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This paper reports the discovery of a series of computational social media accounts (Fanbots) on Twitter that may have played a critical role in sustaining the entrepreneurial narratives of Tesla, the electric-vehicle maker. From 2010 to 2020—a period of trial, error, and eventual success for Tesla—these computational agents generated pro-firm tweets (Corporate Computational Propaganda, CCP), accounting for more than 10% of the total Twitter activity that included the cashtag, $TSLA, and 23% of activity that included the hashtag, #TSLA. Though similar to programmed social media content in the political sphere, the activities of these accounts predate the existence of political computational propaganda associated with foreign support for, for instance, Brexit in the United Kingdom (2016) and Donald Trump in the United States (2016). The paper (a) characterizes the extent of Fanbot content in two large Tesla tweet corpora, (b) identifies possible motivations for the creation of these accounts in relation to the firm’s entrepreneurial narratives, and (c) explores possible mechanisms by which the Fanbots might have acted. Although we are unable to directly observe the source or stated purpose of these accounts, based upon the timing of Fanbot creation and other indirect indicators, we infer that these accounts and the social media activity they generated were intended to influence social perception of Tesla. The conclusion assesses the generalizability of a Fanbot-based strategy, highlighting contextual limitations, while also pointing to ways that firms may already be using CCP to manage social approval in emerging-industry contexts.

In this paper, we show how volume rendering with a Programmable Transfer Function can be used for the effective and comprehensible visualization of WiFi signals. A traditional transfer function uses a low-dimensional lookup table to map the volumetric scalar field to color and opacity. In this paper, we present the concept of a Programmable Transfer Function. We then show how generalizing traditional lookup-based transfer functions to Programmable Transfer Functions enables us to leverage view-dependent and real-time attributes of a volumetric field to depict the data variations of WiFi surfaces with low and high-frequency components. Our Programmable Transfer Functions facilitate interactive knowledge discovery and produce meaningful visualizations.

Spatiotemporal prediction of crime is crucial for public safety and smart cities operation. As crime incidents are distributed sparsely across space and time, existing deep-learning methods constrained by coarse spatial scale offer only limited values in prediction of crime density. This paper proposes the use of deep inception-residual networks (DIRNet) to conduct fine-grained, theft-related crime prediction based on non-emergency service request data (311 events). Specifically, it outlines the employment of inception units comprising asymmetrical convolution layers to draw low-level spatiotemporal dependencies hidden in crime events and complaint records in the 311 dataset. Afterward, this paper details how residual units can be applied to capture high-level spatiotemporal features from low-level spatiotemporal dependencies for the final prediction. The effectiveness of the proposed DIRNet is evaluated based on theft-related crime data and 311 data in New York City from 2010 to 2015. The results confirm that the DIRNet obtains an average F1 of 71%, which is better than other prediction models.

Iran is suffering from a state of water bankruptcy. Several factors have contributed to the current water resources bankruptcy, ranging from anthropogenic impacts, such as an inefficient agricultural sector and aggressive withdrawal of groundwater, to climatological impacts. This paper suggests that water resources mismanagement in Iran should be evaluated beyond the policy-makers decisions, as it recognizes that the bankruptcy has been intensified due to the structural and institutional form of the political system in Iran. This study discusses the roots of the water bankruptcy and identifies four major shortcomings caused by the political system: (1) the absence of public engagement due to the lack of a democratic and decentralized structure; (2) adopting ideological policies in domestic and foreign affairs; (3) conflicts of interest and the multiplicity of governmental policy-makers and sectors; and (4) a state-controlled, resource-dependent economy. Through the development of a generic causal model, this study recommends a systematic transition towards a democratic, decentralized, non-ideological, and economically diverse political governance as the necessary–but not necessarily sufficient–adaptive and sustainable solution for mitigating the impacts of water resources bankruptcy in Iran. The insights highlighted in this paper could be employed to inform water resources decision-makers and political actors in other non-democratic and ideological political structures struggling with a water resources crisis or bankruptcy.

In the context of choice with limited consideration, where the decision-maker may not pay attention to all available options, the consideration function of a decision maker is path-independent if her choice cannot be manipulated by the presentation of the choice set. This paper characterizes a model of choice with limited consideration with path independence, which is equivalent to a consideration function that satisfies both the attention filter and consideration filter properties from Masatlioglu et al. (2012) and Lleras et al. (2017), respectively. Despite the equivalence of path-independent consideration with the consideration structures from these two papers, we show that, to have a choice with limited consideration that is path-independent, satisfying both axioms on the choice function that characterize choice limited consideration with attention and consideration filters unilaterally (from Masatlioglu et al. (2012) and Lleras et al. (2017)) is necessary but not sufficient.

This paper explores the uniaxial tensile creep response of acrylic-based pressure-sensitive adhesive (PSA), which exhibits a unique multi-phase creep response that does not have the classical steady-state region due to multiple transitions caused by several competing mechanisms: (i) cavity nucleation and growth in the interior of the adhesive material of the PSA system, as well as at the interfaces between the PSA and the substrate; (ii) fibrillation of the bulk adhesive, and (iii) interfacial mechanical locking between the adhesive and the bonding substrate. This results in multiple regimes of strain hardening and strain softening, evidenced by multiple regions of steady-state creep, separated by strong transitions in the creep rates. This complex, multi-phase, nonlinear creep response cannot be described by conventional creep constitutive models commonly used for polymers in commercial finite element codes. Accordingly, based on the empirical uniaxial tensile creep response and the mechanisms behind it, a new mechanistic model was proposed. This is capable of quantitatively capturing the characteristic features of the multiphase creep response of single-layered PSA joints as a function of viscoelastic bulk properties and free energy of the PSA material, substrate surface roughness, and interfacial surface energy between the adhesive and substrate. This is the first paper to present the modeling approach for capturing unique multi-phase creep behavior of PSA joint under tensile loading.

Iran is suffering from a state of water bankruptcy. Several factors have contributed to the current water resources bankruptcy, ranging from anthropogenic impacts, such as an inefficient agricultural sector and aggressive withdrawal of groundwater, to climatological impacts. This paper suggests that water resources mismanagement in Iran should be evaluated beyond the policy-makers decisions, as it recognizes that the bankruptcy has been intensified due to the structural and institutional form of the political system in Iran. This study discusses the roots of the water bankruptcy and identifies four major shortcomings caused by the political system: (1) the absence of public engagement due to the lack of a democratic and decentralized structure; (2) adopting ideological policies in domestic and foreign affairs; (3) conflicts of interest and the multiplicity of governmental policy-makers and sectors; and (4) a state-controlled, resource-dependent economy. Through the development of a generic causal model, this study recommends a systematic transition towards a democratic, decentralized, non-ideological, and economically diverse political governance as the necessary–but not necessarily sufficient–adaptive and sustainable solution for mitigating the impacts of water resources bankruptcy in Iran. The insights highlighted in this paper could be employed to inform water resources decision-makers and political actors in other non-democratic and ideological political structures struggling with a water resources crisis or bankruptcy.

