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This paper addresses the need for a new analytical framework to reach a thorough understanding of the outcomes of unequal trade integration, in North America and beyond. To achieve this goal, it was divided in four main sections: the deconstruction of the orthodox argument of free trade areas; the assessment of the contrasting outcomes of NAFTA; an overview of relevant literature; and the delineation of an interdisciplinary agenda. The hypothesis is that the lack of theoretical certainty is due, in parts, to the causal opening of the object of study and to the scarce interaction of specialties. [ABSTRACT FROM AUTHOR]