. All types of devices were included in the review: central venous catheters, peripherally- inserted central catheters and hemodialysis catheters. Methods: Eligibility criteria. Papers had to include adult (>18 years old) critical care patients, be experimental trials, conducted in North America and Europe, and published in peer-reviewed journals from 2010 onwards. Information sources. A search of Medline and EMBASE databases was performed. The search is current as of November 28th, 2022. Risk of bias. The Cochrane Risk of Bias 2 and the Risk of Bias In Non-Randomized Studies of Intervention tools were used to assess the risk of bias in included studies. Results: Included studies. A total of 240 paper titles and abstracts underwent review, of these seven studies met the final criteria for quality appraisal. A total of three studies earned a low risk of bias quality appraisal. Discussion: Limitations of evidence. Due to heterogeneity of types of locking fluids investigated and small number of studies identified, meta-analysis of results was not possible. Interpretation. Out of all fluids investigated, only citrate 46.7% was found to statistically reduce central venous access device complication rates. This systematic review has also identified a gap in the literature regarding studies of locking fluids that are adequately powered in this patient population. Future directions: Future research should include investigations and use of novel locking fluids with more effective properties against complications. It is imperative that future studies are adequately powered, randomized controlled trials in this patient population to facilitate optimal evidence-based care. [ABSTRACT FROM AUTHOR]

Featured Application: This work helps to realise improvements in the cultivation of corn and corn–nixtamalisation–dough–tortillas production, which could mean more environmentally friendly food production. The research on the environmental impacts of corn-derived products has been mainly on cultivation techniques and the production of biofuels, so there is limited information on the impacts produced by the transformation of corn for human consumption. The tortilla is a millennial product derived from corn of which consumption is increasing in North America. The aim of this study is to identify the environmental hotspots of the tortilla using a life cycle assessment (LCA) approach. The process studied included only the corn–nixtamalisation–dough–tortillas production. The functional unit is one kg of tortillas packed in kraft paper. The impacts of the tortilla production process were evaluated using SimaPro 8.5.0 software, considering ReCiPe Midpoint. The production has the greatest impact in 15 of the 18 impact categories. The normalisation reveals that the most significant impacts concentrate in the categories terrestrial acidification (TA), particulate matter formation (PMF), marine ecotoxicity (MET) and fossil fuel depletion (FD). Improvements in the cultivation could mean more environmentally friendly tortilla production. [ABSTRACT FROM AUTHOR]

Objective: To practice evidence-based medicine, clinicians must be competent in information literacy (IL). Few studies acknowledge the critical role that reading strategies play in IL instruction and assessment of health professional students. The purpose of this study was to understand the information-seeking and evaluation behaviors of doctor of veterinary medicine (DVM) students in regard to scientific papers. Methods: The authors studied DVM student behaviors across eight programs in North America using a web-based survey of closed- and open-ended questions about finding and evaluating scientific papers, including a task to read a linked scientific paper and answer questions about it. Results: A total of 226 individuals responded to the survey. The sections of a scientific paper that were most commonly read were the abstract, introduction, and conclusions. Students who reported reading a higher proportion of scientific papers were more likely to feel confident in their abilities to interpret them. A third of respondents answered open-ended questions after the paper reading task. Respondents felt the least amount of confidence with one of the final steps of evidence-based medicine, that of interpreting the significance of the paper to apply it in veterinary medicine. Conclusions: DVM students may lack the skills needed to evaluate scientific literature and need more practice and feedback in evaluating and interpreting scientific papers. Librarians who support DVM students can (1) help DVM students to efficiently evaluate scientific literature, (2) seek training opportunities in alternative modes of teaching and learning IL skills, and (3) partner with veterinary faculty and clinicians to provide students with practice and feedback in information evaluation. [ABSTRACT FROM AUTHOR]

Globalization has created a need for culturally aware globally minded students across North America. Study abroad has increasingly become a normalized part of a young person's education however financial and temporal commitments attached to longer study abroad experiences hinder participation for many. In response, the field school model, which generally involves shorter stays and less financial commitment, has increased in popularity. The field school is a particular model of study abroad that shares characteristics with short-term study abroad, fieldwork, service learning and other models but requires definition. The purpose of this paper is to define the field school model of study abroad within the contest of study to assist administrators when presented the option, faculty when determining experiential learning opportunities and students in determining their educational path. The paper provides a working definition and nine defining features of the field school that distinguish it from other study abroad models. [ABSTRACT FROM AUTHOR]

Background: Frameworks used in research impact evaluation studies vary widely and it remains unclear which methods are most appropriate for evaluating research impact in the field of surgical research. Therefore, we aimed to identify and review the methods used to assess the impact of surgical intervention trials on healthcare and to identify determinants for surgical impact. Methods: We searched journal databases up to March 10, 2020 for papers assessing the impact of surgical effectiveness trials on healthcare. Two researchers independently screened the papers for eligibility and performed a Risk of Bias assessment. Characteristics of both impact papers and trial papers were summarized. Univariate analyses were performed to identify determinants for finding research impact, which was defined as a change in healthcare practice. Results: Sixty-one impact assessments were performed in 37 included impact papers. Some surgical trial papers were evaluated in more than one impact paper, which provides a total of 38 evaluated trial papers. Most impact papers were published after 2010 (n = 29). Medical records (n = 10), administrative databases (n = 22), and physician's opinion through surveys (n = 5) were used for data collection. Those data were analyzed purely descriptively (n = 3), comparing data before and after publication (n = 29), or through time series analyses (n = 5). Significant healthcare impact was observed 49 times and more often in more recent publications. Having impact was positively associated with using medical records or administrative databases (ref.: surveys), a longer timeframe for impact evaluation and more months between the publication of the trial paper and the impact paper, data collection in North America (ref.: Europe), no economic evaluation of the intervention, finding no significant difference in surgical outcomes, and suggesting de-implementation in the original trial paper. Conclusions and implications: Research impact evaluation receives growing interest, but still a small number of impact papers per year was identified. The analysis showed that characteristics of both surgical trial papers and impact papers were associated with finding research impact. We advise to collect data from either medical records or administrative databases, with an evaluation time frame of at least 4 years since trial publication. [ABSTRACT FROM AUTHOR]

