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Understanding the data and reaching accurate conclusions are of paramount importance in the present era of big data. Machine learning and probability theory methods have been widely used for this purpose in various fields. One critically important yet less explored aspect is capturing and analyzing uncertainties in the data and model. Proper quantification of uncertainty helps to provide valuable information to obtain accurate diagnosis. This paper reviewed related studies conducted in the last 30 years (from 1991 to 2020) in handling uncertainties in medical data using probability theory and machine learning techniques. Medical data is more prone to uncertainty due to the presence of noise in the data. So, it is very important to have clean medical data without any noise to get accurate diagnosis. The sources of noise in the medical data need to be known to address this issue. Based on the medical data obtained by the physician, diagnosis of disease, and treatment plan are prescribed. Hence, the uncertainty is growing in healthcare and there is limited knowledge to address these problems. Our findings indicate that there are few challenges to be addressed in handling the uncertainty in medical raw data and new models. In this work, we have summarized various methods employed to overcome this problem. Nowadays, various novel deep learning techniques have been proposed to deal with such uncertainties and improve the performance in decision making. [ABSTRACT FROM AUTHOR]

Payment cards offer a simple and convenient method for making purchases. Owing to the increase in the usage of payment cards, especially in online purchases, fraud cases are on the rise. The rise creates financial risk and uncertainty, as in the commercial sector, it incurs billions of losses each year. However, real transaction records that can facilitate the development of effective predictive models for fraud detection are difficult to obtain, mainly because of issues related to confidentially of customer information. In this paper, we apply a total of 13 statistical and machine learning models for payment card fraud detection using both publicly available and real transaction records. The results from both original features and aggregated features are analyzed and compared. A statistical hypothesis test is conducted to evaluate whether the aggregated features identified by a genetic algorithm can offer a better discriminative power, as compared with the original features, in fraud detection. The outcomes positively ascertain the effectiveness of using aggregated features for undertaking real-world payment card fraud detection problems. [ABSTRACT FROM AUTHOR]

In recent decades, breast cancer has become one of the leading causes of mortality among women. This disease is not preventable because of its unknown causes; however, its early diagnosis increases patients' recovery chances. Machine learning (ML) can be utilized to improve treatment outcomes in healthcare operations while diminishing costs and time. In this research, we suggest two novel feature selection (FS) methods based upon an imperialist competitive algorithm (ICA) and a bat algorithm (BA) and their combination with ML algorithms. This study aims to enhance diagnostic models' efficiency and present a comprehensive analysis to help clinical physicians make more precise and reliable decisions. K-nearest neighbors (KNN), support vector machine (SVM), decision tree (DT), Naive Bayes, AdaBoost (AB), linear discriminant analysis (LDA), random forest (RF), logistic regression (LR), and artificial neural network (ANN) are some of the methods employed. Sensitivity, accuracy, precision, mean absolute error F-score, root mean square error, Kappa, and relative absolute error calculated the performance of the methods. This paper applied a distinctive integration of evaluation measures and ML algorithms using the wrapper feature selection based on ICA (WFSIC) and BA (WFSB) separately. We compared two proposed approaches for the performance of the classifiers. Also, we compared our best diagnostic model with previous works reported in the literature survey. Experimentations were performed on the Wisconsin diagnostic breast cancer (WDBC) dataset. Results reveal that the proposed framework that uses the BA with an accuracy of 99.12% surpasses the framework using the ICA and most previous works. Additionally, the RF classifier in the approach of FS based on BA emerges as the best model and outperforms others regarding its criteria. Besides, the results illustrate the role of our techniques in reducing the dataset dimensions up to 90% and increasing the performance of diagnostic models by over 99%. Moreover, the result demonstrates that there are more critical features than the optimum dataset obtained by proposed FS approaches that have been selected by most ML models, including the standard error of area, concavity, smoothness, perimeter, the worst of texture, compactness, radius, symmetry, smoothness, concavity, and the mean of concave points, fractal dimension, compactness, concavity that can remarkably affect the efficiency of breast cancer prediction. This study illustrates the role of our approaches in enhancing treatment outcomes in healthcare operations. [ABSTRACT FROM AUTHOR]

Gastric Cancer is the most common malignancy of the digestive tract, which is the third leading cause of cancer-related mortality worldwide. The early prognosis methods, especially Machine Learning (ML)-based approaches are one of the main strategies against GC, which have become a necessity to identify and prognosticate the factors that affect the GC. They enable the specialists to accelerate the subsequent clinical management of patients, who suffer from the GC. This paper aims at creating an Ensemble Method inspired from ML to predict the most significant factors of the GC occurrence. The main objective of this research is to predict the probabilities of the GC occurrence and its associated deaths. To achieve this goal, the created EM benefits from some ML-based methods, including Least Absolute Shrinkage and Selection Operator (LASSO)/Ridge Regression, Elastic Net, Logistic Regression (LR), Random Forest (RF), Gradient Boosting Decision Trees (GBDTs), and Deep Neural Network (DNN). The purpose of the provided EM is to lessen the prediction errors for the large number of the patients' features. The main novelties of this research include: (i) A sequential EM created by a Stacking method to predict the probability of the GC and associated deaths; (ii) Benefiting from the significance level to make an accurate prediction; (iii) Employing two Chi-square tests to select the influent features; (iv) Tuning the parameters of the applied ML models to avoid over-fitting and intensifying the errors; (v) Applying different kinds of the regression methods to treat hyper-dimension cases; (vi) A new model for weighting the applied ML models. The outcomes of the implementation of the created EM in seven pioneer hospitals in the field of GC show that the designed EM generates more precise predictions with an accuracy of 97.9% and 76.3% to predict the GC and its associated deaths, respectively. Moreover, the obtained results from the Area Under Curve (AUC) validates and confirms the capability of the created EM to predict the probability of the GC and its related deaths with an accuracy of 98% and 90% to predict the GC and its associated deaths, respectively. [ABSTRACT FROM AUTHOR]