Water management and governance continues to rely on the scientific and engineering principles of the hydrologic cycle for decision-making on policies and infrastructure choices. This over-reliance on hydrologic-based, technocratic, command-and-control management and governance tends to discount and overlook the political, social, cultural, and economic factors that shape water-society relationships. This paper utilizes an alternative framework, the hydrosocial cycle, to analyze how water and society shape each other over time. In this paper, the hydrosocial framework is applied to stormwater management in the United States. Two hydrosocial case studies centered on rain and stormwater are investigated to highlight how stormwater management can benefit from a hydrosocial approach. The insights and implications from these case studies are then applied to stormwater management by formulating key questions that arise under the hydrosocial framework. These key questions are significant to progressing stormwater management to more sustainable, resilient, and equitable outcomes for environmental and public safety and health. This paper frames a conversation for incorporating the hydrosocial framework into stormwater management and demonstrates the need for an interdisciplinary approach to water management and governance issues.

Human variability related to physical, cognitive, socio-demographic, and other factors can contribute to large differences in human performance. Quantifying population heterogeneity can be useful for designers wishing to evaluate design parameters such that a system design is robust to this variability. Comprehensively integrating human variability in the design process poses many challenges, such as limited access to a statistically representative population and limited data collection resources. This paper discusses two virtual population modeling approaches intended to be performed prior to in-person design validation studies to minimize these challenges by: (1) targeting recruitment of representative population strata and (2) reducing the candidate design parameters being validated in the target population. The first approach suggests the use of digital human models, virtual representations of humans that can simulate system interaction to eliminate candidate design parameters. The second approach suggests the use of existing human databases to identify relevant human characteristics for representative recruitment strata in subsequent studies. Two case studies are presented to demonstrate each approach, and the benefits and limitations of each are discussed. This paper demonstrates the benefit of modeling prior to conducting in-person human performance studies to minimize resource burden, which has significant implications on early design stages.

Group testing idea is an efficient approach to detect prevalence of an infection in the test samples taken from a group of individuals. It is based on the idea of pooling the test samples and performing tests to the mixed samples. This approach results in possible reduction in the required number of tests to identify infections. Classical group testing works consider static settings where the infection statuses of the individuals do not change throughout the testing process. In our paper, we study a dynamic infection spread model, inspired by the discrete time SIR model, where infections are spread via non-isolated infected individuals, while infection keeps spreading over time, a limited capacity testing is performed at each time instance as well. In contrast to the classical, static group testing problem, the objective in our setup is not to find the minimum number of required tests to identify the infection status of every individual in the population, but to control the infection spread by detecting and isolating the infections over time by using the given, limited number of tests. In order to analyze the performance of the proposed algorithms, we focus on the average-case analysis of the number of individuals that remain non-infected throughout the process of controlling the infection. We propose two dynamic algorithms that both use given limited number of tests to identify and isolate the infections over time, while the infection spreads, while the first algorithm is a dynamic randomized individual testing algorithm, in the second algorithm we employ the group testing approach similar to the original work of Dorfman. By considering weak versions of our algorithms, we obtain lower bounds for the performance of our algorithms. Finally, we implement our algorithms and run simulations to gather numerical results and compare our algorithms and theoretical approximation results under different sets of system parameters.

This paper presents the entropic damage indicators for metallic material fatigue processes obtained from three associated energy dissipation sources. Since its inception, reliability engineering has employed statistical and probabilistic models to assess the reliability and integrity of components and systems. To supplement the traditional techniques, an empirically-based approach, called physics of failure (PoF), has recently become popular. The prerequisite for a PoF analysis is an understanding of the mechanics of the failure process. Entropy, the measure of disorder and uncertainty, introduced from the second law of thermodynamics, has emerged as a fundamental and promising metric to characterize all mechanistic degradation phenomena and their interactions. Entropy has already been used as a fundamental and scale-independent metric to predict damage and failure. In this paper, three entropic-based metrics are examined and demonstrated for application to fatigue damage. We collected experimental data on energy dissipations associated with fatigue damage, in the forms of mechanical, thermal, and acoustic emission (AE) energies, and estimated and correlated the corresponding entropy generations with the observed fatigue damages in metallic materials. Three entropic theorems—thermodynamics, information, and statistical mechanics—support approaches used to estimate the entropic-based fatigue damage. Classical thermodynamic entropy provided a reasonably constant level of entropic endurance to fatigue failure. Jeffreys divergence in statistical mechanics and AE information entropy also correlated well with fatigue damage. Finally, an extension of the relationship between thermodynamic entropy and Jeffreys divergence from molecular-scale to macro-scale applications in fatigue failure resulted in an empirically-based pseudo-Boltzmann constant equivalent to the Boltzmann constant.

This paper analyzed quarterly longitudinal data for 64,800 1 × 1 degree grids during 2000–2019 on sea surface temperatures, sea ice concentrations, and ocean surface current zonal and meridional velocities in the Northern and Southern hemispheres. The methodological framework addressed the processing of remote sensing signals, interdependence between sea surface temperatures and sea ice concentrations, and combining zonal and meridional velocities as the eddy kinetic energy. Dynamic and static random effects models were estimated by maximum likelihood and stepwise methods, respectively, taking into account the unobserved heterogeneity across grids. The main findings were that quarterly sea surface temperatures increased steadily in the Northern hemisphere, whereas cyclical patterns were apparent in Southern hemisphere; sea ice concentrations declined in both hemispheres. Second, sea surface temperatures were estimated with large negative coefficients in the models for sea ice concentrations for the hemispheres; previous sea ice concentrations were negatively associated with sea surface temperatures, indicating feedback loops. Third, sea surface temperatures were positively and significantly associated with eddy kinetic energy in Northern hemisphere. Overall, the results indicated the importance of reducing sea surface temperatures via reductions in greenhouse gas emissions and the dumping of pollutants into oceans for maintaining sea ice concentrations and enhancing global sustainability.