Background: Transcranial magnetic stimulation (TMS), as a non-invasive neuromodulation technique, has been widely used in the treatment of Parkinson's disease (PD). The increasing application of TMS has promoted an increasing number of clinical studies. In this paper, a bibliometric analysis of existing studies was conducted to reveal current research hotspots and guide future research directions. Method: Relevant articles and reviews were obtained from the Science Citation Index Expanded of Web of Science Core Collection database. Data related to publications, countries, institutions, authors, journals, citations, and keywords in the studies included in the review were systematically analyzed using VOSviewer 1.6.18 and Citespace 6.2.4 software. Result: A total of 1,894 papers on the topic of TMS in PD between 1991 and 2022 were analyzed and visualized to identify research hotspots and trends in the field. The number of annual publications in this field of study has increased gradually over the past 30 years, with the number of annual publications peaking in 2022 (n = 150). In terms of publications and total citations, countries, institutions, and authors from North America and Western Europe were found to make significant contributions to the field. The current hotspot focuses on the effectiveness of TMS for PD in different stimulation modes or different stimulated brain regions. The keyword analysis indicates that the latest research is oriented to the mechanism study of TMS for motor symptoms in PD, and the non-motor symptoms are also receiving more attention. Conclusion: Our study offers insights into the current hotspots and emerging trends of TMS in the rehabilitation of PD. These findings may serve as a guide for future research and the application of TMS for PD. [ABSTRACT FROM AUTHOR]

Background: The German naturalist Alexander von Humboldt conducted an expedition through the American continent, alongside Aimé Bonpland, from 1799 to 1804. Before finally returning to Europe, they decided to take a side trip to the USA between May 20 and July 7, 1804. Humboldt's most detailed account of his time in the USA consists of a manuscript entitled "Plantae des États-Unis" (1804), containing information on useful plants and timber of the country. The aim of this paper is to retrieve, for the first time, ethnobotanical information regarding North American plants and their uses inside this Humboldt's manuscript as well as to highlight the erasure and invisibilization of North American Indigenous knowledge within historical documents and bibliography, mainly during the nineteenth century. Methods: "Plantae des États-Unis" (digitized version and its transcription) was carefully analyzed, and information on plant species mentioned in the manuscript (including botanical and vernacular names, traditional uses, and general observations) was retrieved. Traditional uses were correlated with ethnobotanical data from the Native American Ethnobotany Database and encyclopedic literature on North American plants from the nineteenth and early twentieth centuries, as well as recent pharmacological studies searched in scientific papers. Results: In the manuscript are mentioned 28 species distributed in 15 botanical families, with Fagaceae (9 Quercus species) being the most representative. All species are USA natives, except for one undetermined species (only the genus was mentioned, Corylus). Four species were directly mentioned as medicinal (Toxicodendron radicans, Liriodendron tulipifera, Actaea racemosa, and Gillenia stipulata), while other four were described as tanning agents (astringent) (Cornus florida, Diospyros virginiana, Quercus rubra, and Quercus velutina). Two species were described as bitter (Xanthorhiza simplicissima and A. racemosa). Nine Quercus species were described, but five were reported as the most useful oaks for cultivation in Europe (Quercus bicolor, Quercus castanea, Quercus virginiana, Quercus michauxii, and Quercus alba); three of them were used for ship construction (Q. virginiana, Q. michauxii, and Q. alba), two as astringent (Q. rubra and Q. stellata), and one had wood of poor quality (Quercus phellos). One species was described as a yellow dye (Hydrastis canadensis), and the other was mentioned as toxic (Aesculus pavia). Ten species did not have any useful applications listed. Conclusions: Although "Plantae des États-Unis" is a brief collection of annotations, these data reveal a historical scenario of outstanding plants with social and economic interest in the USA at the beginning of the nineteenth century. The data highlight a clear process of suppression of the traditional knowledge of Native North American Indigenous peoples in past historical records and literature, due to the lack of acknowledgment by white European settlers and American-born explorers. This ethnobotanical inventory may help us understand the relationship between plants and Native North American Indigenous peoples, as well as European naturalists and settlers, and USA-born people in the past, and reflect on the importance of Indigenous traditional knowledge, bioeconomy, sustainable management, and conservation of biodiversity in the present and future. [ABSTRACT FROM AUTHOR]

Space efficiency in North American skyscrapers is crucial due to financial, societal, and ecological reasons. High land prices in major cities require maximizing every square foot for financial viability. Skyscrapers must accommodate growing populations within limited spaces, reducing urban sprawl and its associated issues. Efficient designs also support environmental sustainability and enhance city aesthetics, while optimizing infrastructure and services. However, no comprehensive study has examined the key architectural and structural features impacting the space efficiency of these towers in North America. This paper fills this gap by analyzing data from 31 case study skyscrapers. Findings indicated that (1) central core was frequently employed in the organization of service core; (2) most common forms were setback, prismatic, and tapered configurations; (3) outriggered frame and shear walled frame systems were mostly used; (4) concrete was the material in most cases; and (5) average space efficiency was 76%, and the percentage of core area to gross floor area (GFA) averaged 21%, from the lowest of 62% and 13% to the highest of 84% and 31%. It is expected that this paper will aid architectural and structural designers, and builders involved in shaping skyscrapers in North America. [ABSTRACT FROM AUTHOR]

