3 results
Search Results
2. Nutritional intervention and neurodevelopmental outcome in infants with suspected cerebral palsy: the Dolphin infant double-blind randomized controlled trial.
- Author
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Andrew, Morag J., Montague‐Johnson, Christine, Laler, Karen, Baker, Bonny, Sullivan, Peter B., Parr, Jeremy R., Qi, Cathy, and Montague-Johnson, Christine
- Subjects
NEURODEVELOPMENTAL treatment for infants ,CEREBRAL palsy ,DOCOSAHEXAENOIC acid ,NUTRITION ,RANDOMIZED controlled trials ,CEREBRAL palsy treatment ,NUCLEOTIDES ,CHOLINE ,CHILD development ,COMPARATIVE studies ,DIET therapy ,RESEARCH methodology ,MEDICAL cooperation ,RESEARCH ,STATISTICAL sampling ,EVALUATION research ,BLIND experiment ,DISEASE complications ,PSYCHOLOGY ,THERAPEUTICS - Abstract
Copyright of Developmental Medicine & Child Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2018
- Full Text
- View/download PDF
3. Effectiveness of acupuncture for vascular cognitive impairment no dementia: a randomized controlled trial.
- Author
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Yang, Jing-Wen, Shi, Guang-Xia, Zhang, Shuai, Tu, Jian-Feng, Wang, Li-Qiong, Yan, Chao-Qun, Lin, Lu-Lu, Liu, Bao-Zhen, Wang, Jun, Sun, San-Feng, Yang, Bo-Feng, Wu, Li-Yu, Tan, Cheng, Chen, Sheng, Zhang, Zhang-Jin, Fisher, Marc, and Liu, Cun-Zhi
- Subjects
NUCLEOTIDES ,COGNITION disorders treatment ,ACUPUNCTURE ,ANALYSIS of covariance ,CEREBROVASCULAR disease ,CHI-squared test ,CONFIDENCE intervals ,FISHER exact test ,MEDICAL cooperation ,PSYCHOLOGICAL tests ,PSYCHOMETRICS ,QUESTIONNAIRES ,RESEARCH ,RESEARCH funding ,STROKE ,T-test (Statistics) ,ACTIVITIES of daily living ,VASCULAR dementia ,RANDOMIZED controlled trials ,TREATMENT effectiveness ,INTER-observer reliability ,EXECUTIVE function ,DATA analysis software ,DESCRIPTIVE statistics ,MANN Whitney U Test ,DISEASE complications ,THERAPEUTICS - Abstract
Objective: To evaluate the effectiveness of acupuncture in patients with vascular cognitive impairment no dementia (VCIND) in comparison with citicoline, an agent for cognitive disturbances associated with chronic cerebral disorders. Design: A randomized controlled multicenter trial. Setting: In three hospitals in Beijing, China. Subjects: A total of 216 patients with VCIND were recruited. Interventions: Patients with VCIND (mean age of 65.4 years) were randomized to receive acupuncture (two sessions per week) or oral citicoline (100 mg three times daily) over three months. Main measures: The primary outcome was the change from baseline to three months in cognitive symptom, measured by Alzheimer's disease Assessment Scale, cognitive subscale (ADAS-cog). Secondary outcomes included changes from baseline to six months in ADAS-cog, executive function measured by the Clock Drawing Test (CDT), and functional disability measured by the Ability of Daily Living (ADL) scale at three and six months. Results: At three months, the acupuncture group had a greater decrease in mean ADAS-cog score (−2.33 ± 0.31) than the citicoline group (−1.38 ± 0.34) with a mean difference of −0.95 (95% CI, −1.84 to −0.07, P = 0.035). The mean change from baseline to six months in ADAS-cog also significantly favored acupuncture treatments (acupuncture change −2.61 vs citicoline −1.25, difference: −1.36 points; 95% CI, −2.20 to −0.51; P = 0.002). There was no difference between the two groups on CDT and ADL scores at either time point. Conclusion: Compared with citicoline, acupuncture has comparable and even superior efficacy with improved cognitive and daily living performance as a complementary and alternative medicine treatment for VCIND. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
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