Food safety issues are a worldwide concern. Pathogens, toxins, pesticides, veterinary drugs, heavy metals, and illegal additives are frequently reported to contaminate food and pose a serious threat to human health. Conventional detection methods have difficulties fulfilling the requirements for food development in a modern society. Therefore, novel rapid detection methods are urgently needed for on-site and rapid screening of massive food samples. Due to the extraordinary properties of nanozymes and aptamers, biosensors composed of both of them provide considerable advantages in analytical performances, including sensitivity, specificity, repeatability, and accuracy. They are considered a promising complementary detection method on top of conventional ones for the rapid and accurate detection of food contaminants. In recent years, we have witnessed a flourishing of analytical strategies based on aptamers and nanozymes for the detection of food contaminants, especially novel detection models based on the regulation by single-stranded DNA (ssDNA) of nanozyme activity. However, the applications of nanozyme-based aptasensors in food safety are seldom reviewed. Thus, this paper aims to provide a comprehensive review on nanozyme-based aptasensors in food safety, which are arranged according to the different interaction modes of ssDNA and nanozymes: aptasensors based on nanozyme activity either inhibited or enhanced by ssDNA, nanozymes as signal tags, and other methods. Before introducing the nanozyme-based aptasensors, the regulation by ssDNA of nanozyme activity via diverse factors is discussed systematically for precisely tailoring nanozyme activity in biosensors. Furthermore, current challenges are emphasized, and future perspectives are discussed.

Adolescent years are a time of joy and can represent a challenge for parents and youth, especially for immigrants to the US who are adjusting to their host country. Programs focusing on family skills and positive youth development (PYD) can contribute to youth wellbeing especially, however, few exist for low-income immigrant families. (1) Background: The major goals of this project are to strengthen both PYD and healthy parenting practices by implementing an evidence-informed program, Familias Activas. A theory of change guided the development of Familias Activas in which three factors: parent training, positive youth development, and youth physical activity sessions (soccer) aimed to improve Latinx youth mental health. Youth participated in weekly soccer practices led by trained soccer coaches while parents/caregivers attended parent education. Both sessions lasted eight weeks. (2) Method: We describe the formative stage of the research project as well as the pilot implementation of the Familias Activas program, which provides critical insights for the development of a PYD program. (3) Results: Evaluation surveys were administered to youth and their parents. Thirty youths and sixteen parents completed the survey. The Kidscreen scale had a mean for most items ranging from 3.6 to 4.2. Participating youth were 11 years old and most affirmed they were Latinx. The feasibility program quality mean was 4.2 indicating an overall positive result for the pilot program.. Implications of PYD programs for Latinx youth are discussed. (4) Conclusions: The current paper presents a model for positively influencing the physical and mental wellbeing of Latinx youth and their parents. The model is culturally responsive in its involvement of both parents and youth in programming.

In recent years, Global Navigation Satellite System (GNSS) radio occultation (RO) has become a critical observation system for global operational numerical weather prediction. Constellation Observing System for Meteorology, Ionosphere, Climate (COSMIC) 2 (COSMIC-2) has been a backbone RO mission for NOAA. NOAA also began to purchase RO data from commercial sources in 2020. To ensure the consistent quality of RO data from different sources, NOAA Center for Satellite Applications and Research (STAR) has developed capabilities to process all available RO data from different missions. This paper describes the STAR RO processing systems which convert the pseudo-range and carrier phase observations to excess phases and bending angles (BAs). We compared our COSMIC-2 data products with those processed by the University Corporation for Atmospheric Research (UCAR) COSMIC Data Analysis and Archive Center (CDAAC). We processed more than twelve thousand COSMIC-2 occultation profiles. Our results show that the excess phase difference between UCAR and STAR is within a few centimeters at high altitudes, although the difference increases towards the lower atmosphere. The BA profiles derived from the excess phase are consistent with UCAR. The mean relative BA differences at impact height from 10 to 30 km are less than 0.1% for GLObal NAvigation Satellite System (GLONASS) L2C signals and Global Positioning System (GPS) L2C and L2P signals. The standard deviations are 1.15%, 1.15%, and 1.32% for GLONASS L2C signal and for GPS L2C and L2P signals, respectively. The BA profiles agree with those derived from European Center for Medium-range Weather Forecast (ECMWF) reanalysis version 5 (ERA5). The Signal-to-Noise-Ratio (SNR) plays an essential role in the processing. The STAR BA profiles with higher L1 SNRs (L1 at 80 km) tend to yield more consistent results than those from UCAR, with a negligible difference and a smaller deviation than lower SNR profiles. Profiles with lower SNR values t

Terrestrial snow is a vital freshwater resource for more than 1 billion people. Remotely-sensed snow observations can be used to retrieve snow mass or integrated into a snow model estimate; however, optimally leveraging remote sensing observations of snow is challenging. One reason is that no single sensor can accurately measure all types of snow because each type of sensor has its own unique limitations. Another reason is that remote sensing data is inherently discontinuous across time and space, and that the revisit cycle of remote sensing observations may not meet the requirements of a given snow applications. In order to quantify the feasible availability of remotely-sensed observations across space and time, this study simulates the sensor coverage for a suite of hypothetical snow sensors as a function of different orbital configurations and sensor properties. The information gleaned from this analysis coupled with a dynamic snow binary map is used to evaluate the efficiency of a single sensor (or constellation) to observe terrestrial snow on a global scale. The results show the efficacy achievable by different sensors over different snow types. The combination of different orbital and sensor configurations is explored to requirements of remote sensing missions that have 1-day, 3-day, or 30-day repeat intervals. The simulation results suggest that 1100 km, 550 km, and 200 km are the minimum required swath width for a polar-orbiting sensor to meet snow-related applications demanding a 1-day, 3-day, and 30-day repeat cycles, respectively. The results of this paper provide valuable input for the planning of a future global snow mission.

This paper presents a novel computational algorithm to estimate blood volume decompensation state based on machine learning (ML) analysis of multi-modal wearable-compatible physiological signals. To the best of our knowledge, our algorithm may be the first of its kind which can not only discriminate normovolemia from hypovolemia but also classify hypovolemia into absolute hypovolemia and relative hypovolemia. We realized our blood volume classification algorithm by (i) extracting a multitude of features from multi-modal physiological signals including the electrocardiogram (ECG), the seismocardiogram (SCG), the ballistocardiogram (BCG), and the photoplethysmogram (PPG), (ii) constructing two ML classifiers using the features, one to classify normovolemia vs. hypovolemia and the other to classify hypovolemia into absolute hypovolemia and relative hypovolemia, and (iii) sequentially integrating the two to enable multi-class classification (normovolemia, absolute hypovolemia, and relative hypovolemia). We developed the blood volume decompensation state classification algorithm using the experimental data collected from six animals undergoing normovolemia, relative hypovolemia, and absolute hypovolemia challenges. Leave-one-subject-out analysis showed that our classification algorithm achieved an F1 score and accuracy of (i) 0.93 and 0.89 in classifying normovolemia vs. hypovolemia, (ii) 0.88 and 0.89 in classifying hypovolemia into absolute hypovolemia and relative hypovolemia, and (iii) 0.77 and 0.81 in classifying the overall blood volume decompensation state. The analysis of the features embedded in the ML classifiers indicated that many features are physiologically plausible, and that multi-modal SCG-BCG fusion may play an important role in achieving good blood volume classification efficacy. Our work may complement existing computational algorithms to estimate blood volume compensatory reserve as a potential decision-support tool to provide guidance on context-sen

