1. Numerical study of singularly perturbed differential–difference equation arising in the modeling of neuronal variability
- Author
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Rai, Pratima and Sharma, Kapil K.
- Subjects
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COMPUTATIONAL neuroscience , *PERTURBATION theory , *DIFFERENCE equations , *MATHEMATICAL variables , *BOUNDARY value problems , *NUMERICAL analysis , *APPROXIMATION theory - Abstract
Abstract: The objective of this paper is to present a numerical study of a class of boundary value problems of singularly perturbed differential difference equations (SPDDE) which arise in computational neuroscience in particular in the modeling of neuronal variability. The mathematical modeling of the determination of the expected time for the generation of action potential in the nerve cells by random synaptic inputs in dendrites includes a general boundary-value problem for singularly perturbed differential difference equation with shifts. The problem considered in this paper exhibit turning point behavior which add to the complexity in the construction of numerical approximation to the solution of the problem as well as in obtaining theoretical estimates on the solution. Exponentially fitted finite difference scheme based on Il’in-Allen-Southwell fitting is used on a specially designed mesh. Some numerical examples are given to validate convergence and computational efficiency of the proposed numerical scheme. Effect of the shifts on the layer structure is illuminated for the considered examples. [Copyright &y& Elsevier]
- Published
- 2012
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