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Purpose: Dental health care professionals (DHCP) are routinely exposed to occupational hazards, such as sharps, putting them at risk of exposure to blood borne pathogens in addition to experiencing psychological effects post-injury. The purpose of this study was to investigate the psychological effects of sharps injuries for students, faculty, and staff at the University of Minnesota School of Dentistry (UMN SOD). Methods: A mixed-mode, electronic and paper, research design was used for the 51-item survey. Participants were recruited from the UMN SOD and included students, faculty, and staff. The survey consisted of items from the Perceived Stress Scale (PSS-10) and Modified Patient Health Questionnaire (PHQ-9). Scores were compared between participants who had and those who had not experienced a sharps injury in the past year. Results: A total of 262 surveys were included in the statistical analysis for a 23.5% response rate. Fifty-six participants (21%) self-reported a sharps injury within the past year. Of those respondents, over half (67%) reported experiencing feelings of anxiety and increased stress (50%) while waiting for blood test results. Conclusion: A majority of participants who reported a sharps injury felt anxious and/or stressed during the month following the injury. While participants may have experienced overall increased stress and anxiety, these findings were not statistically significant. Further research is needed to assess the psychological effects of sharp injuries in DHCPs. [ABSTRACT FROM AUTHOR]