The research in this paper entails the design of material systems with tunable energy-absorbing properties. Hollow glass microspheres of different densities are layered using dry powder printing and subsequently sintered to form a cellular structure. The tunability of the bilayer foams is investigated using various combinations of hollow microspheres with different densities and different thickness ratios of the layers. The mechanical responses to quasi-static uniaxial compression of the bilayer foams are also investigated. These bilayer samples show different mechanical responses from uniform samples with a distinctive two-step stress–strain profile that includes a first and second plateau stress. The strain where the second plateau starts can be tuned by adjusting the thickness ratio of the two layers. The resulting tunable stress–strain profile demonstrates tunable energy absorption. The tunability is found to be more significant if the density values of each layer differ largely. For comparison, bilayer samples are fabricated using epoxy at the interface instead of a sintering process and a different mechanical response is shown from a sintered sample with the different stress–strain profile. Designing the layered foams allows tuning of the stress–strain profile, enabling desired energy-absorbing properties which are critical in diverse impact conditions.

Designers perform early-stage formative usability tests with low-fidelity prototypes to improve the design of new products. This low-tech prototype style reduces the manufacturing resources but limits the functions that can be assessed. Recent advances in technology enable designers to create low-fidelity 3D models for users to engage in a virtual environment. Three-dimensional models communicate design concepts and are not often used in formative usability testing. The proposed method discusses how to create a virtual replica of a product by assessing key human interaction steps and addresses the limitations of translating those steps into a virtual environment. In addition, the paper will provide a framework to evaluate the usability of a product in a virtual setting, with a specific emphasis on low-resource online testing in the user population. A study was performed to pilot the subject’s experience with the proposed approach and determine how the virtual online simulation impacted the performance. The study outcomes demonstrated that subjects were able to successfully interact with the virtual replica and found the simulation realistic. This method can be followed to perform formative usability tests earlier and incorporate subject feedback into future iterations of their design, which can improve safety and product efficacy.

It is well-established that increasing demands for fresh water are paving the way for desalination technologies. However, this correlates with an increase in brine production whose treatment and disposal can be complicated and expensive. This paper presents a thermodynamic model to bound the operation and development of a novel Humidification–Dehumidification-based system featuring Zero-Liquid Discharge and off-grid capabilities. The model employs conservation laws to find feasible state points to meet a baseline operation of 10 kg/h of product water separated from a hypersaline feed stream with 100 g/kg salt concentration. The system incurs in a 1039 kWh/m3 energy intensity that can be supplied completely by an electric source or in combination with heating steam. Follow-up sensitivity analysis highlights the robustness of the system in handling variations of 25% in product flowrate and 75% in feed salinity, practically without incurring any additional energy demands. The proposed system operating costs between 72 USD/m3 and 96 USD/m3 are comparable to those of existing brine disposal techniques. Furthermore, an operational map of existing desalination technologies suggests a niche characterized by high recovery rates and high feed salinities that are generally unfulfilled by conventional desalination methods. Overall, the proposed system shows potential for off-grid hypersaline brine treatment. This study sets the stage for future development of physics-based and data-driven predictive models as the proposed system iterates into a pilot plant deployment.

This paper presents the various ways that lithium-ion batteries are being counterfeited, the problems that counterfeit batteries present, how they enter the consumer market, and the difficulties of detection. Simple external visual inspection of the battery is unreliable. As shown in the presented case study, even for the same brand batteries, their internal structures are different. The current counterfeit prevention methods focus on the manufacturing step. To reduce the risk of counterfeit batteries, device manufacturers and retail stores should characterize the batteries they receive. In addition, related authorities or organizations should set standards to enable a universal battery tracking method along the supply chain to prevent counterfeit lithium-ion batteries from entering the market.

Soil moisture operational product system (SMOPS) is developed by National Oceanic and Atmospheric Administration (NOAA) to provide the real-time blended soil moisture (SM) for numeric weather prediction and national water model applications. However, all individual satellite SM data ingested into the current operational SMOPS are scaled to global land data assimilation system (GLDAS) 0–10 cm SM climatology before the combination. As a result, the useful information from the original microwave SM retrievals could be lost, and the GLDAS model errors could be brought into the final SMOPS blended product. In this paper, we propose to scale the individual SM retrievals to the soil moisture active passive (SMAP) data through building regression models. The rescaled individual SM data and the SMAP observations then have similar climatology and dynamics, which allows producing the SMOPScdr (distinguishing with the current operational SMOPSopr) data using an equal-weight averaging approach. With respect to the in situ SM measurements, the developed SMOPScdr is more successful tracking the surface SM status than the individual satellite SM products with significantly decreased errors. The proposed method also preserves the climatology of the reference SMAP data for the period when SMAP is not available, allowing us to produce a long-term SMOPScdr data product.

In order to meet increasing power-dissipation requirements of the electronics industry, compact, low-cost, and lightweight heat exchangers (HXs) are desired. With proper design, materials, and manufacture, polymer composite heat exchangers could meet these requirements. This paper presents a novel crossflow air-to-water, low-cost, and lightweight metal-polymer composite HX. This HX, which is entirely additively manufactured, utilizes a novel cross-media approach that provides direct heat exchange between air and liquid sides by using connecting fins. A robust numerical model was developed, which includes the dimensional effects of additive manufacturing. The study consists of a simplified 3D CFD model based on ellipsoidal-shaped staggered tube banks for the laminar range. It then uses an analytical approach to compute entire HX performance. The model is validated experimentally within 8% for thermal performance, 12% for air-side impedance, and 18% for water-side impedance. Finally, HX is compared with a conventional CPU radiator and performs within 10% of the conventional unit for reasonable flow rates and pressure-drop ranges. Moreover, HX also provides added design and cost advantages over the conventional unit, which makes the HX a potential candidate for electronic cooling applications.