We examine the financial performance of the forest products industry in the initial phase of the COVID-19 pandemic, employing data for publicly trading companies in the industry globally. We first examine the market investor reaction to the declaration of a pandemic by the World Health Organization (WHO) in March 2020 by conducting an event-study analysis. Then, we analyze medium-term changes in stock returns and their systematic risk by an econometric estimation of the capital asset pricing model. Our event-study analysis of the forest products industry shows that the forestry subsector was impacted more than the paper subsector when the WHO declared the pandemic. The effect was most prominent in North America. We find that the systematic risk for the forestry subsector tended to increase during 2020, until October. Again, this effect was most clear in North America. Conversely, the impact on the paper subsector was more stable. [ABSTRACT FROM AUTHOR]

Citizen science (CS) currently refers to the participation of non-scientist volunteers in any discipline of conventional scientific research. Over the last two decades, nature-based CS has flourished due to innovative technology, novel devices, and widespread digital platforms used to collect and classify species occurrence data. For scientists, CS offers a low-cost approach of collecting species occurrence information at large spatial scales that otherwise would be prohibitively expensive. We examined the trends and gaps linked to the use of CS as a source of data for species distribution models (SDMs), in order to propose guidelines and highlight solutions. We conducted a quantitative literature review of 207 peer-reviewed articles to measure how the representation of different taxa, regions, and data types have changed in SDM publications since the 2010s. Our review shows that the number of papers using CS for SDMs has increased at approximately double the rate of the overall number of SDM papers. However, disparities in taxonomic and geographic coverage remain in studies using CS. Western Europe and North America were the regions with the most coverage (73%). Papers on birds (49%) and mammals (19.3%) outnumbered other taxa. Among invertebrates, flying insects including Lepidoptera, Odonata and Hymenoptera received the most attention. Discrepancies between research interest and availability of data were as especially important for amphibians, reptiles and fishes. Compared to studies on animal taxa, papers on plants using CS data remain rare. Although the aims and scope of papers are diverse, species conservation remained the central theme of SDM using CS data. We present examples of the use of CS and highlight recommendations to motivate further research, such as combining multiple data sources and promoting local and traditional knowledge. We hope our findings will strengthen citizen-researchers partnerships to better inform SDMs, especially for less-studied taxa and regions. Researchers stand to benefit from the large quantity of data available from CS sources to improve global predictions of species distributions. [ABSTRACT FROM AUTHOR]

Introduction: Degenerative Cervical Myelopathy (DCM) is a common and disabling condition, with a relatively modest research capacity. In order to accelerate knowledge discovery, the AO Spine RECODE-DCM project has recently established the top priorities for DCM research. Uptake of these priorities within the research community will require their effective dissemination, which can be supported by identifying key opinion leaders (KOLs). In this paper, we aim to identify KOLs using artificial intelligence. We produce and explore a DCM co-authorship network, to characterise researchers' impact within the research field. Methods: Through a bibliometric analysis of 1674 scientific papers in the DCM field, a co-authorship network was created. For each author, statistics about their connections to the co-authorship network (and so the nature of their collaboration) were generated. Using these connectedness statistics, a neural network was used to predict H-Index for each author (as a proxy for research impact). The neural network was retrospectively validated on an unseen author set. Results: DCM research is regionally clustered, with strong collaboration across some international borders (e.g., North America) but not others (e.g., Western Europe). In retrospective validation, the neural network achieves a correlation coefficient of 0.86 (p<0.0001) between the true and predicted H-Index of each author. Thus, author impact can be accurately predicted using only the nature of an author's collaborations. Discussion: Analysis of the neural network shows that the nature of collaboration strongly impacts an author's research visibility, and therefore suitability as a KOL. This also suggests greater collaboration within the DCM field could help to improve both individual research visibility and global synergy. [ABSTRACT FROM AUTHOR]

Introduction: Local tissue destruction following envenomation from North American snakes, particularly those within the Crotalinae subfamily, has the potential to progress to compartment syndrome. The pathophysiology of venom-induced compartment syndrome (VICS) is a debated topic and is distinct from trauma/reperfusion-induced compartment syndrome. Heterogeneity exists in the treatment practices of VICS, particularly regarding the decision to progress to fasciotomy. Associations with functional outcomes and evolution in clinical practice since the introduction of Crotalidae polyvalent immune Fab (FabAV) have not been well defined. Our goal was to identify the potential gaps in the literature regarding this phenomenon, as well as illuminate salient themes in the clinical characteristics and treatment practices of VICS. Methods: We conducted this systematic scoping-style review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Records were included if they contained data surrounding the envenomation and hospital course of one or more patients who were envenomated by a snake species native to North America and were diagnosed with compartment syndrome from 1980-2020. Results: We included 19 papers: 10 single- or two-patient case reports encompassing 12 patients, and nine chart reviews providing summary statistics of the included patients. In case reports, the median compartment pressure when reported was 60 millimeters of mercury (interquartile range 55-68), 66% underwent fasciotomy, and functional outcomes varied. Use of antivenom appeared to be more liberal with FabAV than the earlier antivenin Crotalidae polyvalent. Rapid progression of swelling was the most commonly reported symptom. Among the included retrospective chart reviews, important data such as compartment pressures, consistent laboratory values, and snake species was inconsistently reported. Conclusions: Venom-induced compartment syndrome is relatively rare. Existing papers generally describe good outcomes even in the absence of surgical management. Significant gaps in the literature regarding antivenom dosing practices, serial compartment pressure measurements, and functional outcomes highlight the need for prospective studies and consistent standardized reporting. [ABSTRACT FROM AUTHOR]

