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This article will analyse factors which, since the end of last century, have made interregional relations very important to understand the world geopolitical and economic order. Interregional relations are defined as those which pertain to relations between regions or between a given state and a given region, or within a megaregion. This evolution results from: the growing demand in the emerging economies and the interaction among them, a new framework of interregional economic relations, and the development of new commercial channels. Finally, this paper will introduce the different articled included in this issue. [ABSTRACT FROM AUTHOR]