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The paper deals with the issues of response to abnormal and emergency situations, including threats of and acts of unlawful interference on vehicles and transport infrastructure facilities of the railways of the Russian Federation. The response process is considered in terms of the regulations of interaction between the units in charge of the response and transfer of information about an accident. Based on the results of the analysis of regulatory documents, the data on the response processes in the event of threats, acts of unlawful interference and other abnormal and emergency situations were structured. An algorithmic model of the response process of the structural units of the railway, forces and units responsible for transport safety on the transport infrastructure facilities and vehicles and other safety authorities under threats, acts of unlawful interference and other abnormal and emergency situations have been developed. [ABSTRACT FROM AUTHOR]