Although unidentified flying objects (UFOs) have long held the public's attention, most research has been conducted by federal agencies who have typically restricted access to such research by classifying or denying the research altogether.1 As a result, countless researchers have taken it upon themselves to investigate the phenomenon over the decades with some of this research making its way into publicly accessible archives. This study provides a history of UFO-related research and archival collections, through an examination of trends gleaned via an inventory of publicly accessible physical collections. The study found that within North America there are sixty-two unique, non-federal collections spread across universities, museums, public libraries, and historical societies. Twenty-two of these collections exclusively contain UFO research content. Collections were created by those who thought UFOs were misidentified objects (the original federal conclusion) and those who believed that there was more to the phenomenon. UFO archival collections started to catch on in the 1970s and are amongst the most popular at their institutions today. [ABSTRACT FROM AUTHOR]

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This paper presents extensive verification, sensitivity, and application studies for an online substation grounding grid condition monitoring method proposed in a companion paper. The studies are conducted using a realistic substation grounding grid and associated feeder configurations commonly encountered in North America. The verification studies confirm that the proposed method is able to estimate the substation grounding impedances with acceptable accuracy. Main factors impacting measurement accuracy are identified and quantified through sensitivity studies. The findings lead to a guide for the implementation and operation of the proposed method. An application case is presented to demonstrate how the gradual deterioration of substation grounding grid can be monitored using the proposed method. [ABSTRACT FROM AUTHOR]

Exotic insect species are an increasing concern with international trade. Detecting and removing any insect are thus important for any imported/exported product, including wood products. For example, wood transportation is known to be an important pathway for the introduction and dispersal of the Emerald Ash Borer, Agrilus planipennis (Coleoptera: Buprestidae). This Asian species is causing high mortality of ash trees in its introduced range because of the weak natural defense of trees and the virtual absence of natural enemies. For similar reasons, there are concerns in Europe that the Bronze Birch Borer, A. anxius, native to North America, could be introduced and cause important birch mortality. Having efficient detection methods and phytosanitary measures to prevent introducing it is thus important. In this study, we evaluated tomodensitometry—or CT-scan—as a detection method for detecting these two Agrilus spp. using debarking as the method of reference. Using CT-scan, we were also able to precisely measure the depth of insects in ash and birch trees in order to recommend proper phytosanitary measures for exportation and importation of wood products. Both techniques efficiently detect the presence of insects in ash, paper birch, and yellow birch. However, the number of A. anxius detected depended on both the technique and the diameter of the sample. The depth of insects depended on tree species, sample diameter, and life-stage. Globally, A. planipennis are deeper in ash trees than A. anxius in birch trees, and prepupae are deeper than larvae. The maximal depth in the sapwood (excluding bark thickness) for ash, paper birch, and yellow birch was 21.9 mm, 6.30 mm, and 3.22 mm, respectively. While CT-scan is more expensive and requires access to expensive equipment, debarking is more time-consuming, especially if the number of insects needs to be determined. [ABSTRACT FROM AUTHOR]

Developing appropriate signal timing strategies is a primary concern in traffic signal control; however, professionals are constrained by predefined controller options. Existing signal controllers in North America adhere to National Electrical Manufacturers Association (NEMA) standards with ring-barrier control (RBC) design. Due to unique traffic conditions and objectives for each traffic mode, conflicts arise, making it challenging to devise suitable traffic control strategies within current controllers. The limitations include inflexibility in defining pretimed signal diagrams, modifying them, and defining algorithms for modification. This paper introduces the event-based controller (EBC) framework, implemented in DUMKA_E software, capable of replicating NEMA-based RBC functionalities while providing additional flexibility beyond conventional RBC controllers. The EBC eliminates the asymmetry of flexibilities in existing traffic controller frameworks, addressing the challenges mentioned. Overcoming critical limitations of RBC, such as barrier constraints and restricted functionalities to built-in algorithms, the EBC empowers professionals to craft custom traffic signal control strategies. Unlike approaches enhancing RBC with complex computation, the EBC offers flexible functionalities without sacrificing simplicity. The study shows that the EBC's fundamental concepts are no more intricate than RBC's, positioning the EBC as a potential traffic controller framework. The paper establishes the EBC's capability to reproduce RBC controllers' core logic, showcasing advanced abilities for more efficient control logic than RBC. The EBC's functionalities enable context-sensitive traffic signal control strategies, catering to special conditions like multi-modal activities and diverse priority requests, highlighting its full potential. [ABSTRACT FROM AUTHOR]

Precipitable water vapor (PWV) is one of the most critical data in many meteorological departments. This component has great spatial and temporal changes, so the global positioning system (GPS) always seeks to increase the accuracy of estimating the water vapor component in the troposphere. The waves sent by the satellites of this system are delayed due to passing through atmospheric layers such as the troposphere. In this paper, interpolation methods are used to estimate precipitable water vapor. Inverse multiquadric (IMQ) interpolation which is based on radial basis functions, artificial neural network (ANN) method, and inverse distance weighted (IDW) which are the most common method of interpolation in meteorology. A region in North America with 23 GPS stations was randomly selected. Then, the interpolation of precipitable water vapor on a summer day is done using GPS data. The root mean square error value (RMSE) for the IMQ method was the lowest compared to other methods and was equal to 2.11 mm. Finally, using the IMQ interpolation method, a dense map of Precipitable water vapor changes in the troposphere layer is developed for the study area. [ABSTRACT FROM AUTHOR]