This paper studies the privacy of wireless communications from an eavesdropper that employs a deep learning (DL) classifier to detect transmissions of interest. There exists one transmitter that transmits to its receiver in the presence of an eavesdropper. In the meantime, a cooperative jammer (CJ) with multiple antennas transmits carefully crafted adversarial perturbations over the air to fool the eavesdropper into classifying the received superposition of signals as noise. While generating the adversarial perturbation at the CJ, multiple antennas are utilized to improve the attack performance in terms of fooling the eavesdropper. Two main points are considered while exploiting the multiple antennas at the adversary, namely the power allocation among antennas and the utilization of channel diversity. To limit the impact on the bit error rate (BER) at the receiver, the CJ puts an upper bound on the strength of the perturbation signal. Performance results show that this adversarial perturbation causes the eavesdropper to misclassify the received signals as noise with a high probability while increasing the BER at the legitimate receiver only slightly. Furthermore, the adversarial perturbation is shown to become more effective when multiple antennas are utilized.

Analog circuits are a critical part of industrial electronics and systems. Estimates in the literature show that, even though analog circuits comprise less than 20% of all circuits, they are responsible for more than 80% of faults. Hence, analog circuit fault diagnosis and isolation can be a valuable means of ensuring the reliability of circuits. This paper introduces a novel technique of learning time–frequency representations, using learnable wavelet scattering networks, for the fault diagnosis of circuits and rotating machinery. Wavelet scattering networks, which are fixed time–frequency representations based on existing wavelets, are modified to be learnable so that they can learn features that are optimal for fault diagnosis. The learnable wavelet scattering networks are developed using the genetic algorithm-based optimization of second-generation wavelet transform operators. The simulation and experimental results for the diagnosis of analog circuit faults demonstrates that the developed diagnosis scheme achieves greater fault diagnosis accuracy than other methods in the literature, even while considering a larger number of fault classes. The performance of the diagnosis scheme on benchmark datasets of bearing faults and gear faults shows that the developed method generalizes well to fault diagnosis in multiple domains and has good transfer learning performance, too.

Most deep energy renovation projects focus only on an operating energy reduction and disregard the added embodied energy derived from adding insulation, window/door replacement, and mechanical system replacement or upgrades. It is important to study and address the balance and trade-offs between reduced operating energy and added embodied energy from a whole life cycle perspective to reduce the overall building carbon footprint. However, the added embodied energy and related environmental impact have not been studied extensively. In response to this need, this paper proposes a holistic sustainability index that balances the trade-off between reduced operating energy and added embodied energy. Eight case projects are used to validate the proposed method and calculation. The findings demonstrate that using a balanced sustainability index can reveal results different from a conventional operating energy-centric approach: (a) operating energy savings can be offset by the embodied energy gain, (b) the operating energy savings do not always result in a life cycle emissions reduction, and (c) the sustainability index can vary depending on the priorities the decision makers give to operating carbon, embodied carbon, and operating cost. Overall, the proposed sustainability score can provide us with a more comprehensive understanding of how sustainable the renovation works are from a life cycle carbon emissions perspective, providing a more robust estimation of global warming potential related to building renovation.

The radio occultation technique provides stable atmospheric measurements that can work as a benchmark for calibrating and validating satellite-sounding data. Launched on 25 June 2019, the Constellation Observing System for Meteorology, Ionosphere, and Climate 2 and Formosa Satellite Mission 7 (COSMIC-2/FORMOSAT-7) are expected to produce about 5000 high-quality RO observations daily over the tropics and subtropics. COSMIC-2 constellation consists of 6 Low Earth Orbit (LEO) satellites in 24° inclination orbits at 720 km altitude and distributed mainly between 45°N to 45°S. The COSMIC-2 observations have uniform temporal coverage between 30°N to 30°S. This paper presents an independent inversion algorithm to invert COSMIC-2 geometry and phase data to bending angle and refractivity. We also investigate the quality of Global Navigation Satellite System (GNSS) and LEO position vectors derived from the UCAR COSMIC Data Analysis and Archive Center (CDAAC). The GNSS and LEO position vectors are stable with LEO position variations < 1.4 mm/s. The signal-to-noise ratio (SNR) on the L1 band ranges from 300–2600 v/v with a mean of 1600 v/v. The inversion algorithm developed at NOAA Center for Satellite Applications and Research (STAR) uses the Full Spectrum Inversion (FSI) method to invert COSMIC-2 geometry and phase data to bending angle and refractivity profiles. The STAR COSMIC-2 bending angle and refractivity profiles are compared with in situ radiosonde, the current COSMIC-2 products derived from CDAAC, and the collocated European Center for Medium-Range Weather Forecasts (ECMWF) climate reanalysis data ERA5. The mean bias at 8–40 km altitude among the UCAR, ERA5, and STAR is <0.1% for both bending and refractivity, with a standard deviation in the range of 1.4–2.3 and 0.9–1.1% for bending angles refractivity, respectively. In the lowest 2 km, the RO bias relative to ERA-5 shows a strong latitudinal and SNR dependence.

In this paper, we study a slotted-time system where a base station needs to update multiple users at the same time. Due to the limited resources, only part of the users can be updated in each time slot. We consider the problem of minimizing the Age of Incorrect Information (AoII) when imperfect Channel State Information (CSI) is available. Leveraging the notion of the Markov Decision Process (MDP), we obtain the structural properties of the optimal policy. By introducing a relaxed version of the original problem, we develop the Whittle’s index policy under a simple condition. However, indexability is required to ensure the existence of Whittle’s index. To avoid indexability, we develop Indexed priority policy based on the optimal policy for the relaxed problem. Finally, numerical results are laid out to showcase the application of the derived structural properties and highlight the performance of the developed scheduling policies.

In this paper, we study the corrections to the Friedmann equations due to fast fluctuations in the universe scale factor. Such fast quantum fluctuations were recently proposed as a potential solution to the cosmological constant problem. They also induce strong changes to the current sign and magnitude of the average cosmological force, thus making them one of the potential probable causes of the modification of Newtonian dynamics in galaxy-scale systems. It appears that quantum fluctuations in the scale factor also modify the Friedmann equations, leading to a considerable modification of cosmological evolution. In particular, they give rise to the late-time accelerated expansion of the universe, and they may also considerably modify the effective universe potential.

This paper explores the use of fatty acids in silicone hydrogel contact lenses for extending the release duration of cationic drugs. Drug release kinetics was dependent on the carbon chain length of the fatty acid loaded in the lens, with 12-, 14- and 18-carbon chain length fatty acids increasing the uptake and the release duration of ketotifen fumarate (KTF) and tetracaine hydrochloride (THCL). Drug release kinetics from oleic acid-loaded lenses was evaluated in phosphate buffer saline (PBS) at different ionic strengths (I = 167, 500, 1665 mM); the release duration of KTF and THCL was decreased with increasing ionic strength of the release medium. Furthermore, the release of KTF and THCL in deionized water did not show a burst and was significantly slower compared to that in PBS. The release kinetics of KTF and THCL was significantly faster when the pH of the release medium was decreased from 7.4 towards 5.5 because of the decrease in the relative amounts of oleate anions in the lens mostly populated at the polymer–pore interfaces. The use of boundary charges at the polymer–pore interfaces of a contact lens to enhance drug partition and extend its release is further confirmed by loading cationic phytosphingosine in contact lenses to attract an anionic drug.

