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In this paper, we analyzed a dataset of over 2000 crypto-assets to assess their credit risk by computing their probability of death using the daily range. Unlike conventional low-frequency volatility models that only utilize close-to-close prices, the daily range incorporates all the information provided in traditional daily datasets, including the open-high-low-close (OHLC) prices for each asset. We evaluated the accuracy of the probability of death estimated with the daily range against various forecasting models, including credit scoring models, machine learning models, and time-series-based models. Our study considered different definitions of "dead coins" and various forecasting horizons. Our results indicate that credit scoring models and machine learning methods incorporating lagged trading volumes and online searches were the best models for short-term horizons up to 30 days. Conversely, time-series models using the daily range were more appropriate for longer term forecasts, up to one year. Additionally, our analysis revealed that the models using the daily range signaled, far in advance, the weakened credit position of the crypto derivatives trading platform FTX, which filed for Chapter 11 bankruptcy protection in the United States on 11 November 2022. [ABSTRACT FROM AUTHOR]

Accurately capturing wind speed fluctuations and quantifying the uncertainties has important implications for energy planning and management. This paper proposes a novel hybrid machine learning model to solve the problem of probabilistic prediction of wind speed. The model couples the light gradient boosting machine (LGB) model with the Gaussian process regression (GPR) model, where the LGB model can provide high-precision deterministic wind speed prediction results, and the GPR model can provide reliable probabilistic prediction results. The proposed model was applied to predict wind speeds for a real wind farm in the United States. The eight contrasting models are compared in terms of deterministic prediction and probabilistic prediction, respectively. The experimental results show that the LGB-GPR model improves the point forecast accuracy (RMSE) by up to 20.0% and improves the probabilistic forecast reliability (CRPS) by up to 21.5% compared to a single GPR model. This research is of great significance for improving the reliability of wind speed, probabilistic predictions, and the sustainable development of new energy. [ABSTRACT FROM AUTHOR]

Soil temperature (ST) plays a key role in the processes and functions of almost all ecosystems, and is also an essential parameter for various applications such as agricultural production, geothermal development, and their utilization. Although numerous machine learning models have been used in the prediction of ST, and good results have been obtained, most of the current studies have focused on daily or monthly ST predictions, while hourly ST predictions are scarce. This paper presents a novel scheme for forecasting the hourly ST using weather forecast data. The method considers the hourly ST prediction to be the superposition of two parts, namely, the daily average ST prediction and the ST amplitude (the difference between the hourly ST and the daily average ST) prediction. According to the results of correlation analysis, we selected nine meteorological parameters and combined two temporal parameters as the input vectors for predicting the daily average ST. For the task of predicting the ST amplitude, seven meteorological parameters and one temporal parameter were selected as the inputs. Two submodels were constructed using a deep bidirectional long short-term memory network (BiLSTM). For the task of hourly ST prediction at five different soil depths at 30 sites, which are located in 5 common climates in the United States, the results showed the method proposed in this paper performs best at all depths for 30 stations (100% of all) for the root mean square error (RMSE), 27 stations (90% of all) for the mean absolute error (MAE), and 30 stations (100% of all) for the coefficient of determination (R2), respectively. Moreover, the method adopted in this study displays a stronger ST prediction ability than the traditional methods under all climate types involved in the experiment, the hourly ST produced by it can be used as a driving parameter for high-resolution biogeochemical models, land surface models and hydrological models and can provide ideas for an analysis of other time series data. [ABSTRACT FROM AUTHOR]

While the use of crime data has been widely advocated in the literature, its availability is often limited to large urban cities and isolated databases that tend not to allow for spatial comparisons. This paper presents an efficient machine learning framework capable of predicting spatial crime occurrences, without using past crime as a predictor, and at a relatively high resolution: the U.S. Census Block Group level. The proposed framework is based on an in-depth multidisciplinary literature review allowing the selection of 188 best-fit crime predictors from socio-economic, demographic, spatial, and environmental data. Such data are published periodically for the entire United States. The selection of the appropriate predictive model was made through a comparative study of different machine learning families of algorithms, including generalized linear models, deep learning, and ensemble learning. The gradient boosting model was found to yield the most accurate predictions for violent crimes, property crimes, motor vehicle thefts, vandalism, and the total count of crimes. Extensive experiments on real-world datasets of crimes reported in 11 U.S. cities demonstrated that the proposed framework achieves an accuracy of 73% and 77% when predicting property crimes and violent crimes, respectively. [ABSTRACT FROM AUTHOR]