Rocky Mountain spotted fever (RMSF) is a fatal tick-borne zoonotic disease that has emerged as an epidemic in western North America since the turn of the 21st century. Along the US south-western border and across northern Mexico, the brown dog tick, Rhipicephalus sanguineus, is responsible for spreading the disease between dogs and humans. The widespread nature of the disease and the ongoing epidemics contrast with historically sporadic patterns of the disease. Because dogs are amplifying hosts for the Rickettsia rickettsii bacteria, transmission dynamics between dogs and ticks are critical for understanding the epidemic. In this paper, we developed a compartment metapopulation model and used it to explore the dynamics and drivers of RMSF in dogs and brown dog ticks in a theoretical region in western North America. We discovered that there is an extended lagdas much as two yearsdbetween introduction of the pathogen to a naïve population and epidemic-level transmission, suggesting that infected ticks could disseminate extensively before disease is detected. A single large city-size population of dogs was sufficient to maintain the disease over a decade and serve as a source for disease in surrounding smaller towns. This model is a novel tool that can be used to identify high risk areas and key intervention points for epidemic RMSF spread by brown dog ticks. [ABSTRACT FROM AUTHOR]

Societal Impact Statement: Over the last 50 years, the practice of 'intercropping' (planting a mixture of several crops on the same field) has drawn growing attention in crop science. Given its high yields but low requirement for fertiliser or pesticides, it offers considerable advantages over conventional 'industrial' agriculture. Nevertheless, although research on intercropping has been conducted since the late 19th century, that work became largely invisible after 1945 as the rapid rise of industrial agriculture erased alternative approaches from view. Since the 1970s, however, intercropping and other alternatives have reappeared on the research agenda as the damaging impacts of industrial agriculture have become evident. Summary: Intercropping has long been of interest in agro‐ecology. Indeed, as the first generation of (English‐speaking) agro‐ecologists saw it, research on intercropping began in the 1970s and 1980s just as the field was beginning to emerge. Although the evidence confirms a rapid increase in such work from the 1970s, however, what nearly all agro‐ecologists then overlooked was the existence of two older traditions of work dating from the late 19th century. The aim of this paper is to explain why early agro‐ecologists were unaware of previous work. The history of research on intercropping in both the English‐ and German‐speaking worlds was traced using the journal literature as well as textbooks of agronomy. What this survey revealed is that in Europe and North America, agronomists had been working on intercropping since the 1890s, and during the interwar period and into the 1950s, the practice attracted considerable attention from colonial agronomists. Although this early work was in the public domain during the 1970s, however, few agro‐ecologists noticed it. There are various reasons why the first generation of agro‐ecologists might have known about but chose to ignore earlier work on intercropping. But more likely is that most members of that generation were simply unaware of the older work. For the forgotten history of intercropping, research appears to be just one aspect of a more general phenomenon during the 20th century in which a wide variety of 'alternative' cultivation practices were marginalised after 1945, only to re‐emerge from the 1970s as the social and environmental consequences of industrial agriculture came under attack. Over the last 50 years, the practice of 'intercropping' (planting a mixture of several crops on the same field) has drawn growing attention in crop science. Given its high yields but low requirement for fertiliser or pesticides, it offers considerable advantages over conventional 'industrial' agriculture. Nevertheless, although research on intercropping has been conducted since the late 19th century, that work became largely invisible after 1945 as the rapid rise of industrial agriculture erased alternative approaches from view. Since the 1970s, however, intercropping and other alternatives have reappeared on the research agenda as the damaging impacts of industrial agriculture have become evident. [ABSTRACT FROM AUTHOR]

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Many invasive and some native tree species in North America exhibit strong allelopathic effects that may contribute to their local dominance. Pyrogenic carbon (PyC; including soot, charcoal, and black carbon) is produced by the incomplete combustion of organic matter and is widespread in forest soils. Many forms of PyC have sorptive properties that can reduce the bioavailability of allelochemicals. We investigated the potential for PyC produced by controlled pyrolysis of biomass ("biochar" [BC]) to reduce the allelopathic effects of black walnut (Juglans nigra) and Norway maple (Acer platanoides), a common native tree species and a widespread invasive species in North America, respectively. Seedling growth of two native tree species (Acer saccharinum [silver maple] and Betula papyrifera [paper birch]) in response to leaf‐litter‐incubated soils was examined; litter incubation treatments included leaves of black walnut, Norway maple, and a nonallelopathic species (Tilia americana [American basswood]) in a factorial design with varying dosages; responses to the known primary allelochemical of black walnut (juglone) were also examined. Juglone and leaf litter of both allelopathic species strongly suppressed seedling growth. BC treatments substantially mitigated these effects, consistent with the sorption of allelochemicals; in contrast no positive effects of BC were observed in leaf litter treatments involving controls or additions of nonallelopathic leaf litter. Treatments of leaf litter and juglone with BC increased the total biomass of silver maple by ~35% and in some cases more than doubled the biomass of paper birch. We conclude that BCs have the capacity to largely counteract allelopathic effects in temperate forest systems, suggesting the effects of natural PyC in determining forest community structure, and also the applied use of BC as a soil amendment to mitigate allelopathic effects of invasive tree species. [ABSTRACT FROM AUTHOR]