This paper presents a finite element implementation of plates and shells for the analysis of flexible multibody systems. The developments are set within the framework of the motion formalism that (1) uses configuration and motion to describe the kinematics of flexible multibody systems, (2) couples their displacement and rotation components by recognizing that configuration and motion are members of the Special Euclidean group, and (3) resolves all tensors components in local frames. The formulation based on the motion formalism (1) provides a theoretical framework that streamlines the formulation of shell elements, (2) leads to governing equations of motion that are objective, intrinsic, and present a reduced order of nonlinearity, (3) improves the efficiency of the solution process, (4) circumvents the shear locking phenomenon that plagues shell formulations based on classical kinematic descriptions, and (5) prevents the occurrence of singularities in the treatment of finite rotation. Numerical examples are presented to illustrate the advantageous features of the proposed formulation.

Lithium-ion battery datasheets, also known as specification sheets, are documents that battery manufacturers provide to define the battery’s function, operational limit, performance, reliability, safety, cautions, prohibitions, and warranty. Product manufacturers and customers rely on the datasheets for battery selection and battery management. However, battery datasheets often have ambiguous and, in many cases, misleading terminology and data. This paper reviews and evaluates the datasheets of 25 different lithium-ion battery types from eleven major battery manufacturers. Issues that customers may face are discussed, and recommendations for developing an informative and valuable datasheet that will help customers procure suitable batteries are presented.

Sensor monitoring networks and advances in big data analytics have guided the reliability engineering landscape to a new era of big machinery data. Low-cost sensors, along with the evolution of the internet of things and industry 4.0, have resulted in rich databases that can be analyzed through prognostics and health management (PHM) frameworks. Several data-driven models (DDMs) have been proposed and applied for diagnostics and prognostics purposes in complex systems. However, many of these models are developed using simulated or experimental data sets, and there is still a knowledge gap for applications in real operating systems. Furthermore, little attention has been given to the required data preprocessing steps compared to the training processes of these DDMs. Up to date, research works do not follow a formal and consistent data preprocessing guideline for PHM applications. This paper presents a comprehensive step-by-step pipeline for the preprocessing of monitoring data from complex systems aimed for DDMs. The importance of expert knowledge is discussed in the context of data selection and label generation. Two case studies are presented for validation, with the end goal of creating clean data sets with healthy and unhealthy labels that are then used to train machinery health state classifiers.

Interactions between soils and climate impact wider environmental sustainability. Soil heterogeneity intricately regulates these interactions over short spatiotemporal scales and therefore needs to be more finely examined. This paper examines how redox heterogeneity at the level of minerals, microbial cells, organic matter, and the rhizosphere entangles biogeochemical cycles in soil with climate change. Redox heterogeneity is used to develop a conceptual framework that encompasses soil microsites (anaerobic and aerobic) and cryptic biogeochemical cycling, helping to explain poorly understood processes such as methanogenesis in oxygenated soils. This framework is further shown to disentangle global carbon (C) and nitrogen (N) pathways that include CO2, CH4, and N2O. Climate-driven redox perturbations are discussed using wetlands and tropical forests as model systems. Powerful analytical methods are proposed to be combined and used more extensively to study coupled abiotic and biotic reactions that are affected by redox heterogeneity. A core view is that emerging and future research will benefit substantially from developing multifaceted analyses of redox heterogeneity over short spatiotemporal scales in soil. Taking a leap in our understanding of soil and climate interactions and their evolving influence on environmental sustainability then depends on greater collaborative efforts to comprehensively investigate redox heterogeneity spanning the domain of microscopic soil interfaces.

Interactions between soils and climate impact wider environmental sustainability. Soil heterogeneity intricately regulates these interactions over short spatiotemporal scales and therefore needs to be more finely examined. This paper examines how redox heterogeneity at the level of minerals, microbial cells, organic matter, and the rhizosphere entangles biogeochemical cycles in soil with climate change. Redox heterogeneity is used to develop a conceptual framework that encompasses soil microsites (anaerobic and aerobic) and cryptic biogeochemical cycling, helping to explain poorly understood processes such as methanogenesis in oxygenated soils. This framework is further shown to disentangle global carbon (C) and nitrogen (N) pathways that include CO2, CH4, and N2O. Climate-driven redox perturbations are discussed using wetlands and tropical forests as model systems. Powerful analytical methods are proposed to be combined and used more extensively to study coupled abiotic and biotic reactions that are affected by redox heterogeneity. A core view is that emerging and future research will benefit substantially from developing multifaceted analyses of redox heterogeneity over short spatiotemporal scales in soil. Taking a leap in our understanding of soil and climate interactions and their evolving influence on environmental sustainability then depends on greater collaborative efforts to comprehensively investigate redox heterogeneity spanning the domain of microscopic soil interfaces.

Recent medical imaging technologies, specifically functional magnetic resonance imaging (fMRI), have advanced the diagnosis of neurological and neurodevelopmental disorders by allowing scientists and physicians to observe the activity within and between different regions of the brain. Deep learning methods have frequently been implemented to analyze images produced by such technologies and perform disease classification tasks; however, current state-of-the-art approaches do not take advantage of all the information offered by fMRI scans. In this paper, we propose a deep multimodal model that learns a joint representation from two types of connectomic data offered by fMRI scans. Incorporating two functional imaging modalities in an automated end-to-end autism diagnosis system will offer a more comprehensive picture of the neural activity, and thus allow for more accurate diagnoses. Our multimodal training strategy achieves a classification accuracy of 74% and a recall of 95%, as well as an F1 score of 0.805, and its overall performance is superior to using only one type of functional data.

