Groundwater management in irrigation areas requires a comprehensive understanding of the interactions between agricultural management practices and the underlying groundwater resource. Unsaturated zone modelling can be used to predict rates of water and solute movement through the soil profile. By incorporating expert knowledge and measured data, it is possible to investigate the relative influence of management vs environmental factors on water and solute movement. The Agricultural Production Systems sIMulator (APSIM) has been applied to simulate the impacts of both environmental factors and agricultural management factors on deep drainage and nitrate leaching in the Lower Burdekin, North Queensland, Australia. Based on the results of this modelling, predicted annual average deep drainage rates were found to be controlled primarily by soil properties, irrigation scheduling, and, to a lesser extent, annual rainfall. The key factors which were found to control nitrate leaching were: irrigation water quality, fertilizer application rates, soil type, crop management, and irrigation scheduling. However, increases in the concentrations of nitrate in irrigation water resulted in a 64-fold increase in predicted nitrate-leaching rates, compared with a 22-fold increase in predicted nitrate-leaching rates associated with increased fertilizer application rates. As significant quantities of nitrate are predicted to be leached below the root zone, the immediate priority should be to increase monitoring of groundwater quality with a focus on quantifying the transport of nutrients to sensitive receptors. [ABSTRACT FROM AUTHOR]