Existing estimates of methane fluxes from North American wetlands vary widely in both magnitude and distribution. In light of these disagreements, this study uses atmospheric methane observations from the US and Canada to analyze seven different bottom-up, wetland methane estimates reported in a recent model comparison project. We first use synthetic data to explore how well atmospheric observations can constrain wetland fluxes. We find that observation sites can identify an atmospheric pattern from Canadian wetlands but not reliably from US wetlands. The network can also identify the spatial distribution of fluxes in Canada at multi-province spatial scales. Based upon these results, we then use real data to evaluate the magnitude, temporal distribution, and spatial distribution of each model estimate. Most models overestimate the magnitude of fluxes across Canada. Most predict a seasonality that is too narrow, potentially indicating an over-sensitivity to air or soil temperatures. In addition, the LPJ-Bern model has a spatial distribution that is most consistent with atmospheric observations. Unlike most models, LPJ-Bern utilizes land cover maps, not just remote sensing inundation data, to estimate wetland coverage. A flux model with a constant spatial distribution outperforms most other existing flux estimates across Canada. [ABSTRACT FROM AUTHOR]

The incidence of wildfires in the Arctic and subarctic is increasing; in boreal North America, for example, the burned area is expected to increase by 200-300% over the next 50-100 years, which previous studies suggest could have a large effect on cloud microphysics, lifetime, albedo, and precipitation. However, the interactions between smoke particles and clouds remain poorly quantified due to confounding meteorological influences and remote sensing limitations. Here, we use data from several aircraft campaigns in the Arctic and subarctic to explore cloud microphysics in liquid-phase clouds influenced by biomass burning. Median cloud droplet radii in smoky clouds were ~50% smaller than in background clouds. Based on the relationship between cloud droplet number (Nliq) and various biomass burning tracers (BBt) across the multi-campaign dataset, we calculated the magnitude of subarctic and Arctic smoke aerosol-cloud interactions (ACI, where ACI= (1/3)×dln(Nliq)/dln(BBt)) to be ~0.12 out of a maximum possible value of 0.33 that would be obtained if all aerosols were to nucleate cloud 15 droplets. Interestingly, in a separate subarctic case study with low liquid water content (~0.02 gm-3) and very high aerosol concentrations (2000-3000 cm-3) in the most polluted clouds, the estimated ACI value was only 0.06. In this case, competition for water vapor by the high concentration of CCN strongly limited the formation of droplets and reduced the cloud albedo effect, which highlights the importance of cloud feedbacks across scales. Using our calculated ACI values, we estimate that the smoke-driven cloud albedo effect may decrease shortwave radiative flux by 2-4Wm-2 or more under some low and homogeneous cloud cover conditions in the subarctic, although the changes should be smaller in high surface albedo regions of the Arctic. We lastly show evidence to suggest that numerous northern latitude background Aitken particles can interact with combustion particles, perhaps impacting their properties as cloud condensation and ice nuclei. However, the influence of background particles on smoke-driven indirect effects is currently unclear. [ABSTRACT FROM AUTHOR]

With the growing number of open access (OA) mandates, the accurate measurement of OA publishing is an important policy issue. Existing studies have provided estimates of the prevalence of OA publications ranging from 27.9% to 53.7%, depending on the data source and period of investigation. This paper aims at providing a comparison of the proportion of OA publishing as represented in two major bibliometric databases, Web of Science (WoS) and Dimensions, and assesses how the choice of database affects the measurement of OA across different countries. Results show that a higher proportion of publications indexed in Dimensions are OA than those indexed by WoS, and that this is particularly true for publications originating from outside North America and Europe. The paper concludes with a discussion of the cause and consequences of these differences, motivating the use of more inclusive databases when examining OA, especially for publications originating beyond North America and Europe. [ABSTRACT FROM AUTHOR]

Trembling aspen (Populus tremuloides) is one of the major species within Populus, a predominant genus of hardwoods in North America. However, its utilization has been limited to pulp and paper or wood-based composite boards. This study aimed at evaluating the major physical and mechanical properties of trembling aspen lumber, with an ultimate objective of using this species to produce engineered wood products (EWPs). The testing materials consisted of 2 × 4 (38 mm × 89 mm) trembling aspen lumber pieces in lengths of 8, 10, and 12 feet (2.44, 3.05, and 3.66 m) with two visual grades, select structural (SS) and No. 2. Machine Stress-Rated (MSR), and longitudinal stress wave (LSW), edgewise third-point bending (EWB), and axial tension tests were conducted on the lumber. It was found that, (1) by increasing the maximum knot size by a half-inch from one-quarter inch, the minimum modulus of elasticity (MOE) measured using the MSR, the mean, and the fifth-percentile ultimate tensile strength (UTS) decreased by about 8.8%, 20.1%, and 29.8%, respectively. (2) Approximately 44% of the trembling aspen lumber met the 1450f-1.3E grade for MSR lumber, and 62% qualified for the 1200f-1.2E grade. (3) There was a great potential for manufacturing cross-laminated timber (CLT) of grade E3, with a rejection rate of about 29%. (4) The mean UTS and MOE values of the SS-grade trembling aspen lumber were 22.88 MPa and 9519 MPa, respectively, being 25.5% and 11.3% lower than that of Spruce–Pine–Fir (S-P-F) lumber. The fifth-percentile UTS and MOE values were 11.57 MPa and 7404 MPa, respectively, marking a decrease of 13.3% and 1.5% compared to the S-P-F lumber. (5) The oven-dried specific gravity (SG) of the trembling aspen wood was 0.40, which was about 3.5% larger than the value provided in the Wood Handbook. [ABSTRACT FROM AUTHOR]