This paper takes a well-known observation as its starting point, that is, languages vary with respect to headedness, with the standard head-initial and head-final types well attested. Is there a connection between headedness and the size of a lexical class? Although this question seems quite straightforward, there are formidable methodological and theoretical challenges in addressing it. Building on initial results by several researchers, we refine our methodology and consider the proportion of nouns to simplex verbs (as opposed to light verb constructions) in a varied sample of 33 languages to evaluate the connection between headedness and the size of a lexical class. We demonstrate a robust correlation between this proportion and headedness. While the proportion of nouns in a lexicon is relatively stable, head-final/object-verb (OV)-type languages (e.g., Japanese or Hungarian) have a relatively small number of simplex verbs, whereas head-initial/verb-initial languages (e.g., Irish or Zapotec) have a considerably larger percentage of such verbs. The difference between the head-final and head-initial type is statistically significant. We, then, consider a subset of languages characterized as subject-verb-object (SVO) and show that this group is not uniform. Those SVO languages that have strong head-initial characteristics (as shown by the order of constituents in a set of phrases and word order alternations) are characterized by a relatively large proportion of lexical verbs. SVO languages that have strong head-final traits (e.g., Mandarin Chinese) pattern with head-final languages, and a small subset of SVO languages are genuinely in the middle (e.g., English, Russian). We offer a tentative explanation for this headedness asymmetry, couched in terms of informativity and parsing principles, and discuss additional evidence in support of our account. All told, the fewer simplex verbs in head-final/OV-type languages is an adaptation in response to their particular patt

Surface soil moisture (SSM) plays a critical role in many hydrological, biological and biogeochemical processes. It is relevant to farmers, scientists, and policymakers for making effective land management decisions. However, coarse spatial resolution and complex interactions of microwave radiation with surface roughness and vegetation structure present limitations within active remote sensing products to directly monitor soil moisture variations with sufficient detail. This paper discusses a strategy to use vegetation indices (VI) such as greenness, water stress, coverage, vigor, and growth dynamics, derived from Earth Observation (EO) data for an indirect characterization of SSM conditions. In this regional-scale study of a wetland environment, correlations between the coarse Advanced SCATterometer-Soil Water Index (ASCAT-SWI or SWI) product and statistical measurements of four vegetation indices from higher resolution Sentinel-2 data were analyzed. The results indicate that the mean value of Fraction of Absorbed Photosynthetically Active Radiation (FAPAR) correlates most strongly to the SWI and that the wet season vegetation traits show stronger linear relation to the SWI than during the dry season. The correlation between VIs and SWI was found to be independent of the underlying dominant vegetation classes which are not derived in real-time. Therefore, fine-scale vegetation information from optical satellite data convey the spatial heterogeneity missed by coarse synthetic aperture radar (SAR)-derived SSM products and is linked to the SSM condition underneath for regionalization purposes.

This paper presents a simple and efficient image processing method for estimating the number of coconut trees in the Tonga region using very high spatial resolution data (30 cm) in the blue, green, red and near infrared spectral bands acquired by the WorldView-3 sensor. The method is based on the detection of tree shadows and the further analysis to reject false detection using geometrical properties of the derived segments. The algorithm is evaluated by comparing coconut tree counts derived by an expert through photo-interpretation over 57 randomly distributed (4% sampling rate) segments of 200 m × 200 m over the Vaini region of the Tongatapu island. The number of detected trees agreed within 5% versus validation data. The proposed method was also evaluated over the whole Tonga archipelago by comparing satellite-derived estimates to the 2015 agricultural census data—the total tree counts for both Tonga and Tongatapu agreed within 3%.

Surface downward shortwave radiation (DSR) and photosynthetically active radiation (PAR), its visible component, are key parameters needed for many land process models and terrestrial applications. Most existing DSR and PAR products were developed for climate studies and therefore have coarse spatial resolutions, which cannot satisfy the requirements of many applications. This paper introduces a new global high-resolution product of DSR (MCD18A1) and PAR (MCD18A2) over land surfaces using the MODIS data. The current version is Collection 6.0 at the spatial resolution of 5 km and two temporal resolutions (instantaneous and three-hour). A look-up table (LUT) based retrieval approach was chosen as the main operational algorithm so as to generate the products from the MODIS top-of-atmosphere (TOA) reflectance and other ancillary data sets. The new MCD18 products are archived and distributed via NASA’s Land Processes Distributed Active Archive Center (LP DAAC). The products have been validated based on one year of ground radiation measurements at 33 Baseline Surface Radiation Network (BSRN) and 25 AmeriFlux stations. The instantaneous DSR has a bias of −15.4 W/m2 and root mean square error (RMSE) of 101.0 W/m2, while the instantaneous PAR has a bias of −0.6 W/m2 and RMSE of 45.7 W/m2. RMSE of daily DSR is 32.3 W/m2, and that of the daily PAR is 13.1 W/m2. The accuracy of the new MODIS daily DSR data is higher than the GLASS product and lower than the CERES product, while the latter incorporates additional geostationary data with better capturing DSR diurnal variability. MCD18 products are currently under reprocessing and the new version (Collection 6.1) will provide improved spatial resolution (1 km) and accuracy.

To date, the predominant tools for the evaluation of built environment quality and impact have been surveys, scorecards, or verbal comments—approaches that rely upon user-reported responses. The goal of this research project is to develop, test, and validate a data-driven approach for built environment quality evaluation/validation based upon measurement of real-time emotional responses to simulated environments. This paper presents an experiment that was conducted by combining an immersive virtual environment (virtual reality) and electroencephalogram (EEG) as a tool to evaluate Pre and Post Purple Line development. More precisely, the objective was to (a) develop a data-driven approach for built environment quality evaluation and (b) understand the correlation between the built environment characters and emotional state. The preliminary validation of the proposed evaluation method identified discrepancies between traditional evaluation results and emotion response indications through EEG signals. The validation and findings have laid a foundation for further investigation of relations between people’s general cognitive and emotional responses in evaluating built environment quality and characters.

In the Newtonian limit of general relativity a force acting on a test mass in a central gravitational field is conventionally defined by the attractive Newtonian gravity (inverse square) term plus a small repulsive cosmological force, which is proportional to the slow acceleration of the universe expansion. In this paper we considered the cosmological-force correction due to fast quantum oscillations of the universe scale factor as a potential solution of the cosmological constant problem. These fast fluctuations of the cosmological scale factor violate Lorentz invariance at the Planck scale, and they induce strong changes to the current sign and magnitude of the average cosmological force, thus making it one of the potential probable causes for the modification of Newtonian dynamics in galaxy-scale systems. The modified cosmological force may be responsible for the recently discovered “cosmic-clock” behavior of disk galaxies in the low-redshift universe. The obtained results have strong implications for astroparticle physics since they demonstrate that typical galaxy rotation curves may be obtained without (or almost without) dark-matter particles.

Due to the limitations of satellite antenna technology, current operational microwave soil moisture (SM) data products are typically at tens of kilometers spatial resolutions. Many approaches have thus been proposed to generate finer resolution SM data using ancillary information, but it is still unknown if assimilation of the finer spatial resolution SM data has beneficial impacts on model skills. In this paper, a synthetic experiment is thus conducted to identify the benefits of SM observations at a finer spatial resolution on the Noah-MP land surface model. Results of this study show that the performance of the Noah-MP model is significantly improved with the benefits of assimilating 1 km SM observations in comparison with the assimilation of SM data at coarser resolutions. Downscaling satellite microwave SM observations from coarse spatial resolution to 1 km resolution is recommended, and the assimilation of 1 km remotely sensed SM retrievals is suggested for NOAA National Weather Service and National Water Center.