Since May 2022, over 64,000 Monkeypox cases have been confirmed globally up until September 2022. The United States leads the world in cases, with over 25,000 cases nationally. This recent escalation of the Monkeypox outbreak has become a severe and urgent worldwide public health concern. We aimed to develop an efficient forecasting tool that allows health experts to implement effective prevention policies for Monkeypox and shed light on the case development of diseases that share similar characteristics to Monkeypox. This research utilized five machine learning models, namely, ARIMA, LSTM, Prophet, NeuralProphet, and a stacking model, on the Monkeypox datasets from the CDC official website to forecast the next 7-day trend of Monkeypox cases in the United States. The result showed that NeuralProphet achieved the most optimal performance with a RMSE of 49.27 and R 2 of 0.76. Further, the final trained NeuralProphet was employed to forecast seven days of out-of-sample cases. On the basis of cases, our model demonstrated 95% accuracy. [ABSTRACT FROM AUTHOR]

Cancer is the second most common cause of death in the United States, accounting for 602,350 deaths in 2020. Cancer-related death rates have declined by 27% over the past two decades, partially due to the identification of novel anti-cancer drugs. Despite improvements in cancer treatment, newly approved oncology drugs are associated with increased toxicity risk. These toxicities may be mitigated by pharmacokinetic optimization and reductions in off-target interactions. As such, there is a need for early-stage implementation of pharmacokinetic (PK) prediction tools. Several PK prediction platforms exist, including pkCSM, SuperCypsPred, Pred-hERG, Similarity Ensemble Approach (SEA), and SwissADME. These tools can be used in screening hits, allowing for the selection of compounds were reduced toxicity and/or risk of attrition. In this short commentary, we used PK prediction tools in the optimization of mitogen activated extracellular signal-related kinase kinase 1 (MEK1) inhibitors. In doing so, we identified MEK1 inhibitors with retained activity and optimized predictive PK properties, devoid of hERG inhibition. These data support the use of publicly available PK prediction platforms in early-stage drug discovery to design safer drugs. [ABSTRACT FROM AUTHOR]

A task for environmental health research is to produce complete pollution exposure maps despite limited monitoring data. Satellite-derived aerosol optical depth (AOD) is frequently used as a predictor in various models to improve PM2.5 estimation, despite significant gaps in coverage. We analyze PM2.5 and AOD from July 2011 in the contiguous United States. We examine two methods to aid in gap-filling AOD: (1) lattice kriging, a spatial statistical method adapted to handle large amounts data, and (2) random forest, a tree-based machine learning method. First, we evaluate each model's performance in the spatial prediction of AOD, and we additionally consider ensemble methods for combining the predictors. In order to accurately assess the predictive performance of these methods, we construct spatially clustered holdouts to mimic the observed patterns of missing data. Finally, we assess whether gap-filling AOD through one of the proposed ensemble methods can improve prediction of PM2.5 in a random forest model. Our results suggest that ensemble methods of combining lattice kriging and random forest can improve AOD gap-filling. Based on summary metrics of performance, PM2.5 predictions based on random forest models were largely similar regardless of the inclusion of gap-filled AOD, but there was some variability in daily model predictions. [ABSTRACT FROM AUTHOR]

I analyze damage from hurricane strikes on the United States since 1955. Using machine learning methods to select the most important drivers for damage, I show that large errors in a hurricane's predicted landfall location result in higher damage. This relationship holds across a wide range of model specifications and when controlling for ex-ante uncertainty and potential endogeneity. Using a counterfactual exercise I find that the cumulative reduction in damage from forecast improvements since 1970 is about $82 billion, which exceeds the U.S. government's spending on the forecasts and private willingness to pay for them. [ABSTRACT FROM AUTHOR]