Objectives: This paper aims to systematically review the impact of legislative framework changes in North America and Europe on adolescent cannabis use. It not only seeks to examine the prevalence of adolescent marijuana use following legislative changes but also to identify the driving forces behind fluctuations in use and to address the gaps left by previous studies. Methods: A systematic literature review was conducted in selected databases. After screening English-language publications dating from 2013 to 2023 (n = 453 studies), 24 met the inclusion criteria. Articles were considered if they analyzed the impact of legislative changes on adolescent cannabis use in countries across North America and Europe. Synthesis: The overall findings suggest an inconsistency regarding the prevalence of cannabis use among youth and adolescents following policy changes. The effects of modifications in cannabis policies on marijuana consumption are complex and influenced by various factors. These include the details of legislation, societal perspectives, enforcement methods, socioeconomic status, and cultural background. Conclusions: The results of this analysis reveal a nuanced reality. Although research suggests a rise in cannabis use after legalization, there are variations in the outcomes observed. This highlights the significance of considering context and demographics. Moreover, studies shed light on how specific policy changes, such as depenalization, can affect cannabis use. [ABSTRACT FROM AUTHOR]

Microbiota restoration therapy has become a standard treatment for recurrent Clostridioides difficile infection (rCDI). In this article, we review the studies supporting the licensure of two live biotherapeutic products (LBPs) designed to prevent rCDI and to provide clinicians with a perspective on their differences. PubMed was reviewed on 1 October 2023, for all papers published concerning the current Food and Drug Administration allowance of the use of fecal microbiota transplantation (FMT) and the studies that led to the licensure of RBX2660 (REBYOTA™), generic name, fecal microbiota, live-jslm, and SER-109 (VOWST™), generic name, fecal microbiota spores, live-brpk. OpenBiome continues to produce fecal products for patients with rCDI at their treatment sites, and the American Gastroenterology Association has a National Registry focused on long-term safety of administering fecal microbiota products. The science behind the licensing of fecal microbiota, live-jslm, a consortium of fecal anaerobes found in stool augmented with strains of Bacteroidetes and fecal microbiota spores, live-brpk, a mixture of 50 species of purified Firmicutes spores is reviewed. Both products appear to be safe in clinical trials and effective in reducing rCDI episodes by mechanisms established for FMT, including normalization of α- and β-diversity of the microbiome and by increasing fecal secondary bile acids. The different makeup of the two LBPs suggests that rCDI responds to a variety of engrafting microbiota which explains why nearly all donors in FMT of rCDI are generally effective. Fecal microbiota, live-jslm has also been shown to successfully treat rCDI in elderly patients with advanced comorbidities. With the licensure of two novel LBPs, we are entering a new phase of microbiota replacement therapy. Having standardized manufacturing and proper monitoring of products, harnessing the microbiome to control and prevent disease has a new beginning. Plain language summary: Licensure of two new live biotherapeutic products to treat recurrent C difficile infection is changing the landscape for treatment of this common and often serious infection Microbiota replacement therapy is the most effective way to prevent multiple recurrences of C difficile infection. The article discusses where fecal microbiota transplantation is available in North America. The major focus is on two recently licensed live biotherapeutic products, RBX2660 (REBYOTA), generic name fecal microbiota, live-jslm and SER-109 (VOWST), generic fecal microbiota spores, live-brpk, manufactured under standardized methods which should be safer and more standardized in response. The article compares the new LBPs for safety, effectiveness, cost to help clinicians make decisions. The licensure and availability of two safe and effective standardized and regulated biotherapies, fecal microbiota, live-jslm and fecal microbiota spores, live-brpk, for preventing rCDI is a critical advance in medical management. Both treatments were shown to cure rCDI, to normalize the microbiome of the treated patients by reducing proportions of proinflammatory Enterobacteriaceae and increasing the α- and β-diversity of the microbiome, and to convert primary bile acids to C. difficile -inhibiting secondary bile acids in fecal samples. Both products included follow-up studies show durable cure without important short-term adverse events. The two recently licensed LBP differ in a number of ways. Fecal microbiota, live-jslm is a broad consortium of microbiota expected in a healthy donor fecal samples, including all the major phyla including Firmicutes. It is augmented with strains of Bacteroidetes, while fecal microbiota spores, live-brpk is ethanol washed spores exclusively within the phylum of Firmicutes. The fact that both products are effective in preventing rCDI support the idea that bacterial restoration in rCDI can be achieved by transplantation of a variety of different microbiota. This is seen in FMT for rCDI where it is generally accepted that all healthy adults are suitable donors and large number of donors can be included unscreened for microbiome diversity in a stool bank such as OpenBiome. When treating conditions other than CDI, the specific makeup of an LBP may need to be adjusted. One way around the unique microbiome requirements of non-CDI illnesses with dysbiosis is to administer FMT product derived from multiple donors. Evidence developed and presented here indicate that the two new LBPs are effective in treating rCDI, although head-to-head comparisons have not been carried out. fecal microbiota, live-jslm is a more traditional microbiome restoration product employing a full range of microbiota. fecal microbiota spores, live-brpk is novel in design and is based on the selection of Firmicutes spores with a narrower range of bioactivity. The future of microbiota-therapy has gotten brighter with the licensure of fecal microbiota, live-jslm and fecal microbiota spores, live-brpk. [ABSTRACT FROM AUTHOR]

The traditional approach to formulating building codes often is slow and labor-intensive, and may struggle to keep pace with the rapid evolution of technology and domain findings. Overcoming such challenges necessitates a methodology that streamlines the modernization of codal provisions. This paper proposes a machine learning (ML) approach to append a variety of codal provisions, including those of empirical, statistical, and theoretical natures. In this approach, a codal provision (i.e., equation) is analyzed to trace its properties (e.g., engineering intuition and causal logic). Then a ML model is tailored to preserve the same properties and satisfy a collection of similarity and performance measures until declared equivalent to the provision at hand. The resulting ML model harnesses the predictive capabilities of ML while arriving at predictions similar to the codal provision used to train the ML model, and hence it becomes possible to use in lieu of the codal expression. This approach was examined successfully for seven structural engineering phenomena contained within various building codes, including those in North America and Australia. The findings suggest that the proposed approach could lay the groundwork for implementing ML in the development of future building codes. [ABSTRACT FROM AUTHOR]