This paper presents several novel designs of small form factor underwater radio antennas operating in the 2 MHz, 50 MHz and 2.4 GHz bands. These antennas efficiently excite surface electromagnetic waves (SEW) which propagate along the surface of seawater. The antenna operation is made possible due to implementation of an impedance matching enclosure, which is filled with de-ionized water. Enhanced coupling to surface electromagnetic waves is enabled by the enhancement of the electromagnetic field at the antenna apex. These features allow us to make antenna dimensions considerably smaller compared to typical free space designs. They also considerably improve coupling of electromagnetic energy to the surrounding seawater. Since SEW propagation length is considerably larger than the skin depth in seawater, this technique is useful for underwater broadband wireless communication. We conclude that the developed broadband underwater radio communication technique will be useful in networking of unmanned underwater vehicles.

One of the limitations in using spaceborne, microwave radiometer data for atmospheric remote sensing is the nonuniform spatial resolution. Remapping algorithms can be applied to the data to ameliorate this limitation. In this paper, two remapping algorithms, the Backus–Gilbert inversion (BGI) technique and the filter algorithm (AFA), widely used in the operational data preprocessing of the Advanced Technology Microwave Sounder (ATMS), are investigated. The algorithms are compared using simulations and actual ATMS data. Results show that both algorithms can effectively enhance or degrade the resolution of the data. The BGI has a higher remapping accuracy than the AFA. It outperforms the AFA by producing less bias around coastlines and hurricane centers where the signal changes sharply. It shows no obvious bias around the scan ends where the AFA has a noticeable positive bias in the resolution-enhanced image. However, the BGI achieves the resolution enhancement at the expense of increasing the noise by 0.5 K. The use of the antenna pattern instead of the point spread function in the algorithm causes the persistent bias found in the AFA-remapped image, leading not only to an inaccurate antenna temperature expression but also to the neglect of the geometric deformation of the along-scan field-of-views.

Public health and built environment design have a long-intertwined history of promoting a healthy quality of life. They emerged with the common goal of preventing infectious disease outbreaks in urban areas and improving occupants’ living conditions. In recent years, however, the two disciplines have become less engaged and with each developing a distinct focus. To respond to this disconnection, a systematic review was conducted to identify the connection and divergence between public health and built environment design and planning. This paper aims to establish a context for understanding the connections, synergies, and divergence between public health and built environment design disciplines. Further, the four main health factors in the built environment are identified and explained: physical, physiological, biological, and psychological factors. Finally, future trends to reconnect public health with build environment design are then outlined.

Astrophotonics is the application of photonic technologies to channel, manipulate, and disperse light from one or more telescopes to achieve scientific objectives in astronomy in an efficient and cost-effective way. Utilizing photonic advantage for astronomical spectroscopy is a promising approach to miniaturizing the next generation of spectrometers for large telescopes. It can be primarily attained by leveraging the two-dimensional nature of photonic structures on a chip or a set of fibers, thus reducing the size of spectroscopic instrumentation to a few centimeters and the weight to a few hundred grams. A wide variety of astrophotonic spectrometers is currently being developed, including arrayed waveguide gratings (AWGs), photonic echelle gratings (PEGs), and Fourier-transform spectrometer (FTS). These astrophotonic devices are flexible, cheaper to mass produce, easier to control, and much less susceptible to vibrations and flexure than conventional astronomical spectrographs. The applications of these spectrographs range from astronomy to biomedical analysis. This paper provides a brief review of this new class of astronomical spectrographs.

As the cost of satellite missions grow, government agencies are working to increase the relevance and usefulness of the Earth science data that they produce. The US National Aeronautics and Space Administration’s (NASA) early adopter program seeks to formalize partnerships with users of data early within the satellite planning process to ensure the greatest value of the mission. Scientists who are designing the satellite observing system, those who are developing mission data products, and the community who will use them need to work together to determine how satellite data can better inform decision making. NASA is working to initiate engagement with data users much earlier in the satellite program life so that the user needs can be prioritized, continue to engage with users throughout the development cycle, and then include analysis on societal impact after nominal mission life. The Early Adopter Program allows for broad and early engagement with decision makers by encouraging individuals and institutions with clear uses of data to engage with the mission. Early adopters facilitate feedback on mission products during pre-launch and accelerate the utilization of these products post-launch. This paper provides background and detail on how NASA is working to engage with early adopters, describes the partnership between early adopters and NASA missions, and connects the program to improved societal impacts of its satellite missions.

Geographically weighted regression (GWR) is a spatial statistical technique that recognizes that traditional ‘global’ regression models may be limited when spatial processes vary with spatial context. GWR captures process spatial heterogeneity by allowing effects to vary over space. To do this, GWR calibrates an ensemble of local linear models at any number of locations using ‘borrowed’ nearby data. This provides a surface of location-specific parameter estimates for each relationship in the model that is allowed to vary spatially, as well as a single bandwidth parameter that provides intuition about the geographic scale of the processes. A recent extension to this framework allows each relationship to vary according to a distinct spatial scale parameter, and is therefore known as multiscale (M)GWR. This paper introduces mgwr, a Python-based implementation of MGWR that explicitly focuses on the multiscale analysis of spatial heterogeneity. It provides novel functionality for inference and exploratory analysis of local spatial processes, new diagnostics unique to multi-scale local models, and drastic improvements to efficiency in estimation routines. We provide two case studies using mgwr, in addition to reviewing core concepts of local models. We present this in a literate programming style, providing an overview of the primary software functionality and demonstrations of suggested usage alongside the discussion of primary concepts and demonstration of the improvements made in mgwr.

This paper reports on the discovery of a novel three-membrane channel unit exhibiting very steep voltage dependence and strong cooperative behavior. It was reconstituted into planar phospholipid membranes formed by the monolayer method and studied under voltage-clamp conditions. The behavior of the novel channel-former, isolated from Escherichia coli, is consistent with a linearly organized three-channel unit displaying steep voltage-gating (a minimum of 14 charges in the voltage sensor) that rivals that of channels in mammalian excitable membranes. The channels also display strong cooperativity in that closure of the first channel permits the second to close and closure of the second channel permits closure of the third. All three have virtually the same conductance and selectivity, and yet the first and third close at positive potentials whereas the second closes at negative potentials. Thus, is it likely that the second channel-former is oriented in the membrane in a direction opposite to that of the other two. This novel structure is named “triplin.” The extraordinary behavior of triplin indicates that it must have important and as yet undefined physiological roles.