Beta-lactam allergy is reported in 5–10% of children in North America, but up to 94–97% of patients are deemed not allergic after allergist assessment. The utility of standardized skin testing for penicillin allergy in the pediatric population has been recently questioned. Oral drug challenges when appropriate, are preferred over skin testing, and can definitively rule out immediate, IgE-mediated drug allergy. To our knowledge, this is the only pediatric study to assess the reliability of a penicillin allergy stratification tool using a paper and electronic clinical algorithm. By using an electronic algorithm, we identified 61 patients (of 95 deemed not allergic by gold standard allergist decision) as low risk for penicillin allergy, with no false negatives and without the need for allergist assessment or skin testing. In this study, we demonstrate that an electronic algorithm can be used by various pediatric clinicians when evaluating possible penicillin allergy to reliably identify low risk patients. We identified the electronic algorithm was superior to the paper version, capturing an even higher percentage of low risk patients than the paper version. By developing an electronic algorithm to accurately assess penicillin allergy risk based on appropriate history, without the need for diagnostic testing or allergist assessment, we can empower non-allergist health care professionals to safely de-label low risk pediatric patients and assist in alleviating subspecialty wait times for penicillin allergy assessment. [ABSTRACT FROM AUTHOR]

This paper describes the fabrication of cicada-wing-inspired antimicrobial surfaces using Glancing Angle Deposition (GLAD). From the study of an annual cicada (Neotibicen Canicularis, also known as dog-day cicada) in North America, it is found that the cicada wing surfaces are composed of unique three-dimensional (3D) nanofeature arrays, which grant them extraordinary properties including antimicrobial (antifouling) and antireflective. However, the morphology of these 3D nanostructures imposes challenges in artificially synthesizing the structures by utilizing and scaling up the template area from nature. From the perspective of circumventing the difficulties of creating 3D nanofeature arrays with top-down nanofabrication techniques, this paper introduces a nanofabrication process that combines bottom-up steps: self-assembled nanospheres are used as the bases of the features, while sub-100 nm pillars are grown on top of the bases by GLAD. Scanning electron micrographs show the resemblance of the synthesized cicada wing mimicry samples to the actual cicada wings, both quantitatively and qualitatively. The synthetic mimicry samples are hydrophobic with a water contact angle of 125˚. Finally, the antimicrobial properties of the mimicries are validated by showing flat growth curves of Escherichia coli (E. coli) and by direct observation under scanning electron microscopy (SEM). The process is potentially suitable for large-area antimicrobial applications in food and biomedical industries. [ABSTRACT FROM AUTHOR]

Mitigating CO2 emissions from long-haul commercial trucking is a major challenge that must be addressed to achieve substantial reductions in greenhouse gas (GHG) emissions from the transportation sector. Extensive recent research and development programs have shown how significant near-term reductions in GHGs from commercial vehicles can be achieved by combining technological advances. This paper reviews progress in technology for engine efficiency improvements, vehicle resistance and drag reductions, and the introduction of hybrid electric powertrains in long-haul trucks. The results of vehicle demonstration projects by major vehicle manufacturers have shown peak brake thermal efficiency of 55% in heavy-duty diesel engines and have demonstrated freight efficiency improvements of 150% relative to a 2009 baseline in North America. These improvements have been achieved by combining multiple incremental improvements in both engine and vehicle technologies. Powertrain electrification through hybridization has been shown to offer some potential reductions in fuel consumption. These potential benefits depend on the vehicle use, the details of the powertrain design, and the duty cycle. To date, most papers have focused on standard drive cycles, leaving a research gap in how hybrid electric powertrains would be designed to minimize fuel consumption over real-world drive cycles, which are essential for a reliable powertrain design. The results of this paper suggest that there is no "one-size-fits-all" solution to reduce the GHGs in long-haul trucking, and a combination of technologies is required to provide an optimum solution for each application. [ABSTRACT FROM AUTHOR]

Objective: To assess how and to what extent socioeconomic status and ethnicity/race of participants are reported in randomized controlled trials (RCTs) on systemic sclerosis (SSc), and to estimate the representativeness of different ethnic/racial groups in SSc RCTs. Methods: We searched all published RCTs on SSc indexed in PubMed. We retrieved information on main features of RCTs published from 2000 onward and recorded for each study whether race/ethnicity was reported; how ethnicity/race was defined and assigned; and the number of patients included for each racial/ethnic group. Multivariable logistic regression was used to identify factors associated with race/ethnicity reporting. Proportion of races/ethnicities included in US‐based RCTs on SSc was examined and compared with US demographic data. Results: We included 106 studies, mostly conducted in Europe (42%) or North America (25%), published after 2010 (74%), and enrolling a total of 6,693 patients. About one‐third of studies provided information about race/ethnicity, with no improved reporting over time. Only 2 papers reported patient's socioeconomic status. Study location (US or intercontinental) was the only significant factor associated with a better reporting of race/ethnicity in multivariable analysis. In studies where race/ethnicity was reported, White patients were mostly represented (79%), followed by Asian (7%), and African American (6%). In the sensitivity analysis limited to studies from the US, underrepresentation of African American patients was observed in the 2000–2010 time period, but not later. Conclusion: Documentation of race/ethnicity and socioeconomic status is poor in RCTs on SSc. More effort should be made to document race/ethnicity and socioeconomic status and to promote diversity in SSc RCTs. [ABSTRACT FROM AUTHOR]